Author(s):
Sreelakshmi K.P., Aleeda K.A., Febina K.S., Hiba mumthas K.P., Shahana Sherin K.T., Staicy Sebastian
Email(s):
sreelakshmisreelakshmikp3288@gmail.com
DOI:
10.52711/2231-5659.2025.00008 
Address:
Sreelakshmi K.P.1*, Aleeda K.A.2, Febina K.S.2, Hiba mumthas K.P.2, Shahana Sherin K.T.2, Staicy Sebastian2
1Assistant Professor, Department of Pharmacognosy and Phytochemistry, Nehru College of Pharmacy, Pampady, Thiruvilwamala, Thrissur, Kerala, India.
2Student, Nehru College of Pharmacy, Pampady, Thiruvilwamala, Thrissur, Kerala, India.
*Corresponding Author
Published In:
Volume - 15,
Issue - 1,
Year - 2025
ABSTRACT:
Around the world, traditional medicines are crucial to health care. Pertaining to the Lamiaceae family is Gmelina arborea Roxb. Any plant that is used medicinally requires thorough research before use, so the current study was conducted to establish pharmacognostical and physicochemical standards for Gambhari leaf. This was done to prevent the admixture of other drugs with the plant and to ensure its therapeutic efficacy. Due to its extensive medical characteristics, this medicinal plant has been highly esteemed for ages. An analysis of pharmacognostic data reveals the amount of moisture, total ash value, water, and acid insoluble value. Alcoholic and aqueous extracts, as well as their extractive values. Evaluated at the microscopic and macro levels. Vein islet number, vein termination variety, and stomatal index are only a few of the leaf constants that have been provided. Alkaloids, sugars, coumarins, steroids, and tannins were discovered through phytochemical analysis. Gambhari's roots, fruits, and leaves have a wide range of medicinal uses; as a result, it has historically been used as an anti-inflammatory, anthelmintic, anti-microbial, anti-diabetic, anti-aging, analgesic, diuretic, hepato-protective, and anti-epileptic agent. It has been reported to have uses for treating hypertension, bone fractures, and regenerating -cells. Lignans, iridoid glycoside, flavonoids, flavones, flavone glycoside, and steroids are some of G. arborea's primary chemical components. In the Sothahara, Dahaprasamana, and Virecanopaga mahakasaya, Acharya Charaka mentions the Gambhari plant. He also described its fruit as the best among Rakta-sangrahaka and Raktapittahara. This article gives all the information you need to know about its historical literature, general introduction, and the therapeutic benefits of its roots, leaves, flowers, and fruits. Bark, as well as current pharmaceutical research.
Cite this article:
Sreelakshmi K.P., Aleeda K.A., Febina K.S., Hiba mumthas K.P., Shahana Sherin K.T., Staicy Sebastian. Review on Gmelina arborea Roxb (Lamiaceae). Asian Journal of Research in Pharmaceutical Sciences. 2025; 15(1):57-0. doi: 10.52711/2231-5659.2025.00008
Cite(Electronic):
Sreelakshmi K.P., Aleeda K.A., Febina K.S., Hiba mumthas K.P., Shahana Sherin K.T., Staicy Sebastian. Review on Gmelina arborea Roxb (Lamiaceae). Asian Journal of Research in Pharmaceutical Sciences. 2025; 15(1):57-0. doi: 10.52711/2231-5659.2025.00008 Available on: https://ajpsonline.com/AbstractView.aspx?PID=2025-15-1-8
REFERENCES:
1. Ved D K and Goraya G S. Demand and supply of medicinal plants in India. Bishen Singh Mahendra Pal Singh, Publishers and Distributors of Scientific Books, Dehradoon, 2008.
2. Navreet K, Sarabjit K, Bedi P M S, Ravinder, K. Preliminary Pharmacognostic study of Gmelina arborea bark. National Conference on Drug Innovation: Emerging Trends and Challenges, Kapurthala, India. 2012
3. Pattanayak P, Parhi P K, Mishra S K, Khandei P K. Screening of anti-Diabetic Activity of Bark Extracts of Gmelina aborea in Streptozotacin induced Diabetic Rats. International Journal of Pharmaceutical Sciences Review and Research. 2011; 8(2): 130-132.
4. Pravat K P, Priyabrata P, Paresh M, Manoj K P. An in-vivo study on analgesic and antipyretic activity of bark extract of Gmelina arborea. International Journal of Pharmaceutical Sciences Review and Research. 2011; 10(2): 78-81.
5. Vijay T, Dhana M S, Sarumathy K. Cardioprotective, antioxidant activities and phytochemical analysis by GC-MS of Gmelina arborea (GA) in Doxorubicin induced myocardial necrosis in Albino rats. Journal of Applied Phamaceutical Science. 2011; 1(05): 198-204.
6. Anonymous. The Ayurvedic Pharmacopoeia of India (Formulations).Part Ⅰ. New Delhi: Department of Indian Systems of Medicine and Homeopathy. 2003.13.
7. Kritikar K R, Basu B D. An I.C.S. Indian Medicinal Plants. International Book Distributors, Dehradun, 1987, 1931-1934.
8. K M Nadkarni Indian Plants and Drugs, Gmelina arborea, Ajay Book Service, New Delhi, First Edition 2010, p-152.
9. Ravindra Sharma. Agro-techniques of selected Medicinal plants, Department of Ayush, Chandalok Building 36, Janpath New Delhi.
10. Priya Vrat Sharma, Namarupajnanam, Varanasi, Chaukhambha Visvabharati, 2011, p-71.
11. Nadkarni AK, Indian Materia Medica. 3d ed. Bombay: Popular Prakasan; 1976.
12. Sharma PC, Yelna MB, Dennis TJ. Database on medicinal plants used in Ayurveda. Central Council for Research inn Ayurveda and siddha. Vol.3. Government of India. 2001
13. Kawamura F and Ohara S. Antifungal activity of iridoid glycosides from the heartwood of Gmelina arborea. Holzforschung. 2005; 59:153-155.
14. Nayak BS, Ellaiah P, Dinda SC. Antibacterial, antioxidant and antidiabetic activities of G. arborea fruit extracts Int J Green Pharm. 2012; 6: 224-30
15. Kaswala Rohith, Patel Vaibhav, Chakraborty Manodeep, Kamath Jagadish V. Phytochemical and pharmacological profile of Gmelina arborea; An overview, International Research Journal of Pharmacy. 2012; 3(2): 61-64.
16. Mahmood AM, Doughari JH and Kisman HS. In vitro antimicrobial activity of crude leaf and stem bark extracts of Gmelina arborea against some pathogenic species of Enterobacteriaceae. African J Pharm and Pharmacol. 2010; 4(6): 355-361.
17. Pravat K P, Priyabrata P, Paresh M, Manoj K P. An in-vivo study on analgesic and antipyretic activity of bark extract of Gmelina arborea. International Journal of Pharmaceutical Sciences Review and Research. 2011; 10(2): 78-81.