Recent Trends in Multiple Emulsion- A Comprehensive Review

Sarika S. Lokhande

doi:10.5958/2231-5659.2019.00032.8

Asian Journal of Research in Pharmaceutical Sciences

ISSN

2231-5659 (Online)
2231-5640 (Print)

Submit Article

Recent Trends in Multiple Emulsion- A Comprehensive Review

Author(s): Sarika S. Lokhande

Email(s): sarikalokhande04@gmail.com

DOI: 10.5958/2231-5659.2019.00032.8

Address: Sarika S. Lokhande*
GES College of Pharmacy, Limb, Satara, Maharashtra
*Corresponding Author

Published In: Volume - 9, Issue - 3, Year - 2019

View HTML

View PDF

ABSTRACT:
Multiple emulsions are complex polydispersed systems where both oil in water and water in oil emulsion exists concurrently which are stabilized by lipophillic and hydrophilic surfactants respectively. The ratio of these surfactants is important in achieving stable multiple emulsions. Among water-in-oil-in-water (w/o/w) and oil-in-water-in-oil (o/w/o) type multiple emulsions; the previous has wider areas of application. Formulation, preparation techniques and in vitro characterization methods for multiple emulsions are reviewed. It finds extensive range of applications in controlled or sustained drug delivery, targeted delivery, taste masking, bioavailability improvement, enzyme immobilization, etc. Multiple emulsions have also been employed as transitional step in the microencapsulation process and are the systems of increasing interest for the oral delivery of hydrophilic drugs, which are unbalanced in gastrointestinal tract like proteins and peptides Preparation of monodispersed multiple emulsion is important in DDS to improve their stability and to facilitate control of their properties..The study concluded that stable multiple emulsion with high entrapment efficiency can be prepared by two step emulsification method using Spans40, 60, 80 as primary emulsifier and Tween80 as secondary emulsifier.

Keywords:

Cite this article:
Sarika S. Lokhande. Recent Trends in Multiple Emulsion- A Comprehensive Review. Asian J. Res. Pharm. Sci. 2019; 9(3):201-208. doi: 10.5958/2231-5659.2019.00032.8

Cite(Electronic):
Sarika S. Lokhande. Recent Trends in Multiple Emulsion- A Comprehensive Review. Asian J. Res. Pharm. Sci. 2019; 9(3):201-208. doi: 10.5958/2231-5659.2019.00032.8 Available on: https://ajpsonline.com/AbstractView.aspx?PID=2019-9-3-10

Gelucire: An Optional Innovative Tool for both Sustained and Fast Release of Drugs in Treating Diabetes Mellitus Type II Disease

Author(s): Harikrishnan.V, Sreejith. M, Elthose. M.J, Akash Marathakam

DOI: 10.5958/2231-5659.2017.00006.6 Access: Open Access Read More

Different Techniques for Preparation of Nanosuspension with Reference to its Characterisation and various Applications - A Review

Author(s): Pawar Pravin, Yadav Adhikrao, Gharge Varsha

DOI: 10.5958/2231-5659.2018.00035.8 Access: Open Access Read More

Formulation, Characterization and In Vitro Evaluation of Lamivudine Microspheres

Author(s): Phalguna Yadagiri, Rama Rao Korapati

DOI: Access: Open Access Read More

An Approach to Enhance Solubility of Gatifloxacin by Solid Dispersion Technique

Author(s): Divya B., Sabitha P., Ravindra Reddy, M. Kranthi Kumar Reddy , B.Narasimha Rao

DOI: Access: Open Access Read More

Asian Journal of Research in Pharmaceutical Sciences (AJPSci) is an international, peer-reviewed journal, devoted to pharmaceutical sciences....... Read more >>>

RNI: Not Available
DOI: 10.52711/2231-5659