Author(s): Jadhav Sandhya, S. S. Siddheshwar

Email(s): sandhyajadhav421@gmail.com

DOI: 10.52711/2231-5659.2024.00024   

Address: Jadhav Sandhya, S. S. Siddheshwar
Pravara Rural College of Pharmacy, Pravaranagar A/P Loni – 413736, Tal - Rahata, Dist. – Ahmednagar.
*Corresponding Author

Published In:   Volume - 14,      Issue - 2,     Year - 2024


ABSTRACT:
The transdermal drug delivery route is gaining recognition as a promising method, given its advantages such as bypassing hepatic first-pass metabolism, reducing side effects and gastrointestinal issues, and enhancing patient compliance through pain-free self-administration. However, a significant challenge in this route lies in the difficulty of drug penetration through the skin, primarily due to the stratum corneum forming a protective barrier against the external environment. The efficacy of transdermally delivered drugs relies on their ability to cross this barrier and reach the systemic circulation. Penetration enhancers play a crucial role in facilitating this process by increasing skin permeability, thereby maintaining optimal drug levels in the bloodstream. These enhancers can be categorized as chemical, natural, or physical. This review focuses on exploring the potential of natural permeation enhancers for facilitating the transdermal permeation of drugs.


Cite this article:
Jadhav Sandhya, S. S. Siddheshwar. A Review on Natural Penetration Enhancer for Transdermal Drug Delivery System. Asian Journal of Research in Pharmaceutical Sciences. 2024; 14(2):155-8. doi: 10.52711/2231-5659.2024.00024

Cite(Electronic):
Jadhav Sandhya, S. S. Siddheshwar. A Review on Natural Penetration Enhancer for Transdermal Drug Delivery System. Asian Journal of Research in Pharmaceutical Sciences. 2024; 14(2):155-8. doi: 10.52711/2231-5659.2024.00024   Available on: https://ajpsonline.com/AbstractView.aspx?PID=2024-14-2-8


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