Rahul Jodh, Mukund Tawar, Aparna Kachewar, Vishal Mahanur, Yash Sureka, Virendra Atole
Rahul Jodh*, Mukund Tawar, Aparna Kachewar, Vishal Mahanur, Yash Sureka, Virendra Atole
Department of Pharmacology, P. R. Pote Patil College of Pharmacy, Amravati-444604.
Volume - 12,
Issue - 1,
Year - 2022
The liver assumes a significant part in keeping up with the metabolic capacity and discharge of poisons from the body. A physical issue or liver brokenness brought about by the utilization of poisonous synthetics, over-the-top liquor and microorganisms bring about a difficult condition called hepatotoxicity. Madhuca longifolia having a place with Sapotaceae family is found to have pharmacological properties in the treatment of different disorders. Madhuca longifolia is likewise considered a therapeutic tree also, is helpful for outside application in treating skin infections, stiffness, migraine, persistent clogging, heaps, hemorrhoids, and ethno clinical properties like antibacterial, anxiolytic qualities, anticancer, hepatoprotective, antiulcer, antihyperglycemic, pain-relieving exercises, and so on. Leaves of mahua are utilized in the treatment of dermatitis, wound mending, anti-burn, bone crack, anthelminthic, emollient, skin illness, stiffness, and cerebral pain. The flowers are used as a tonic, pain-relieving, and diuretic; bark for an ailment, persistent bronchitis, and diabetes mellitus and leaves as an expectorant and constant bronchitis and Cushing's sickness. In this review we make a compilation focused on the synonyms, botanical description, phytochemicals, pharmacological activity, and medicinal uses of Madhuca longifolia.
Cite this article:
Rahul Jodh, Mukund Tawar, Aparna Kachewar, Vishal Mahanur, Yash Sureka, Virendra Atole. Pharmacological Review on Madhuca longifolia. Asian Journal of Research in Pharmaceutical Sciences. 2022; 12(1):29-6. doi: 10.52711/2231-5659.2022.00006
Rahul Jodh, Mukund Tawar, Aparna Kachewar, Vishal Mahanur, Yash Sureka, Virendra Atole. Pharmacological Review on Madhuca longifolia. Asian Journal of Research in Pharmaceutical Sciences. 2022; 12(1):29-6. doi: 10.52711/2231-5659.2022.00006 Available on: https://ajpsonline.com/AbstractView.aspx?PID=2022-12-1-6
1. Verma SC, Vashishth E, Singh R, Kumari A, Meena AK, Pant P, Bhuyan GC, Padhi MM. A review on parts of Albizia lebbeck (L.) Benth. used as ayurvedic drugs. Research Journal of Pharmacy and Technology. 2013;6(11):1307-13. DOI: 10.5958/0974-360X
2. Ekka NR, Namdeo KP, Samal PK. Standardization strategies for herbal drugs-An overview. Research Journal of Pharmacy and Technology. 2008;1(4):310-2. DOI: 10.5958/0974-360X
3. Shrivastava A, Jain R, Agrawal RK, Ahirwar D. Clinical trial of herbal drugs and products in India: Past and current status and critical issues. Research Journal of Pharmacy and Technology. 2008;1(2):69-74. DOI: 10.5958/0974-360X
4. Simha GV, Kumar MA, Rajesh S, Panda P, Rao MM. Evaluation of physicochemical parameters of Imperata cylindrica (Linn) beauv root used in ayurvedic formulations. Research Journal of Pharmacy and Technology. 2012; 5(10): 1352-5. DOI: 10.5958/0974-360X
5. Nayak A, Sajini RJ, Padmavati D, Karthik R. Chemistry and medicinal properties of Coscinium fenestratum (Gaertn.) Colebr (Tree Turmeric). Research Journal of Pharmacy and Technology. 2012;5(2):198-202. DOI: 10.5958/0974-360X
6. Meena AK, Mangal AK, Simha GV, Rao MM, Panda P, Singh H, Padhi MM, Babu R. Evaluation of Phamacognostic and Physicochemical Parameters of Trikatu churna-an Ayurvedic Classical Drug. Research Journal of Pharmacy and Technology. 2011;4(12):1882-4.
7. Banu UK, Vadivu R, Suresh AJ. Pharmacognostical Standardization of Roots of Premna serratifolia Linn. Research Journal of Pharmacy and Technology. 2009;2(1):180-5.
8. Shah JS, Goyal RK. Pharmacoepidemiological Study of Learning and Memory Enhancing Medicines: A Comparison between Herbal and Allopathic Formulations. Research Journal of Pharmacy and Technology. 2010;3(1):146-50.
