Author(s):
Pranoti S. Shirke, Namira F. Sayyad, Omkar A. Devade, Laxmikant M. Purane, Vivekkumar K. Redasani
Email(s):
pranoti0250@gmail.com
DOI:
10.52711/2231-5659.2025.00038 
Address:
Pranoti S. Shirke*, Namira F. Sayyad, Omkar A. Devade, Laxmikant M. Purane, Vivekkumar K. Redasani
Department of Pharmacology, YSPM’s Yashoda Technical Campus, Satara, 415011, Maharashtra, India.
*Corresponding Author
Published In:
Volume - 15,
Issue - 3,
Year - 2025
ABSTRACT:
Polycystic ovary syndrome is a highly prevalent endocrine metabolic disorder characterized by polycystic ovaries, chronic anovulation and hyperandrogenism leading to symptoms of menstrual irregularity, infertility and hirsutism. Genetic predisposition, raised insulin level, hormonal imbalance, contraceptive pills, stress are causes of PCOS. Certain synthetic medication like metformin, clomiphene citrate, spironolactone etc. and herbal medication like zingiber officinale, Lepidium meyenil, Foeniculum vulgare etc. have the advantages to reduce PCOS. In this review causes, pathophysiology and treatment including synthetic and herbal medication which plays crucial role in prophylaxis or treatment of PCOS are summarized. It is concluded that herbal medication along with lifestyle management shows steady efficacy and little adverse effect making them a promising option for treating PCOS.
Cite this article:
Pranoti S. Shirke, Namira F. Sayyad, Omkar A. Devade, Laxmikant M. Purane, Vivekkumar K. Redasani. A Review on Polycystic Ovarian Syndrome. Asian Journal of Research in Pharmaceutical Sciences. 2025; 15(3):250-8. doi: 10.52711/2231-5659.2025.00038
Cite(Electronic):
Pranoti S. Shirke, Namira F. Sayyad, Omkar A. Devade, Laxmikant M. Purane, Vivekkumar K. Redasani. A Review on Polycystic Ovarian Syndrome. Asian Journal of Research in Pharmaceutical Sciences. 2025; 15(3):250-8. doi: 10.52711/2231-5659.2025.00038 Available on: https://ajpsonline.com/AbstractView.aspx?PID=2025-15-3-5
REFERENCES:
1. Who.int. [cited 2025 Apr 24]. Available from: https://www.who.int/news-room/fact-sheets/detail/polycystic-ovary-
2. Duvey Brijesh Kumar C, Subash P. Parashar Bharat, Dharmesh Sharma Dhamija Hitesh Effect of Obesity on Fertility in Women with Polycystic Ovary Syndrome Asian J. Dharmesh Sharma Dhamija Hitesh Effect of Obesity on Fertility in Women with Polycystic Ovary Syndrome Asian J Res Pharm Sci. 2011; 1:127–30
3. Polycystic Ovary Syndrome (PCOS) booklet [Internet]. Dr Victoria Nisenblat. 2024 [cited 2025 Apr 24]. Available from: https://gynrc.com.au/assets/polycystic-ovary-syndrome-pcos/
4. Shoukath U, Shoukath U, Sultana S, Uddin MN. Polycystic Ovary Syndrome (PCOS): A Thief of Womenhood. Asian J Res Pharm Sci [Internet]. 2018; 8(2):68. Available from: http://dx.doi.org/10.5958/2231-5659.2018.00014.0
5. Musmar S, Afaneh A, Mo’alla H. Epidemiology of polycystic ovary syndrome: a cross sectional study of university students at An-Najah national university-Palestine. Reprod Biol Endocrinol [Internet]. 2013; 11(1):47. Available from: http://dx.doi.org/10.1186/1477-7827-11-47
6. Kumar R, Gautam GK, Pundir S, Zaidi S, Gupta C. Treatment of human infertility. Asian J Res Pharm Sci [Internet]. 2021; 11(2):160–4. Available from: http://dx.doi.org/10.52711/2231-5659.2021-11-2-12
