Author(s): Swapnil S Chopade, Esther Gaikwad, Avdhut Jadhav, Nikhil Patil, Santosh Payghan

Email(s): swapnilchopade.tkcp@gmail.com

DOI: 10.5958/2231-5659.2020.00046.6   

Address: Swapnil S Chopade1*, Esther Gaikwad1, Avdhut Jadhav2, Nikhil Patil3, Santosh Payghan4
1Department of Pharmaceutics, Tatyasaheb Kore College of Pharmacy, Warananagar, Panhala, Kolhapur, Maharashtra, India 416114.
2Department of Pharmaceutics, Ashokrao Mane College of Pharmacy, Peth Vadgaon, Kolhapur, Maharashtra, India 416112.
3Vasantidevi Patil Institute of Pharmacy, Kodoli, Panhala, Kolhapur, Maharashtra, India 416114.
4Principal Vasantidevi Patil Institute of Pharmacy, Kodoli, Panhala, Kolhapur, Maharashtra, India 416114.
*Corresponding Author

Published In:   Volume - 10,      Issue - 4,     Year - 2020


ABSTRACT:
The aim of this investigation is to formulate and characterize FDTs Formulations for physicochemical properties like Differential Scanning Calorimetry (DSC) and Fourier Transformed Infra Red Spectroscopy (FTIR) characterized the interactive powder sample mixture. Rapidly disintegrating tablets were formulated by direct compression method. For disintegration time, hardness, friability, tensile strength, weight variation and in vitro release studies, the Fast disintegrating tablets have been evaluated. During the FDT process, FTIR indicated that there was no chemical reaction between the two species (drug and excipients). In all concentrations tested in the fast dissolving tablet formulation, the interactive mixture was found to be effective. In the case of interactive mixing, disintegration time (DT) of less than 30 seconds was observed. In pharmaceutical applications, FDTs can be used as a better option.


Cite this article:
Swapnil S Chopade, Esther Gaikwad, Avdhut Jadhav, Nikhil Patil, Santosh Payghan. Formulation and Evaluation of Fast Disintegrating Tenoxicam Tablets and The Comparison with Marketed Product. Asian J. Res. Pharm. Sci. 2020; 10(4):257-263. doi: 10.5958/2231-5659.2020.00046.6


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