Author(s):
Khairnar Jagruti Girdhar, Javesh K. Patil
Email(s):
vikram.gharge@zuventus.com
DOI:
10.52711/2231-5659.2026.00040
Address:
Khairnar Jagruti Girdhar1, Javesh K. Patil2
1Department of Pharmaceutical Quality Assurance, P.S.G.V.P. Mandal's College of Pharmacy, Shahada, 425409, Maharashtra, India.
2Assistant Professor, Department of Pharmaceutical Quality Assurance, P.S.G.V.P Mandal’s College of Pharmacy, Shahada, 425409 Maharashtra, Nandurbar.
*Corresponding Author
Published In:
Volume - 16,
Issue - 3,
Year - 2026
ABSTRACT:
The purpose was to create for topical administration of tazarotene capable of enabling regulated and localized release of the encapsulated medication in order to avoid undesirable effects associated with its topical use. The retinoid are types of chemical substances that are connected chemically to vitamin The main reason retinoids are employed in is because they control the proliferation of epithelial cells.The skin to its active form, tazarotene acid, which influences cell proliferation and differentiation by regulating Chemistry gene expression in acne and psoriasis.Tazarotene is important for its effectiveness in treating inflammatory and non-inflammatory skin diseases, such as plaque psoriasis, acne, and symptoms of sun-damaged skin. It can reduce thick scales, acne lesions, and indicators of aging including tiny wrinkles and discolouration by slowing down the rapid proliferation of skin cells, lowering inflammation, and encouraging better skin cell turnover.
Cite this article:
Khairnar Jagruti Girdhar, Javesh K. Patil. A Compressive Review on: Tazarotene. Asian Journal of Research in Pharmaceutical Sciences. 2026; 16(3):271-7. doi: 10.52711/2231-5659.2026.00040
Cite(Electronic):
Khairnar Jagruti Girdhar, Javesh K. Patil. A Compressive Review on: Tazarotene. Asian Journal of Research in Pharmaceutical Sciences. 2026; 16(3):271-7. doi: 10.52711/2231-5659.2026.00040 Available on: https://ajpsonline.com/AbstractView.aspx?PID=2026-16-3-9
REFERANCE:
1. Sami N. Topical retinoids In: Wolverton SE, ed. Comprehensive dermatologic drug therapy (3rd ed). Netherlands: Elsevier; 2103. p. :505-17.
2. Ghadially R, Halkier-Sorensen L, Elias PM: Effectsof petrolatum on stratum corneum structure and func-tion. J. Am. Acad. Dermatol. 1992; 26: 387-396.
3. Liem WH, Mccullough JL, Weinstein GD: Effective-ness of topical therapy for psoriasis: results of a na-tional survey. Cutis. 1995; 55: 306-310
4. Liem WH, Mccullough JL, Weinstein GD: Effective-ness of topical therapy for psoriasis: results of a na-tional survey. Cutis. 1995; 55:306-310.
5. El-Domyati M, Attia S, Saleh F, et al. Intrinsic aging vs. photoaging: a comparative histopathological, immunohistochemical, and ultrastructural study of skin. Experimental Dermatology. 2002; 11: 398–405. doi: 10.1034/j.1600-0625.2002.110502. x.
6. Hadshiew IM, Eller MS, Gilchrest BA. Skin Aging and Photoaging: The Role of DNA Damage and Repair. American Journal of Contact Dermatitis. 2000; 11: 19–25. doi: 10.1016/s1046-199x(00)90028-9.
7. International Conference on Harmonization. Validation of Analytical Procedure, Text and Methodology Q2 (R1), IFPMA, Geneva, Switzerland. 2005
8. J. Krzek, H Woltyńska, U Hubicka. Determination of gentamicin sulphate in injection solutions by derivative spectrophotometry. Analytical Letters. 2009; 42: 473-482.
9. Sahasranaman S, Tang Y, Biniasz D, Hochhaus GA. A sensitive LCMS method for the quantification of mometasone furoate in human plasma. J Chromatogr B. 2005; 819: 175–179.doi: 10.1016/j.jchromb.2005.01.018. http://dx.doi.org/10.1016/j.jchromb.2005.01.018. [
10. Chen G, Pramanik BN, Liu YH, Mirza UA. Applications of LC/MS in structure identifications of small molecules and proteins in drug discovery. J Mass Spectrom. 2007; 42: 279–287. doi: 10.1002/jms.1184.
11. Bozzuto G, Lingan A. Liposomes as nanomedical devices. International Journal of Nanomedicine. 2015; 10: 975.
12. 12.Nagaraju Rajana, D.V Ramana, J. Moses Babu, K. Basavaiah, Dharamasoth Rama Devi First published: 10 July 2020 https://doi.org/10.1002/sscp.202000009
13. Hematology: An experience ina teaching hospital. Kathmandu University Medical Journal 2014; 12(4): 306-307.
14. Zayed MA, Abdel-Basset MH. Spectrophotometric micro determination of tretinoin isotretinoin using iodine and tazarotene micro determination via reaction with Rose-Bengal reagent. Egyptian Journal of Chemistry. 2018; 61(1): 143–153.
15. Chopade VV, Tembhurkar NB, Jadhav SB, Chaudhari PD. Development and validation of a stability indicating assay method of Mefloquine HCI by using different stress degradation conditions. Journal of Pharmacy Research. 2012; 5:2631-2635.
16. X. Cao et al. Characterization of impurities in semi-synthetic vinorelbine bitartrate by HPLC-MS with mass spectrometric shift technique J. Pharm. Biomed. Anal. 2005.