Author(s): Harikrishnan.V, Sreejith. M, Elthose. M.J, Akash Marathakam

Email(s): hariforjournal@gmail.com

DOI: 10.5958/2231-5659.2017.00006.6   

Address: Harikrishnan.V1, Sreejith. M2, Elthose. M.J1, Akash Marathakam3
1Mookamabika College of Pharmaceutical Science and Research, Muvatupuzha Kerala, India
2Nazareth College of Pharmacy, Thiruvalla, Kerala, India
3National College of Pharmacy Kozhikode, Kozhikode, Kerala, India
*Corresponding Author

Published In:   Volume - 7,      Issue - 1,     Year - 2017


ABSTRACT:
Gelucire is the group of vehicle got from blends of mono-, di-and tri-glycerides with PEG esters of unsaturated fats. They have a wide assortment of utilization in pharmaceutical definitions. These are utilized as a part of the arrangement of quick release and maintained release of drug in sustained manner. Keeping in mind the end goal to build the bioavailability of medications, the residence time of the orally controlled dose frame in the upper GIT should be drawn out. The principle ways to deal with drawing out the gastric residence time of pharmaceutical dosage form incorporates thickness control conveyance framework, which drift on gastric liquid and a resource for treat Diabetes sort II. Gastro retentive strong scattering could be accomplished of ineffectively solvent medication Glibenclamide with the assistance of polyethylene glycol and Gelucire 50/13. Then again managed discharge gastroretentive multiparticulates of metformin hydrochloride could be accomplished utilizing Gelucire 39/01 and 43/01 grades. Further both details can be investigated individual and also in mix for enhanced bioavailability by their pharmacokinetic and pharmacodynamic assessment in wistar rats.


Cite this article:
Harikrishnan.V, Sreejith. M, Elthose. M.J, Akash Marathakam. Gelucire: An Optional Innovative Tool for both Sustained and Fast Release of Drugs in Treating Diabetes Mellitus Type II Disease. Asian J. Res. Pharm. Sci. 2017; 7(1): 33-37. doi: 10.5958/2231-5659.2017.00006.6

Cite(Electronic):
Harikrishnan.V, Sreejith. M, Elthose. M.J, Akash Marathakam. Gelucire: An Optional Innovative Tool for both Sustained and Fast Release of Drugs in Treating Diabetes Mellitus Type II Disease. Asian J. Res. Pharm. Sci. 2017; 7(1): 33-37. doi: 10.5958/2231-5659.2017.00006.6   Available on: https://ajpsonline.com/AbstractView.aspx?PID=2017-7-1-6


Recomonded Articles:

Author(s): Mohd. Yaqub Khan, Maryada Roy, Brijesh Kumar Saroj, Sudhakar Dubey, Vineet Kumar Sharma

DOI: 10.5958/2231-5659.2015.00019.3         Access: Open Access Read More

Author(s): Priyanka M. Salve, Shital V. Sonawane, Mayuri B. Patil, Rajendra K. Surawase

DOI: 10.52711/2231-5659.2021.00037         Access: Open Access Read More

Author(s): Manukondakeerthi, Lakshmiprasanna. J, Santhosh aruna M, Rama Rao N

DOI:         Access: Open Access Read More

Author(s): Vishal Kumar, Attish Bhardwaj, Navdeep Singh, Kamya Goyal, Shammy Jindal

DOI: 10.52711/2231-5659.2021.00038         Access: Open Access Read More

Author(s): Amol P. Suryawanshi, Dattatraya M. Shinkar, R.B. Saudagar.

DOI: 10.5958/0975-4377.2015.00013.0         Access: Open Access Read More

Author(s): Dibyajyoti Saha, Milan Hait, Mayukh Jana, Suprodip Mandal, Utpal Jana

DOI:         Access: Open Access Read More

Author(s): Namdeo Shinde, Nagesh Aloorkar, Ajit Kulkarni, Bhaskar Bangar, Suyog Sulake, Pratik Kumbhar

DOI:         Access: Open Access Read More

Author(s): Pradnya M. Khandagale, Bhushan Bhairav, R. B. Saudagar

DOI: 10.5958/2231-5659.2016.00038.2         Access: Open Access Read More

Author(s): Saudagar R. B., Sarika V. Khandbahale

DOI: 10.5958/2231-5659.2017.00005.4         Access: Open Access Read More

Author(s): Aprajita Shifali, Pravin Kumar, Vinay Pandit

DOI: 10.5958/2231-5659.2021.00012.6         Access: Open Access Read More

Author(s): Rajashri R. Kulkarni, Dipti G. Phadtare, Ravindra B. Saudagar

DOI: 10.5958/2231-5659.2016.00019.9         Access: Open Access Read More

Author(s): Pankaj R. Dhapake, Chauriya C.B., Umredkar R.C.

DOI: 10.5958/2231-5659.2017.00001.7         Access: Open Access Read More

Author(s): Girishchandra R. Mandake, Indrajit S. Patil, Omkar A Patil, Manoj M. Nitalikar, Shriniwas K Mohite

DOI: 10.5958/2231-5659.2018.00012.7         Access: Open Access Read More

Author(s): Vrushali R. Kadam, M. P. Patil, Vrushali V. Pawar, Sanjay Kshirsagar

DOI: 10.5958/2231-5659.2017.00030.3         Access: Open Access Read More

Author(s): Viral Patel

DOI:         Access: Open Access Read More

Author(s): S. S. Shuka, Bina Gidwani, R. Pandey, S. P. Rao, V. Singh, Amber Vyas

DOI:         Access: Open Access Read More

Author(s): Surekha Baghel, Bina Gidwani, Chanchal Deep Kaur

DOI: 10.5958/2231-5659.2017.00009.1         Access: Open Access Read More

Author(s): Kadam T.V. , Darekar A.B., Gondkar S.B., Saudagar R.B.

DOI: 10.5958/2231-5659.2015.00014.4         Access: Open Access Read More

Author(s): Sana Banu, Syeda Ayesha Farheen

DOI: 10.5958/2231-5659.2019.00015.8         Access: Open Access Read More

Asian Journal of Research in Pharmaceutical Sciences (AJPSci) is an international, peer-reviewed journal, devoted to pharmaceutical sciences....... Read more >>>

RNI: Not Available                     
DOI: 10.52711/2231-5659 


Recent Articles




Tags