7. Legro RS, Strauss JF. Molecular progress in infertility: polycystic ovary syndrome. Fertil Steril [Internet]. 2002; 78(3):569–76. Available from: http://dx.doi.org/10.1016/s0015-0282(02)03275-2
8. Kosova G, Urbanek M. Genetics of the polycystic ovary syndrome. Mol Cell Endocrinol [Internet]. 2013; 373(1–2):29–38. Available from: http://dx.doi.org/10.1016/j.mce.2012.10.009
9. Cooney LG, Dokras A. Beyond fertility: polycystic ovary syndrome and long-term health. Fertil Steril [Internet]. 2018; 110(5):794–809. Available from: http://dx.doi.org/10.1016/j.fertnstert.2018.08.021
10. Teede H, Deeks A, Moran L. Polycystic ovary syndrome: a complex condition with psychological, reproductive and metabolic manifestations that impacts on health across the lifespan. BMC Med [Internet]. 2010; 8(1): 41. Available from: http://dx.doi.org/10.1186/1741-7015-8-41
11. Zambare KK, Thalkari AB, Tour NS, Reddy KV. Herbal Remedies for treatment of Polycystic Ovary Syndrome. Asian J Pharm Technol [Internet]. 2019; 9(2): 112. Available from: http://dx.doi.org/10.5958/2231-5713.2019.00019.9
12. Gade A, Sawant R, Parkar S, Kegade P. Polycystic ovary syndrome: An overview, diagnosis and treatment of pcos. Asian J Pharm Technol [Internet]. 2020; 10(4):265–72. Available from: http://dx.doi.org/10.5958/2231-5713.2020.00044.6
13. S. Sarawad S. Polycystic Ovary Syndrome (PCOS): A comprehensive review. Int J Adv Nurs Manag [Internet]. 2023; 264–5. Available from: http://dx.doi.org/10.52711/2454-2652.2023.00059
14. Boomsma CM, Eijkemans MJC, Hughes EG, Visser GHA, Fauser BCJM, Macklon NS. A meta-analysis of pregnancy outcomes in women with polycystic ovary syndrome. Hum Reprod Update [Internet]. 2006; 12(6): 673–83. Available from: http://dx.doi.org/10.1093/humupd/dml036
15. Babu A, Veerasamy R, Sivadasan S. Metformin-A drug of plant origin. Res J Pharm Technol [Internet]. 2018; 11(6): 2701. Available from: http://dx.doi.org/10.5958/0974-360x.2018.00499.7
16. Ray A. Potential properties, used and scope of Azadirachta indica in human health care. Research J Science and Tech. 2012; 4(2): 55–8
17. Revathi R, Julius A. Effect of LH/FSH ratio and its correlation with insulin resistance in PCOS obese woman of reproductive age group. Res J Pharm Technol [Internet]. 2018; 11(6): 2217. Available from: http://dx.doi.org/10.5958/0974-360x.2018.00410.9
18. Suji A, Kumari RJ, Santha NJ. A Quasi Experimental study to assess the Effectiveness of the Video assisted Teaching Programme on Knowledge and Self Reported Practices Related to concepts of Polycystic Ovary Syndrome among Adolescent girls in Selected Schools, Madurai, Tamil Nadu. Asian J Nurs Educ Res [Internet]. 2016; 6(1): 48. Available from: http://dx.doi.org/10.5958/2349-2996.2016.00010.0
19. Azziz R, Nestler JE, Dewailly D. Androgen excess disorders in women: polycystic ovary syndrome and other disorders. Humana Press. 2006; 184–96.
20. Kavitha A, Veena Kiran S, Sirisha K, Babu N, Kumar S. A Short Review On Polycystic Ovary Syndrome. A Short Review On Polycystic Ovary Syndrome Innovare Journal Of Medical Science. 4(2): 6–10.