9. Mendhe BB, Gupta P, Mhaske S, Shrivastava S. Evaluation of Ayurvedic Marketed Formulations Asava's and Arista's. Research Journal of Pharmacy and Technology. 2010;3(3):915-6.
10. Bhaskar VH, Sangameswaran B, Balakrishnan N, Panda AB, Raj NR, Sathish A. Screening of Analgesic and Anti-inflammatory Activity of Hydroalcohol Extract of Sida (Indian) Species Root. Research Journal of Pharmacy and Technology. 2008;1(3):287-9.
11. Malviya V, Manekar S. Design, Development and Evaluation of Aceclofenac and Curcumin Agglomerates by Crystallo Co-Agglomeration Technique. Research Journal of Pharmacy and Technology. 2021 Mar 1;14(3):1535-41. DOI: 10.5958/0974-360X.2021.00272.9
12. Singh H, Mani M. Evaluation of anxiolytic activity of hydro-alcoholic extract of Madhuca longifolia leaves. J. Nat. Prod. Plant Resources. 2014;4(1):19-22.
13. Patel, Pushpendra Janghel, Vandana Chandel, Saket Sahu, Jyoti. (2019). Madhuca indica (Mahua) -Pharmaceutical, Nutraceutical and Economical Importance for Tribal People of Chhattisgarh State. 9. 16-28.
14. One. V. C, Ganesh D, Shrinivas S. Study of the immunosuppressive activity of methanolic extract of Madhuca longifolia (Koenig). Oriental Pharmacy and Experimental Medicine [Internet]. 2010 Sep 30;10(3):150–4. DOI: 10.4103/1995-7645.223528
15. Trivedi VB, Kazmi SM, Kazmi SN. Comparative bacterial activity of two angiosperms. Bulletin of the Botanical Society University of Saugar. 1980.
16. Khan Salehin and Zahan Dilara. Anti hyperglycemic Activity Studies with Methanol Extract of Madhuca indica J.F. Gmel. Leaves and Paederia Foetida L. Stem in Mice. Advance in natural and applied sciences. 2011; 5: 122-126.
17. RD G. Anti-inflammatory, anti-ulcer and hypoglycaemic activities of ethanolic and crude alkaloid extracts of Madhucaindica (Koenig) Gmelin seed cake. Oriental Pharmacy and Experimental Medicine. 2007;7(2):141-9.
18. Prashanth S, Kumar AA, Madhu B, Kumar YP, Prashanth S. Antihyperglycemic and antioxidant activity of ethanolic extract of Madhuca longifolia bark. International Journal of Pharmaceutical Sciences Review and Research. 2010;5(3):89-94
19. Kalaivani M, Jegadeesan M. Evaluation of antiulcer activity of ethanolic extract of Madhuca longifolia flowers in experimental rats. Int J Sci Res Publication. 2013;3(6):1-7
20. Gaikwad RD, Ahmed ML, Khalid MS, Swamy P. Anti-inflammatory activity of Madhuca longifolia seed saponin mixture. Pharmaceutical Biology. 2009 Jul 1;47(7):592-7.
21. Malviya V. Preparation and Evaluation of Emulsomes as a Drug Delivery System for Bifonazole. Indian Journal of Pharmaceutical Education and Research. 2021 Jan 1;55(1):86-94.
22. Patel PK, Sahu J. Madhucaindica: review on hepatoprotective mechanism and other medicinal uses. Glob J Pharm Res. 2012; 1:1330-8.
23. Jana GK, Gupta A, Soni D, Debnath S, Panda S. Evaluation Of Pharmacological Potentials of Methanolic Leaf Extract of Madhucalongifolia (Sopteacae) Against Pyrexia. Journal Of Pharmacy Research. 2011;4(4):1298-9.
24. Jha D, Mazumder PM. Biological, chemical and pharmacological aspects of Madhuca longifolia. Asian Pacific Journal of Tropical Medicine. 2018 Jan 1;11(1):9.
25. Odili VU, Akpe AI, Arigbe-Osula ME, Igbinaduwa PO. Antioxidant and hepatoprotective activity of Madhuca longifolia (koenig) bark against CCl4-induced hepatic injury in rats: in vitro and in vivo studies. Research Journal of Pharmaceutical Biological and Chemical Sciences. 2010;1(1):1-0.
26. Roy SP, Kannadasan T, Gupta R. Screening of hepatoprotective activity of Madhuca longifolia bark on D-Galactosamine induced hepatotoxicity in rats. Biomedical Research (0970-938X). 2015 Apr 1;26(2).
