Volume No. :   8

Issue No. :  1

Year :  2018

ISSN Print :  2231-5640

ISSN Online :  2231-5659


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Formulation and Evaluation of Rutin Loaded Nanosponges

Address:   K.Vijaya Sri*, Guda Santhoshini, D. Ravi Sankar, K.Niharika
Malla Reddy College of Pharmacy, (Affiliated to OsmaniaUniversity), Secunderabad, Telangana
*Corresponding Author
DOI No: 10.5958/2231-5659.2018.00005.X

The main objective of this research was to develop rutin nanosponges and evaluate the potential of nanosponges for the delivery oral route. Rutin exhibited as antioxidant, anti-inflammatory, anti-allergic and antiviral activity. But its, poor absorption from the gastrointestinal tract is slow and irregular, probably due to their less solubility and slow dissolution rate. Rutin-loaded nanosponges were prepared by emulsion solvent diffusion method. Nanosponges were evaluated for various physicochemical parameters like FT-IR, DSC, entrapment efficiency ,SEM, particle size, zeta potential and in vitro drug release. FT-IR study reveals the there was no physical and chemical interaction observed between the excipients and drug in combination. Rutin-loaded nanosponges enhanced the drug release when compare to the pure rutin.
Rutin Loaded Nanosponges
K.Vijaya Sri, Guda Santhoshini, D. Ravi Sankar, K.Niharika. Formulation and Evaluation of Rutin Loaded Nanosponges. Asian J. Res. Pharm. Sci. 2018; 8(1):21-24.
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