21. Kaygusuz I, Karatas OF, Kafali H, Cimentepe E, Unal D. Is polycystic ovarian syndrome a risk factor for urolithiasis? Urolithiasis [Internet]. 2013; 41(4): 361–2. Available from: http://dx.doi.org/10.1007/s00240-013-0564-9
22. Walters K. Dissecting androgens in Polycystic Ovary Syndrome (PCOS). Endocr Abstr [Internet]. 2019; Available from: http://dx.doi.org/10.1530/endoabs.63.s27.1
23. Eggers S, Hashimoto DM, Kirchengast S. An evolutionary approach to explain the high frequency of the polycystic ovary syndrome (PCOS). Anthropol Anz [Internet]. 2007; 65(2): 169–79. Available from: http://dx.doi.org/10.1127/anthranz/65/2007/169
24. Balen AH. Polycystic ovary syndrome (PCOS). Obstet Gynaecol [Internet]. 2017; 19(2): 119–29. Available from: http://dx.doi.org/10.1111/tog.12345
25. Gateva A. Assessment of polycystic ovarian syndrome patients’ perception for different cardiovascular risk factors using questionnaire. Br J Med Med Res [Internet]. 2013; 3(1): 49–57. Available from: http://dx.doi.org/10.9734/bjmmr/2013/2078
26. Nautiyal H, Imam SS, Alshehri S, Ghoneim MM, Afzal M, Alzarea SI, et al. Polycystic ovarian syndrome: A complex disease with a genetics approach. Biomedicines [Internet]. 2022; 10(3): 540. Available from: http://dx.doi.org/10.3390/biomedicines10030540
27. Derouiche S, Cheradid T, Guessoum M. Heavy metals, oxidative stress and inflammation in pathophysiology of chronic kidney disease - a review. Asian J Pharm Technol [Internet]. 2020; 10(3): 202. Available from: http://dx.doi.org/10.5958/2231-5713.2020.00033.1
28. Krishnan A, Muthusami S. Hormonal alterations in PCOS and its influence on bone metabolism. J Endocrinol [Internet]. 2017; 232(2): R99–113. Available from: http://dx.doi.org/10.1530/JOE-16-0405
29. Geller DH, Pacaud D, Gordon CM, Misra M, of the Drug and Therapeutics Committee of the Pediatric Endocrine Society. State of the art review: Emerging therapies: The use of insulin sensitizers in the treatment of adolescents with polycystic ovary syndrome (PCOS). Int J Pediatr Endocrinol [Internet]. 2011; 2011(1): 9. Available from: http://dx.doi.org/10.1186/1687-9856-2011-9
30. Grimes DA, Economy KE. Primary prevention of gynecologic cancers. Am J Obstet Gynecol [Internet]. 1995; 172(1): 227–35. Available from: http://dx.doi.org/10.1016/0002-9378(95)90125-6
31. Halperin IJ, Kumar SS, Stroup DF, Laredo SE. The association between the combined oral contraceptive pill and insulin resistance, dysglycemia and dyslipidemia in women with polycystic ovary syndrome: a systematic review and meta-analysis of observational studies. Hum Reprod [Internet]. 2011; 26(1): 191–201. Available from: http://dx.doi.org/10.1093/humrep/deq301
32. Pache TD, Fauser BC. Polycystic ovaries in female-to-male transsexuals. Clin Endocrinol (Oxf). 1993; 39(6): 702–3.
33. Mayoclinic.org. [cited 2025 Apr 24]. Available from: https://www.mayoclinic.org/diseases-conditions/pcos/symptoms-
34. Cdc.gov. [cited 2025 Apr 24]. Available from: https://www.cdc.gov/diabetes/basics/pcos.html
35. Pradnya D, Vaibhav V. The Review On:Polycystic Ovary Syndrome (PCOS). International Journal of Pharmaceutical research and Applications. 6(6): 443–8.
36. Verma A, Dhiman K. Management of PCOS: A Psychosomatic Disorder by Yoga Practice Systematic review of researches on Female infertility View project of PCOS: A Psychosomatic Disorder by Yoga Practice. Int J Innov Res Dev. 2015; 4: 216–9.
37. Naderpoor N, Shorakae S, de Courten B, Misso ML, Moran LJ, Teede HJ. Metformin and lifestyle modification in polycystic ovary syndrome: systematic review and meta-analysis. Hum Reprod Update [Internet]. 2016; 22(3): 408–9. Available from: http://dx.doi.org/10.1093/humupd/dmv063
38. Harrison CL, Lombard CB, Moran LJ, Teede HJ. Exercise therapy in polycystic ovary syndrome: a systematic review. Hum Reprod Update [Internet]. 2011; 17(2): 171–83. Available from: http://dx.doi.org/10.1093/humupd/dmq045
39. Saidunnnisa G, Begum GS, Shariff A, Ayman G, Mohammad B, Housam R, et al. Assessment of Risk Factors for development of Polycystic Ovarian Syndrome Clinical Skills-teaching made effective View project Assessment of Risk Factors for development of Polycystic Ovarian Syndrome View Project Assessment of Risk Factors for development. Int J Contemp MedRes. 2017; 4: 2454–73.