27. Patel, M. also, Naik, S.N. (2010). Blossoms of Madhuca indica J. F. Gmel.: present status and future points of view. Indian Journal of Natural Products and Resources, Vol. 1 No. 4, pp. 438-443
28. Bakhara, C.K., Bal, L.M., Pal, U.S., Sahoo, N.R. what's more, Panda, M.K. (2016), "Post-collect practices and worth expansion of Mahua (Madhuca longifolia) blossom in Odisha", Agricultural Engineering Today, Vol. 40 No. 4, pp. 22-28.
29. Behera, S., Mohanty, R.C. furthermore, Ray, R.C. (2012), "Natural chemistry of post-collect deterioration of mahula (Madhuca latifolia L.) blossoms: changes in all out sugar, ascorbic corrosive, phenol and phenylalanine alkali lyase action", Archives of Phytopathology and Plant Protection, Vol. 45 No. 7, pp. 846-855.
30. Amia, E. furthermore, Ekka, N. (2014), "Madhuca longifolia var. latifolia: a significant therapeutic plant utilized by clans of North-East piece of Chhattisgarh", Online International Interdisciplinary Research Journal, Vol. 4, pp. 227-231
31. Awasthi, Y.C., Bhatnagar, S.C. also, Mitra, C.R. (1975), "Chemurgy of sapotaceous plants: Madhuca types of India", Economic Botany, Vol. 29 No. 4, pp. 380-389.
32. Gupta, A., Chaudhary, R. furthermore, Sharma, S. (2012), "Likely uses of Mahua (Madhuca indica) biomass", Waste and Biomass Valorization, Vol. 3 No. 2, pp. 175-189
33. Sinha, J., Singh, V., Singh, J. what's more, Rai, A.K. (2017), "Phytochemistry, ethnomedical utilizations and future possibilities of Mahua (Madhuca longifolia) as a food: a survey", Journal. Nutr. Food Science, Vol. 7, p. 573.
34. Chand, S. also, Mahapatra, S.N. (1983), "Creation of sugar syrup from Mahua (Madhuca latifolia) blossoms", Research and Industry
35. Abhyankar, V.S. What's More, Narayana, N. (1942), "Reports on arrangement of sugar syrup from dry Mahua blossoms which can be further use as a sweeting starter note on the readiness of syrup from Mahua blossoms", in Poona AgricColl Mage, Vol. 33, pp. 168-172
36. Mishra, B.K., Jain, N.K., Kumar, S. also, Sharma, K.C. (2013), "Capacity solidness of prepared to-serve drink from Mahua (Madhuca indica) blossoms", Indian Journal of Horticulture, Vol. 70 No. 3, pp. 459-462
37. Patel, M., Jaiswal, S., Naik, B., Naik, M., Saxena, D. also, Naik, S.N. (2016), "Improvement of cancer prevention agent rich refreshment from Mahua (Madhuca indica) and amla (Emblica officinalis)", Journal of Scientific and Industrial Research, Vol. 75, pp. 35-39
38. Sinha, J., Singh, V., Singh, J. what's more, Rai, A.K. (2017),"Phytochemistry, ethnomedical utilizations and future possibilities of Mahua (Madhuca longifolia) as a food: a survey", Journal. Nutr. Food Science, Vol. 7, p. 573
39. Soni, S. what's more, Dey, G. (2013), "Studies on esteem added maturation of Madhuca latifolia blossom and it's anything but a nutrabeverage", International Journal of Biotechnology and Bioengineering Research, Vol. 4 No. 3, pp. 215-226
40. Singh, V., Kumar, S., Singh, J. Rai, A.K. (2018), "Fluffy rationale tangible assessment of cupcakes created from the Mahua bloom (Madhuca longifolia)", International Journal of Emerging Technologies and Innovative Research, Vol. 5 No. 1, pp. 411-421
41. Dixit, A. also, Ravat, P. (2017), "Advancement and assessment of gluten free bread rolls by fuse of Mahua powder as regular sugar", in Recent Trends in Agriculture, Food Science, Forestry, Horticulture, Aquaculture, Animal Sciences, Biodiversity, Ecological Sciences and Climate Change Proceedings of the worldwide gathering in New Delhi India, 2017, KrishiKanti, New Delhi, pp. 82-88
42. Adhikari, S. also, Adhikari, J. (1989), "Sal olein and Mahuaolein for direct palatable use", Journal of the American Oil Chemists' Society, Vol. 66 No. 11, pp. 1625-1630
43. Malavade, D.M. also, Jadhav, B.L. (2000), "Liquor creation from Madhuca indica blossoms", Trends Life Sci, Vol. 15, pp. 59-65
44. Sinha J, Singh V, Singh J, Rai AK. Phytochemistry, ethnomedical uses and future prospects of Mahua (Madhuca longifolia) as a food: a review. J. Nutr. Food Sci. 2017;7:573.Kalaivani, M. furthermore, Jegadeesan, M. (2013),"Antimicrobial action of alcoholic concentrate of leaves and blossoms of Madhuca longifolia", International Journal of Scientific and Research Publication, Vol. 3 No. 5. DOI: 10.4172/2155-9600.1000573
45. Patel, M. Naik, S.N. (2010), "Blossoms of Madhuca indica J. F. Gmel.: present status and future viewpoints", Indian Journal of Natural Products and Resources, Vol. 1 No. 4, pp. 438-443
46. Saha NK, Singh BK. Mahua Flower Agar Medium-A New, Natural And Antibacterial Culture-Medium FOR Fungi. National Academy Science Letters-India. 1991 Sep 1;14(9):359-61.
