Author(s): Sali S R, Gondkar S B, Saudagar R B

Email(s): shubhamsali44@gmail.com

DOI: 10.5958/2231-5659.2018.00011.5   

Address: Sali S R1 , Gondkar S B2 , Saudagar R B3
1Department of Pharmaceutics, R. G. Sapkal College of Pharmacy, Anjaneri, Nashik-422213, Maharashtra, India
2Department of Pharmaceutics, R.G Sapkal College of Pharmacy, Anjaneri, Nashik-422213, Maharashtra, India
3Department of Pharmaceutical Chemistry, R. G. Sapkal College of Pharmacy, Anjaneri, Nashik-422213, Maharashtra, India
*Corresponding Author

Published In:   Volume - 8,      Issue - 1,     Year - 2018


ABSTRACT:
The widely effective and most common form of drug delivery is parenteral administration for active drug substances with poor bio-availability and the drugs with a narrow therapeutic index. Though parenteral administration of drug is often critical and associated with problems such as limited number of acceptable excipients, stringent requirements of aseptic production process, safety issues, patient noncompliance. Still this route maintains its value due to special advantages like quicker onset of action in case of emergency, target the drug quickly to desired site of action, prevention of first pass metabolism etc. The application of advanced drug delivery technology to parenteral administration lead to development of liposomes, nanosuspensions, solid implants etc. to overcome limitations of conventional parenteral delivery. Solid implants are reported to produce very reproducible release profiles. However, because of their size, they require surgical implantation or the use of large trochars to administer the product. Delivery systems consisting of microparticles can be injected into the body using conventional needles and syringes and have been the most widely accepted biodegradable polymer system for parenteral use. However, the manufacturing processes for microparticles are often complex and difficult to control leading to batch-to-batch product non uniformity. These methods of administration often limit the product's market potential due to patient and physician acceptance issues. Therefore, a delivery system that combines the simplicity and reliability of solid implant devices alongwith convenience and ease of administration of microparticles is desired. In situ gel forming systems represent a desired alternate. This article gives the idea about In situ gel forming system to provide drug release in sustained release manner.


Cite this article:
Sali S R , Gondkar S B , Saudagar R B. A Review on: Atrigel – The Magical Tool. Asian J. Res. Pharm. Sci. 2018; 8(1):48-54. doi: 10.5958/2231-5659.2018.00011.5


Recomonded Articles:

Author(s): Lakshmi Prasanna J., Deepthi B., Rama Rao N.

DOI:         Access: Open Access Read More

Author(s): Saudagar R. B., Sarika V. Khandbahale

DOI: 10.5958/2231-5659.2017.00005.4         Access: Open Access Read More

Author(s): Yogita R. Indalkar, Nayana V. Pimpodkar, Puja S. Gaikwad, Anita S. Godase

DOI: 10.5958/2231-5659.2016.00010.2         Access: Open Access Read More

Author(s): AK Mohiuddin

DOI: 10.5958/2231-5659.2019.00004.3         Access: Closed Access Read More

Author(s): Pratibha Gavarkar, Pramod Patil, Akshay Sutar, Shridhar Rasal, Dyaneshwar Surwase

DOI: 10.5958/2231-5659.2016.00029.1         Access: Open Access Read More

Author(s): Sana Banu, Syeda Ayesha Farheen

DOI: 10.5958/2231-5659.2019.00015.8         Access: Closed Access Read More

Author(s): Pramod Patil, Someshwara Rao B, Suresh V Kulkarni, Basavaraj, Chetan Surpur , Anand Ammanage

DOI:         Access: Open Access Read More

Author(s): Roshani Bhalerao, Akshay Patil, Dinesh Rishipathak, Sanjay Kshirsagar

DOI: 10.5958/2231-5659.2017.00029.7         Access: Open Access Read More

Author(s): Rajendra Jangde

DOI:         Access: Open Access Read More

Author(s): Aduema W., Amah A. K, Wariso A.C

DOI: 10.5958/2231-5659.2018.00001.2         Access: Open Access Read More

Author(s): Sourabh S. Baghel, Sonal Dangi, Prashant Soni, Priya Singh, Yogesh Shivhare

DOI:         Access: Open Access Read More

Author(s): D.M. Shinkar, Aarif S. Khatik, R.B. Saudagar

DOI: 10.5958/2231-5659.2016.00022.9         Access: Open Access Read More

Author(s): S. More, T. Ghadge, S. Dhole

DOI:         Access: Open Access Read More

Author(s): Mohammad Yaqub Khan, Irfan Aziz, Imtiyaz Ahmad, Maryada Roy

DOI: 10.5958/2231-5659.2015.00029.6         Access: Open Access Read More

Author(s): Surekha Baghel, Bina Gidwani, Chanchal Deep Kaur

DOI: 10.5958/2231-5659.2017.00009.1         Access: Open Access Read More

Author(s): Amit Roy, Ananta Choudhury, Tapan Kishor Nayak

DOI:         Access: Open Access Read More

Author(s): Tabasum Siraj Mulla, Monika Sanjay Thorat, Yogita Rayate, Manoj Nitalikar

DOI: 10.5958/2231-5659.2019.00021.3         Access: Closed Access Read More

Asian Journal of Research in Pharmaceutical Sciences (AJPSci) is an international, peer-reviewed journal, devoted to pharmaceutical sciences....... Read more >>>

RNI: Not Available                     
DOI: 10.5958/2231-5659 


Recent Articles




Tags