Author(s): Tripti Jain, Amber Vyas, Darshan Dubey, Kamlesh Dashora, Vishal Jain

Email(s): vishaljain123@gmail.com

DOI: 10.52711/2231-5659.2022.00047   

Address: Tripti Jain1, Amber Vyas2, Darshan Dubey3, Kamlesh Dashora3, Vishal Jain2*
1Chhattisgarh Food and Drug Administration, Mahasamund (CG).
2University Institute of Pharmacy, Pt. Ravishankar Shukla University, Raipur (C.G.).
3Institute of Pharmacy, Vikram University, Ujjain (MP).
*Corresponding Author

Published In:   Volume - 12,      Issue - 4,     Year - 2022


ABSTRACT:
Eladi gutika is official in Ayurvedic formulary of India and used as a remedy for Kasa (Cough), Svasa (Asthma), Bhrama (Vertigo), Raktapitta (Bleeding disorders), Jvara (Fever), Amvata (Rheumatism) etc. The present paper is an effort to develop the routine fingerprinting method for quality control parameter of Eladi gutika by high performance thin layer chromatography using glycyrrhizinic acid as an internal standard. The HPTLC estimation was carried out with three laboratory batches and one marketed formulation Eladi gutika and crude drug containing glycyrrhizinic acid. The concentration of glycyrrhizinic acid present in raw material was found to be 8.2201±0.497w/w in G. glabra and in three identical laboratory batch of Eladi gutika EG-I, EG -II and EG -III, was found to be 1.4945 ± 0.293, 1.4963 ± 0.763%, 1.4944± 0.864w/w respectively. The glycyrrhizinic acid content in all the three different batches is found to be in close proximities with each other. The results were comparable to marketed formulations. Hence the present method is simple, sensitive, precise and accurate and can be adopted for routine fingerprinting method for quality control of Eladi gutika.


Cite this article:
Tripti Jain, Amber Vyas, Darshan Dubey, Kamlesh Dashora, Vishal Jain. Development of Fingerprinting Method for Estimation Glycyrrhizinic acid in Ayurvedic formulation Eladi Gutika: A HPTLC approach. Asian Journal of Research in Pharmaceutical Sciences. 2022; 12(4):277-0. doi: 10.52711/2231-5659.2022.00047

Cite(Electronic):
Tripti Jain, Amber Vyas, Darshan Dubey, Kamlesh Dashora, Vishal Jain. Development of Fingerprinting Method for Estimation Glycyrrhizinic acid in Ayurvedic formulation Eladi Gutika: A HPTLC approach. Asian Journal of Research in Pharmaceutical Sciences. 2022; 12(4):277-0. doi: 10.52711/2231-5659.2022.00047   Available on: https://ajpsonline.com/AbstractView.aspx?PID=2022-12-4-3


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