Author(s): Ghorpade Arti Changdev, S. S. Siddheshwar

Email(s): artighorpade2018@gmail.com

DOI: 10.52711/2231-5659.2024.00009   

Address: Ghorpade Arti Changdev*, S. S. Siddheshwar
Pravara Rural College of Pharmacy, Pravaranagar.
*Corresponding Author

Published In:   Volume - 14,      Issue - 1,     Year - 2024


ABSTRACT:
For medications with an absorption window in the stomach and upper part of small intestine, a controlled drug delivery system with a longer stomach residence duration can be particularly useful. Rapid gastrointestinal transit may cause drug delivery system above the absorption zone to only partially release drug, which would reduce the supplied dose's effectiveness. The main drawbacks are linked to the non-uniformity of drug absorption across the alimentary canal and the inter- and intra-subject variability of gastro-intestinal transit time. The bioavailability of medications is predicted to be improved by floating delivery systems, which are designed to stay buoyant on the gastric contents for an extended period of time. Floating in combination with swellable system gaining attention due to their wide applicability in the targeting of drugs to stomach. These floating and swellable tablet have the advantage that they remain buoyant and swells to 2-3 folds in gastric fluid.


Cite this article:
Ghorpade Arti Changdev, S. S. Siddheshwar. Gastroretentive Drug Delivery Systems with improved Floating and Swelling Capabilities. Asian Journal of Research in Pharmaceutical Sciences. Sci. 2024; 14(1):56-2 doi: 10.52711/2231-5659.2024.00009

Cite(Electronic):
Ghorpade Arti Changdev, S. S. Siddheshwar. Gastroretentive Drug Delivery Systems with improved Floating and Swelling Capabilities. Asian Journal of Research in Pharmaceutical Sciences. Sci. 2024; 14(1):56-2 doi: 10.52711/2231-5659.2024.00009   Available on: https://ajpsonline.com/AbstractView.aspx?PID=2024-14-1-9


REFERENCE:
1.    Sunil K. Jain, Govind P. Agrawal and Narendra K. Jain. Floating Microspheres as Drug Delivery System: Newer Approaches, Current Drug Delivery. 2008; 5: 220-223.
2.    Ying-Chen Chena, Hsiu-O Hoa, Tzu-Yu Leea, Ming-Thau Sheu. Physical characterizations and sustained release profiling of gastroretentive drug delivery systems with improved floating and swelling capabilities. Int. J. Pharm. 2013; 441: 162–169.
3.    Anupama Sarawade, M. P. Ratnaparkhi, Shilpa Chaudhari. An Overview Floating Drug Delivery System, International Journal of Research and Development in Pharmacy and Life Sciences. 2014; 5: 1106-1115.
4.    C Narendra, M S Srinath, Ganesh Babu. Optimization of bilayer floating tablets containing metoprolol tartrate as a model drug for gastric retention. AAPS PharmSciTech. 2006; 7(2): 34.
5.    Chanchal, Saurav Kumar, Satinder Kakar, 2018. A review on floating tablet. Indian Journal of Pharmaceutical and Biological Research(IJPBR)6(1):22-29.
6.    Eytan A. Klausner, Eran Lavy, Michael Friedman, Amnon Hoffman. Review E xpandable gastroretentive dosage forms, Journal of Controlled Release. 2003; 90: 143–162
7.    Shah SH, Patel JK, Patel NV. Stomach specific floating drug delivery system: A review. Int J Pharm Res. 2009; 1(3): 623-633.
8.    Satinder Kakar, Ramandeep Singh, Shallu Sandhan. Gastroretentive drug delivery system: A Review. AJPP. 2012; 5(3): 12 15.
9.    Solakhia TM, Kosta AK, Agarwal S, Gupta D. Bi-Layer Tablets: An Emerging Trend. International Journal of Pharmaceutical & Biological Archives. 2012; 3: 499- 506.
10.    Sowmya C, Suryaprakash CR, Tabasum SG, Varma V. An Overview on Bi-Layer Tablets. International Journal of Pharmacy and Technology. 2012; 4: 2143-2156.
11.    Meenu Bhatt, Satinder Kakar, Ramandeep Singh. A Review On Floating Drug Delivery System. IJRAPR. 2015; 5(2): 57-67
12.    Hong-Liang Lin, Ling-Chun Chen, Wen-Ting Cheng, Wei-Jie Cheng. Hsiu-O Ho, and Ming-Thau Sheu. Preparation and Characterization of a Novel Swellable and Floating Gastroretentive Drug Delivery System (sfGRDDS) for Enhanced Oral Bioavailability of Nilotinib. Pharmaceutics. 2020; 137: 8-13.
13.    Arza, R. A. K., Gonugunta, C. S. R., Veerareddy, P. R. Formulation and evaluation of swellable and floating gastroretentive ciprofloxacin hydrochloride tablets. AAPS PharmSciTech. 2009; 10: 220–226.
14.    Chen, R. N., Ho, H. O., Yu, C. Y., Sheu, M. T. Development of swelling/floating gastroretentive drug delivery system based on a combination of hydroxyethyl cellulose and sodium carboxymethyl cellulose for Losartan and its clinical relevance in healthy volunteers with CYP2C9 polymorphism. Eur. J. Pharm. Sci. 2010; 39: 82–89.
15.    V. Iannuccelli, G. Coppi, R. Sansone, G. Ferolla. Air compartment multiple-unit system for prolonged gastric residence. Part II. In vivo evaluation, Int. J. Pharm. 1998; 174; 55–62.
16.    I. R. Wilding, A. J. Coupe, S. S. Davis. The role of scintigraphy in oral drug delivery, Adv. Drug Deliv. Rev. 2001; 46; 103–124.
17.    G. N. J. Tytgat, in: T. Yamada (Ed.), Textbook of Gastroenterology. II, Vol. 2, J. B. Lippincott, Philadelphia. 1998; pp. 2544–2570.
18.    W. Weitschies, D. Cardini, M. Karaus, L. Trahms, W. Semmler. Magnetic marker monitoring of esophageal, gastric and duodenal transit of nondisintegrating capsules, Pharmazie. 1999; 54; 426–430.
19.    W. R. Hendee, in: C. E. Putman, C. E. Ravin (Eds.). Textbook of Diagnostic Imaging II, Vol. 1, W. B. Saunders, Philadelphia. 1994; pp. 1–6.
20.    S Sharma, P Atmaram. Low-density multiparticulate system for pulsatile release of meloxicam. Int J Pharm. 2006; 313:150-158.
21.    Tripathi P, Ubaidulla U, Khar RK, Vishwavibhuti. Floating Drug Delivery System. International Journal of Research and Development in Pharmacy and Life Sciences. 2012; 1: 1-10.
22.    Vishal Bhardwaj, Nirmala, S. L. Harikumar. A Review On Floating Drug Delivery System. Pharmacophore. International Research Journal. 2013; 4(1):26-38.
23.    Satinder Kakar, Ramandeep Singh, Alok Semwal. Drug release characteristics of dosage forms: a review. Journal of Coastal Life Medicine. 2014; 2(4): 332-336.