47. Mishra, Alok Poonia, Amrita. (2019). Mahua (Madhuca longifolia) flowers: review on processing and biological properties. Nutrition and Food Science. 49. 10.1108/NFS-12-2018-0358.
48. Wakte, K.V., Kad, T.D., Zanan, R.L. furthermore, Nadaf, A.B. (2011), "Component of 2acetyl1 pyrroline biosynthesis in Bassia latifolia Roxb. blossoms", Physiology and Molecular Biology of Plants : An International Journal of Functional Plant Biology, Vol. 17 No. 3, pp. 231-237. https://doi.org/10.1007/s12298-011-0075-5
49. Patil, M.P., Singh, R.D., Koli, P.B., Patil, K.T., Jagdale, B.S., Tipare, A.R. also, Kim, G.D. (2018
50. Antibacterial capability of silver nanoparticles orchestrated utilizing Madhuca longifolia bloom separate as a green asset", Microbial Pathogenesis, Vol. 121, pp. 184-189. DOI: 10.1016/j.micpath.2018.05.040
51. Purohit R, Singh SK, Shaban A, Nautiyal R, Purohit MC, Verma SK. Immuno-modulatory activity of Madhuca longifolia. Der Pharmacia Sinica 2012; 3 (1):153-155.
52. Roy SP, Shirode D, Tushar P, Shastry CS, Gheewala N, Goutam S, Ramachandra S, Rajendra SV. Antioxidant and hepatoprotective activity of Madhuca longifolia (Koenig) bark against CCl - induced hepatic injury in rats: and In vitro In vivo studies. Research Journal of Pharmaceutical, Biological and Chemical Sciences 2010; 1:1-10
53. Malviya VR, Tawar MG. Preparation and Evaluation of Oral Dispersible Strips of Teneligliptin Hydrobromide for Treatment of Diabetes Mellitus. International Journal of Pharmaceutical Sciences and Nanotechnology. 2020 Jan 31;13(1):4745-52. https://doi.org/10.37285/ijpsn.2020.13.1.2
54. Malviya V, Thakur Y, Gudadhe SS, Tawar M. Formulation and evaluation of natural gum based fast dissolving tablet of Meclizine hydrochloride by using 3 factorial design 2. Asian Journal of Pharmacy and Pharmacology. 2020;6(2):94-100.
55. Malviya V, Ladhake V, Gajbiye K, Satao J, Tawar M. Design and Characterization of Phase Transition System of Zolmitriptan Hydrochloride for Nasal Drug Delivery System. International Journal of Pharmaceutical Sciences and Nanotechnology. 2020 May 31;13(3):4942-51. https://doi.org/10.37285/ijpsn.2020.13.3.8
56. Seshagiri M, Gaikwad RD, Paramjyothi S, Jyothi KS, Ramchandra S (2007) Antiinflammatory, anti-ulcer and hypoglycemic activities of ethanolic and crude alkaloid extract of Madhucaindica (Koenig) Gmel in seed cake. Orient Pharm Exp Med 7: 141-149. https://doi.org/10.3742/OPEM.2007.7.2.141
57. Ramchandra D, Gaikwad MD, Liyaqat AMD, Swamy SKP (2009) Antiinflammatory movement of Madhucalongifolia seeds saponin blend. PharmaceutBiol 47: 592-597.
58. Malviya VR, Pande SD. Road CKN. Preparation ad Evaluation of Zolmitriptan Hydrochloride Lozenge. J Pharma Res. 2019;8(8):624-9. DOI/10.5281/zenodo.3382177.svg
59. Indian Pharmacopoeia (1996) Controller of Publication Government of India New Delhi, India, pp: A53-A54.
60. Malviya VR, Pande SD, Bobade NN. Preparation and Evaluation of Sustained Release Beads of Zolmitriptan Hydrochloride. Research Journal of Pharmacy and Technology. 2019;12(12):5972-6. 10.5958/0974-360X.2019.01037.0