40. Lindberg S. Yoga for PCOS: Benefits and specific poses that may help [Internet]. Healthline. Healthline Media; 2020 [cited 2025 Apr 24]. Available from: https://www.healthline.com/health/yoga-for-pcos
41. Rumaisa Rashid,Suhail Ahmad Mir,Ozaifa Kareem,Tabassum Ali,Rifat Ara, Anjum Malik, Fiza Amin, G.N Bader.Taiwanese Journal of Obstetrics & Gynecology. 2022; 61: 40-50.
42. Legro RS, Arslanian SA, Ehrmann DA, Hoeger KM, Murad MH, Pasquali R, et al. Diagnosis and treatment of polycystic ovary syndrome: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab [Internet]. 2013; 98(12): 4565–92. Available from: http://dx.doi.org/10.1210/jc.2013-2350
43. Legro RS, Brzyski RG, Diamond MP. NICHD Reproductive Medicine Network. Letrozole versus clomiphene for infertility in the polycystic ovary syndrome. N Engl J Med. 2014; 317(15):119–20.
44. Rashidi S, Farajee H, Jahanbin D, Mirfardi A. Evaluation of Knowledge, Belief, and Operation of Yasouj People Towards Pharmaceutical Plants. J Med Plants. 2012; 11:177–84.
45. Omkar A, Rohan D, Nisarga V, Sokate UR, Randave PA. A Review on: Polycystic Ovarian Disorder. A Review on: Polycystic Ovarian DisorderAsian Journal of Research in Pharmaceutical Sciences. 2022; 12(3): 219–25.
46. Devade O, Londhe R, Rathod N, Kupate J, Meshram N. Ayurvedic Remedies of Covid-19. Int J Pharm Sci Rev Res [Internet]. 2021; 70(2). Available from: http://dx.doi.org/10.47583/ijpsrr.2021.v70i02.009
47. Mali KK, Sutar GV, Dias RJ, Devade OA. Evaluation of nootropicactivity of Limonia acidissima against scopolamine-induced amnesiain rats. Turk J Pharm Sci. 2021; 18(1):3–9.
48. Medicinal plants with Memory enhancing activity: review. J Pharm Adv Res. 2022; 5(2): 1452–9
49. Rathinavel T, Palanisamy M, Palanisamy S, Subramanian A, Thangaswamy S. Phytochemical 6-Gingerol – A promising Drug of choice for COVID-19. Int J Adv Sci Eng [Internet]. 2020; 6(4): 1482–9. Available from: http://dx.doi.org/10.29294/ijase.6.4.2020.1482-1489
50. Zhu J, Chen H, Song Z, Wang X, Sun Z. Effects of ginger (Zingiber officinale Roscoe) on type 2 diabetes mellitus and components of the metabolic syndrome: A systematic review and meta-analysis of randomized controlled trials. Evid Based Complement Alternat Med [Internet]. 2018; 2018: 5692962. Available from: http://dx.doi.org/10.1155/2018/5692962
51. G. Saravanan, P. Ponmurugan, M.A. Deepac, B. Senthilkumard, Anti-obesity action of gingerol: effect on lipid profile, insulin, leptin, amylase and lipase in male obese rats induced by a high-fat diet, J. Sci. Food Agric. 94 (2014)2972e2977.
52. Pournaderi PS, Yaghmaei P, Khodaei H, Noormohammadi Z, Hejazi SH. The effects of 6-Gingerol on reproductive improvement, liver functioning and Cyclooxygenase-2 gene expression in estradiol valerate – Induced polycystic ovary syndrome in Wistar rats. Biochem Biophys Res Commun [Internet]. 2017; 484(2): 461–6. Available from: http://dx.doi.org/10.1016/j.bbrc.2017.01.057
53. Patni S. Comprehensive review of medicinal plants used in treatment of migraine. Asian J Res Pharm Sci [Internet]. 2020; 10(3): 189. Available from: http://dx.doi.org/10.5958/2231-5659.2020.00036.3
54. Prashar D, Saklani S, Barshiliya Y, Sharma M, Mankotia S, Soni A. Pharma-Economical World of Herbal Antitussive- An Overview. Asian J Res Pharm Sci. 2012; 2(2): 48–51.
55. Kp Sampath Kumar D, Tripathi M. Traditional Indian Herbal Plants Tulsi and Its Medicinal Importance. Research J Pharmacognosy and Phytochemistry. 2010; 2(2): 93–101.
