A. A. Shinde, A. B. Velhal, P. D. Jadhav, V. K. Redasani
A. A. Shinde*, A. B. Velhal, P. D. Jadhav, V. K. Redasani
Yashoda Shikshan Prasarak Mandal’s, Yashoda Technical Campus, Faculty of Pharmacy, Wadhe NH4, Satara. 415011.
Volume - 12,
Issue - 4,
Year - 2022
Emulgel is a developing topical drug delivery technique that, if more attempt is put for the preparations with majority of topically effective drugs, will be a benefit for dermal care and cosmetic products due to its dual release control system (gel and emulsion). The direct availability of the skin as a target organ for diagnosis and treatment is a distinguishing characteristic of dermatological pharmacology. Transparent gels have grown in popularity as a crucialclass of semisolid preparations in both cosmetics and pharmaceuticals. Despite the many benefits of gels, one major limitation is the delivery of water insoluble drugs because solubility acts as a barricade and a problem arises during drug release. As a result, an emulsion-based strategy is being employed to bypass this barrier, allowing even a hydrophobic medicinal component to benefit from the special features of gels. Emulgels are dosage forms made up of gels and emulsions that have been mixed. The major goal is to generate a jellified emulsion that will reduce systemic side effects and produce a more prominent effect with fewer drug doses. Thixotropic, greaseless, good Spreadability, easily removable, soothing, soluble in water, long shelf life, bio-friendly, translucent & appealing look are only a few of the benefits of emulgels for dermatological use. As a result, emulgels can be utilize as a good topical drug delivery mechanism than the currently existing traditional systems.
Cite this article:
A. A. Shinde, A. B. Velhal, P. D. Jadhav, V. K. Redasani. A Review on Emulgel: Improvement of Topical Absorption of Drug. Asian Journal of Research in Pharmaceutical Sciences. 2022; 12(4):335-0. doi: 10.52711/2231-5659.2022.00057
A. A. Shinde, A. B. Velhal, P. D. Jadhav, V. K. Redasani. A Review on Emulgel: Improvement of Topical Absorption of Drug. Asian Journal of Research in Pharmaceutical Sciences. 2022; 12(4):335-0. doi: 10.52711/2231-5659.2022.00057 Available on: https://ajpsonline.com/AbstractView.aspx?PID=2022-12-4-13
1. AVS Madhu L, JN Suresh K, Sojana N, Mounika N, Priyanka G, Venkatesh A. Design and Optimization of Clotrimazole Emulgel by Using Various Polymers. Asian J. Pharm. Tech. 2021;11(1):41-47.
2. Sawant A. A, Mohite S.K. Formulation and Evaluation of Itraconazole Emulgel for Topical Drug Delivery. Asian Journal of Pharmacy and Technology. 2015;5(2):91-96.
3. Pravallika A, Priyanka R, Formulation and Evaluation of Aceclofenac Topical Emulgel. International Journal of Advanced Technology and Innovative Research. 2019;11(2):43-48.
4. Shaikh S. S, Parveen P, Shri Rekha M, Deepthi K, Sowjanya Ch, Seetha Devi A, Emulgel- A Novel Surrogate Approach for Transdermal Drug Delivery System. Indo American Journal of Pharmaceutical Research. 2014;4(11):1462-1472.
5. Redkar M. R, Hasabe P. S, Jadhav S. T, Mane P.S, Kare D. J. Review on Optimization Base Emulgel Formulation. Asian J. Pharm. Tech.2019;9(3):228-237.
6. Kalia Y. N, Guy R. H, Modeling Transdermal Drug Release. Adv Drug Deli Rev. 2001,48:159-72.
7. Ayub C.A, Gomes ADM, Lima MVC, Vianna-Soares CD, Ferreira LMA, Topical Delivery of Fluconazole: In Vitro Penetration and Permeation Using Emulsion as Dosage Forms, Drug. Dev. Ind. Pharm, 2007;33:273-280.
8. Kute S. B, Saudagar R.B, Emulsified Gel A Novel Approach for Delivery of Hydrophibic Drugs: An Overview. J. Adv. Pharm. Edu. & Research. 2013;3(4):368-379.
9. Phad A. R, Nandgude T. D, Ganapathy S. R, Emulgel: A Comprehensive Review for Topical Delivery of Hydrophobic Drugs. Asian Journal of Pharmaceutics. 2018;12(2):382-393.
10. Hasan S, Bhandari S, Sharma A, Garg P. Emulgel: A Review. Asian Journal of Pharmaceutical Research. 2021;11(4):263-8.