Recomonded Articles:

Author(s): Mohd. Yaqub Khan, Maryada Roy, Brijesh Kumar Saroj, Sudhakar Dubey, Vineet Kumar Sharma

DOI: 10.5958/2231-5659.2015.00019.3         Access: Open Access Read More

Author(s): Priyanka M. Salve, Shital V. Sonawane, Mayuri B. Patil, Rajendra K. Surawase

DOI: 10.52711/2231-5659.2021.00037         Access: Open Access Read More

Author(s): Vishal Kumar, Attish Bhardwaj, Navdeep Singh, Kamya Goyal, Shammy Jindal

DOI: 10.52711/2231-5659.2021.00038         Access: Open Access Read More

Author(s): Saudagar R. B., Sarika V. Khandbahale

DOI: 10.5958/2231-5659.2017.00005.4         Access: Open Access Read More

Author(s): K.Vijaya Sri, Guda Santhoshini, D. Ravi Sankar, K.Niharika

DOI: 10.5958/2231-5659.2018.00005.X         Access: Open Access Read More

Author(s): Girishchandra R. Mandake, Indrajit S. Patil, Omkar A Patil, Manoj M. Nitalikar, Shriniwas K Mohite

DOI: 10.5958/2231-5659.2018.00012.7         Access: Open Access Read More

Author(s): Aprajita Shifali, Pravin Kumar, Vinay Pandit

DOI: 10.5958/2231-5659.2021.00012.6         Access: Open Access Read More

Author(s): Ch. Nagadev, M. Durga Srinivasa Rao, P. Venkatesh, D. Hepcykalarani, R. Prema

DOI: 10.5958/2231-5659.2020.00021.1         Access: Open Access Read More

Author(s): Surekha Baghel, Bina Gidwani, Chanchal Deep Kaur

DOI: 10.5958/2231-5659.2017.00009.1         Access: Open Access Read More

Author(s): D.M. Shinkar, Bhushan S Bhamare, R.B. Saudagar

DOI: 10.5958/2231-5659.2016.00011.4         Access: Open Access Read More

Author(s): Nikunja B. Pati, T. Swayam Jyothi, Gajender Singh Thakur, Sushma Reddy, G. Meghna

DOI: 10.5958/2231-5659.2017.00028.5         Access: Open Access Read More

Author(s): Saurabh Tiwari, Shweta Singh, Pushpendra Kumar Tripathi, Chetan Kumar Dubey

DOI: 10.5958/2231-5659.2015.00037.5         Access: Open Access Read More

Author(s): Deepak Prashar, Dharmesh Sharma

DOI:         Access: Open Access Read More

Author(s): D.M. Shinkar, Aarif S. Khatik, R.B. Saudagar

DOI: 10.5958/2231-5659.2016.00022.9         Access: Open Access Read More

Author(s): Smita Kolhe, Praveen Chaudhari, Dhananjay More

DOI:         Access: Open Access Read More

Author(s): Divya B., Sabitha P., Ravindra Reddy, M. Kranthi Kumar Reddy , B.Narasimha Rao

DOI:         Access: Open Access Read More

Author(s): Sudhir Sawant, Ramesh Yamgar

DOI:         Access: Open Access Read More

Author(s): Sarika S. Lokhande

DOI: 10.5958/2231-5659.2019.00032.8         Access: Open Access Read More

Asian Journal of Research in Pharmaceutical Sciences (AJPSci) is an international, peer-reviewed journal, devoted to pharmaceutical sciences....... Read more >>>

RNI: Not Available                     
DOI: 10.52711/2231-5659 


Recent Articles




Tags