56. Jungbauer A, Medjakovic S. Phytoestrogens and the metabolic syndrome. J Steroid Biochem Mol Biol [Internet]. 2014; 139: 277–89. Available from: http://dx.doi.org/10.1016/j.jsbmb.2012.12.009
57. Kooti W, Moradi M, Ali-Akbari S, Sharafi-Ahvazi N, Asadi-Samani M. Damoon Ashtary-Larky. Therapeutic and pharmacological potential of Foeniculum vulgare Mill: A review. J Herb Med Pharmacol. 2015; 4(1): 1–9.
58. Gonzales GF, Córdova A, Vega K, Chung A, Villena A, Góñez C, et al. Effect of Lepidium meyenii (MACA) on sexual desire and its absent relationship with serum testosterone levels in adult healthy men. Andrologia [Internet]. 2002; 34(6): 367–72. Available from: http://dx.doi.org/10.1046/j.1439-0272.2002.00519.x
59. Silva RR, e Silva DO, Fontes HR, Alviano CS, Fernandes PD, Alviano DS. Anti-inflammatory, antioxidant, and antimicrobial activities of Cocos nucifera var. typica. BMC Complement Altern Med [Internet]. 2013; 13(1). Available from: http://dx.doi.org/10.1186/1472-6882-13-107
60. Yong JWH, Ge L, Ng YF, Tan SN. The chemical composition and biological properties of coconut (Cocos nucifera L.) water. Molecules [Internet]. 2009; 14(12): 5144–64. Available from: http://dx.doi.org/10.3390/molecules14125144
61. Soumya V, Muzib YI, Venkatesh P, Hariprasath K. GC-MS analysis of Cocus nucifera flower extract and its effects on heterogeneous symptoms of polycystic ovarian disease in female Wistar rats, Chin. Chin J Nat Med. 12: 2014677–84.
62. Baby B, Rani S, Remya K, Shebina P. Polycystic ovarian syndrome: Therapeutic potential of herbal r emedies- A review. International Journal of Herbal Medicine. 2016; 4(5): 91–6.
63. Soumya V, Muzib YI, Venkatesh P, Hariprasath K. GC-MS analysis of Cocus nucifera flower extract and its effects on heterogeneous symptoms of polycystic ovarian disease in female Wistar rats. Chin J Nat Med [Internet]. 2014; 12(9): 677–84. Available from: http://dx.doi.org/10.1016/S1875-5364(14)60103-5
64. Manoharan Y, Haridas V, Vasanthakumar KC, Muthu S, Thavoorullah FF, Shetty P. Curcumin: A wonder drug as a preventive measure for COVID19 management. Indian J Clin Biochem [Internet]. 2020; 35(3): 373–5. Available from: http://dx.doi.org/10.1007/s12291-020-00902-9
65. Alsamydai A, Jaber N. Pharmacological aspects of curcumin: review article. International Journal of Pharmacognosy E. (6): 313–26.
66. Reddy PS, Begum N, Mutha S, Bakshi V. Beneficial effect of Curcumin in Letrozole induced polycystic ovary syndrome. Asian Pac J Reprod [Internet]. 2016; 5(2): 116–22. Available from: http://dx.doi.org/10.1016/j.apjr.2016.01.006
67. Shamsi M, Nejati V, Najafi G, Pour SK. Protective effects of licorice extract on ovarian morphology, oocyte maturation, and embryo development in PCOS-induced mice: An experimental study. Int J Reprod Biomed (Yazd) [Internet]. 2020; 18(10): 865–76. Available from: http://dx.doi.org/10.18502/ijrm.v13i10.7771
68. Rao PV, Gan SH. Cinnamon: a multifaceted medicinal plant. Evid Based Complement Alternat Med [Internet]. 2014; 2014(1): 642942. Available from: http://dx.doi.org/10.1155/2014/642942
69. Wang JG, Anderson RA, Graham GM 3rd, Chu MC, Sauer MV, Guarnaccia MM, et al. The effect of cinnamon extract on insulin resistance parameters in polycystic ovary syndrome: a pilot study. Fertil Steril [Internet]. 2007; 88(1): 240–3. Available from: http://dx.doi.org/10.1016/j.fertnstert.2006.11.082
70. Dou L, Zheng Y, Li L, Gui X, Chen Y, Yu M, et al. The effect of cinnamon on polycystic ovary syndrome in a mouse model. Reprod Biol Endocrinol [Internet]. 2018; 16(1): 99. Available from: http://dx.doi.org/10.1186/s12958-018-0418-y
