Pedalium murex Linn (belongs to the Pedaliaceae family) commonly referred to as Large Caltrops and Gokhru (India) is a shrub located in the southern part of India's Deccan region, and in parts of Ceylon. The phytochemicals found in the Pedalium murex L. includes ursolic acid, caffeic acid, quercetin, various classes of fatty acid (tritriacontane, tetratriacontanyl riacontanoic acid, nonacosane and heptatriacontan-4-one) and amino acids (tyrosine, threonine, aspartic acid, glycine, histidine and glutamic acid). Phytochemically the P. murex is famous for the containing desirable amounts of diosgenin and vanillin that are considered to be an essential source and useful for the synthesis of steroidal contraceptive drugs and isatin alkaloids as starting material. The Pedalium murex L. have pharmacological activities like antiulcerogenic, antioxidant, nephroprotective, hypolipidemic, aphrodisiac, antibacterial activities. This review is a compilation of knowledge gathered from the research papers published and review the phytochemical and pharmacological aspects of P. murex.
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9. Giribabu K, Pushpa S, Latha YJP, Ranganayakulu D, Rajasekhar KK, Haribabu R. Available online through Effect of leaves of Pedalium murex linn. against aspirin induced gastric ulcers in rats. 2011;4(3):882-883.
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11. Sangeetha G, Vidhya R; In vitro anti-inflammatory activity of different parts of Pedalium murex (L.). International Journal of Herbal Medicine. 2016;4(3):31-36.
12. Davidraj BPC, Ramasubramaniaraja NTR; Available online through Evaluation of Anti-Inflammatory Activity of Methanol Extract of Abutilon indicum And Pedalium murex- A Comparative Study. 2010;3(10):2425-2426.
13. Muruganantham Sermakkani; Evaluation of Phytochemical and Antibacterial Activity of Pedalium Murex Linn Root; Internation al Research Journal of Pharmacy; 2011;2(3):131-134.
14. Srinivas P, Reddy S.R.; Screening for Antibacterial Principle and Activity of Pedalium murex Linn. Proceedings of the National Academy of Sciences India Section B - Biological Sciences. 2014;84(4):1083-1090.
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17. Madhu Babu A, Srinivas P, Venkateshwarulu L, Anil Kumar C. Antioxidant activity of Pedalium murex fruits in carbon tetra chloride- induced hepatopathy in rats. International Journal of Pharma and Bio Sciences. 2011;2(1):622-628.
18. Balamurugan G, Muralidharan P, Polapala S. Aphrodisiac activity and curative effects of Pedalium murex (L.) against ethanol-induced infertility in male rats. Turkish Journal of Biology. 2010;34(2):153-163.
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20. Balasubramanian MM, Muralidharan P, Balamurugan G. Anti hyperlipidemic activity of Pedalium murex (linn.) fruits on high fat diet fed rats. International Journal of Pharmacology. 2008;4(4):310-313.
21. Kaleeswaran B, Ramadevi S, Murugesan R, Srigopalram S, Suman T, Balasubramanian T. Evaluation of anti-urolithiatic potential of ethyl acetate extract of Pedalium murex L. on struvite crystal (kidney stone). Journal of Traditional and Complementary Medicine. 2019;9(1):24-37.
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24. Shelke TT, Kothai R, Adkar PP, et al. Nephroprotective Activity of Ethanolic Extract of dried fruits of Pedalium murex Linn. Journal of Cell and Tissue Research. 2009;9(1):1687-1690.
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27. Jaideep Singh, Shivalinge Gowda KP, Shrishailappa Badami, Rahul Akuskar, Nagarjan Tukuru.; Scrutinizing the Fresh Juice of Leaves of Pedalium murex for the Antiulcer Activity in rats. Research J. Pharm. and Tech.; 2009; 2(1); 191-194.
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29. Sridhar N, Kiran B, Raghavendra M, Prasad M, Kanthal L, Satyavathi K.; Comparative anthelmintic evaluation of Glycosmis mauritiana and Pedalium murex L. roots; Research J. Pharmacology and Pharmacodynamics; 2012;4(3):185-187.
30. Gomathi S, Shanmuga Sundaram R, Vijayabaskaran M, Kannan C, Sambathkumar R.; Pedalium murex linn leaves against LPS-induced oxidative stress, anxiety and depression behavioural alterations in rats. Res. J. Pharm Technol. 2017; 10(5); 1333-1338.
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