11. Pant S, Badola A, Pant W. A Review on Emulgel Novel Approach for Topical Drug Delivery System. World J. Pharm Sci. 2015;4:1728-43.
12. Ingle S, Tegeli V, Chandakavate B, Matole V, Kirdak O, Gophane G, Tonapr S, Birajdar A, Nangare S, Adlinge S, Ramansehetti S, Yadav k, Patil A, Khare A, Ubale S, Dulange V, Habib B, Mittha J. A Brief Review on Emulgel: A Novel Topical Drug Delivery System. Res. J. Pharma. Dosage Forms and Tech. 2021;13(1):25-30.
13. Krishna Veni N, Yashwanti P, Hemalata B, Padmalata K. A Review on Emulgels as a Novel Approach for Topical Drug Delivery. Asian Journal of Research in Pharmaceutical Science. 2022;12(2):163-8.
14. Samala M. L, Gowripattapu S, Role of Polymer as Gelling Agents in the Formulation of Emulgel. iMedPub Journals. 2016;2(1):1-8.
15. Das A, Ahemad A. B, Natural Permeation Enhancer for Topical Drug Delivery System and Permeation Evaluation: A Review. Asian Journal of Pharmaceutical and Clinical Research. 2017;10(9):5-9.
16. Khullar R, Kumar D, Seth Nimrata, Saini S, Formulation and Evaluation of Mefenamic Acid Emulgel for Topical Delivery. Saudi Pharmaceutical Journal. 2012; 20:63-67.
17. Eshwarnath S, Swetha K, Preethi P. J, Priyanka B, Reddy K. K. Emulgel: Review on Novel Approach to Topical Drug Delivery. Asian J. Pharm. Res.2014;4(1):4-11.
18. Ambhore N. P, Dandagi P. M, Gadad A. P, Mansora P, Formulation and Characterization of Tapentadol Loaded Emulgel for Topical Application. Indian Journal of Pharmaceutical Education and Research. 2017;51(4):525-535.
19. Vijaya Bhanu P, Shanmugam V, Lakshmi P. K, Development and Optimization of Novel Diclofenac Emulgel for Topical Drug Delivery. International Journal of Comprehensive Pharmacy. 2011;9(10):1-4.
20. Sheikh A. A, Siddiqui S. A, Siddiqui A. R, Zahid Z, Aejaz A, Formulation Development and Characterization of Aceclofenac Gel Containing Linseed Oil and Ginger Oleoresin. International Journal of Pharm Tech Research. 2011;3(3):1448-1453.
21. Yadav S, Mishra M, Tiwari A, Shukla A, Emulgel: A New Approach for Enhanced Topical Drug Delivery. International Journal of Current Pharmaceutical Research. 2017;9(1):15-19.
22. Mwangi A. N, Njogu P. M, Maru S. M, Njugna M, Njaria P. M, Kirirri G. K, Mathenge A.W, Meloxicam Emulgel for Topical Management of Rheumatism: Formulation Development, in vitro and in vivo Characterization. Saudi Pharmaceutical Journal. 2021; 29:351-360.
23. Bhosale M. S, Khade S, Patil A. S, Raut I. D, Manojkumar M, Jadhav K. K, Emulgel: A Novel Approach to Topical Drug Delivery. Levant Journal. 2021;20(7):394-406.
24. Amminbavi D, Lakshmi Prasanna N. Assessment of In Vitro Wound Healing Potential of Hibiscus Leaf Extract Emulgel. Asian J. Pharm.Res. 2020;10(2):67-72.
25. Gupta G.D, Gaud R.S. Release Rate of Nimesulide from Different Gellants. Indian J Pharm Sci. 1999; 61:229-234.
26. Shah R S. Formulation and Evaluation of Turmeric Emulgel. Asian Journal of Pharmacy and Technology. 2021;11(3):213-9.
27. Singh V, Singh S, formulation and Evaluation of Aceclofenac Topical Emulgels. InternationalJournal of Modern Pharmaceutical Research. 2021;5(4):151-157.
28. MakadiaH. A, Bhatt A. Y, Parmar R. B, Paun J. S, Tank H. M. Self-Nano Emulsifying Drug Delivery System (SNEDDS): Future Aspects. Asian Journal of Pharmaceutical Research. 2013;3(1):20-26.
29. Chaudhari P, Ajab A, Malpure P, Kolsure P, Sanap D, Development and in vitro evaluation of thermoreversible nasal gel Formulation of Rizatripan Benzoate. Indian J Pharm Educ Res. 2009; 43:55-62.
30. Shreevidya V.S, An overview on Emulgel, International Journal of Pharmaceutical and Phytopharmaceutical Research. 2019;9(1);92-97.