71. Shirani K, Hassani FV, Azar-Khiavi KR, Moghaddam ZS, Karimi G. Determination of methanol in Iranian herbal distillates. J Complement Integr Med [Internet]. 2016; 13(2): 123–7. Available from: http://dx.doi.org/10.1515/jcim-2015-0041
72. Roblová V, Bittová M, Kubáň P, Kubáň V. Capillary electrophoresis fingerprinting and spectrophotometric determination of antioxidant potential for classification of Mentha products. J Sep Sci [Internet]. 2016; 39(14): 2862–8. Available from: http://dx.doi.org/10.1002/jssc.201600235
73. Sadeghi Ataabadi M, Alaee S, Bagheri MJ, Bahmanpoor S. Role of essential oil of Mentha spicata (spearmint) in addressing reverse hormonal and folliculogenesis disturbances in a polycystic ovarian syndrome in a rat model. Adv Pharm Bull [Internet]. 2017; 7(4): 651–4. Available from: http://dx.doi.org/10.15171/apb.2017.078
74. Mehraban M, Jelodar G, Rahmanifar F. A combination of spearmint and flaxseed extract improved endocrine and histomorphology of ovary in experimental PCOS. J Ovarian Res [Internet]. 2020; 13(1): 32. Available from: http://dx.doi.org/10.1186/s13048-020-00633-8
75. Sahu P, Giri D, Singh R, Pandey P. Therapeutic and Medicinal Uses of and lt; i>Aloe vera </i>: A Review. Pharmacology & Pharmacy. 2013; 4(8): 599–610.
76. Ojha M, Meshram N, Singh A, Alexander A, Ajazuddin, Sharma M. The scope of herbal plants as the source of contraceptive values in males. Asian J Res Pharm Sci [Internet]. 2015; 5(1): 59. Available from: http://dx.doi.org/10.5958/2231-5659.2015.00010.7
77. Maharjan R, Nagar PS. Effect of Aloe barbadensis Mill.formulation on Letrozole induced polycystic ovarian syndrome rat model. J Ayurveda Integr Med. 2010; 1(4): 273–9.
78. Kamble AV, Dhamane SP, Kulkarni AS. Review on effects of herbal extract for the treatment of Polycystic Ovarian Syndrome (PCOS). Plant Archives. 2020; 20:1189–95.
79. Blumenthal M, Goldberg A, Brinckmann J. Herbal Medicine: Expanded Commission E Monographs. Austin, TX; Newton, MA: American Botanical Council; 2000.
80. Bashtian MH, Emami SA, Mousavifar N, Esmaily HA, Mahmoudi M, Poor AHM. Evaluation of fenugreek (Trigonella Foenum- graceum L.), effects seeds extract on insulin resistance in women with polycystic ovarian syndrome. Iranian J Pharm Res: IJPR. 2013; 12.
81. Harris RE, Chlebowski RT, Jackson RD, Frid DJ, Ascenseo JL, Anderson G, et al. Breast cancer and nonsteroidal anti-inflammatory drugs: prospective results from the Women’s Health Initiative. Cancer Res. 2003; 63(18): 6096–101.
82. Liu Y, Kakani R, Nair MG. Compounds in functional food fenugreek spice exhibit anti-inflammatory and antioxidant activities. Food Chem [Internet]. 2012; 131(4): 1187–92. Available from: http://dx.doi.org/10.1016/j.foodchem.2011.09.102
83. Bashtian MH, Emami SA, Mousavifar N, Esmaily HA, Mahmoudi M, Poor AHM. Evaluation of fenugreek (Trigonella Foenum- graceum L.), effects seeds extract on insulin resistance in women with polycystic ovarian syndrome. Iranian J Pharm Res: IJPR. 2013; 12.
84. Kaur R, Kaur H, Singh AD. Glycyrrhiza glabra: A phytopharmacological review. IJPSR. 2013; 4(7): 2470–7.
85. Kataria R, Singh G. Pharmacological activities on glycyrrhiza glabra -A review. Asian J Pharm Clin Res. 2013; 6(1): 5–7.
86. Sharma I, Parashar B, Kumar Dhamija H, Sharma R. An Ayurvedic Arena for Hypertension Treatment. Asian J Pharm Res. 2012; 2(2):54–8.
87. Yang H, Kim H, Pyun B, Lee H. Licorice ethanol extract improves symptoms of polycystic ovary syndrome in Letrozole-induced female rats. Integrative Medicine Research. 2018; 7(3): 264–70.