Author(s): Tanmay Jit, Dibyendu Shil, Ramesh Kumari Dasgupta, Sanglap Mallick, Saptarshi Mukherjee

Email(s): tanmayjit2016@gmail.com

DOI: 10.52711/2231-5659.2023.00050   

Address: Tanmay Jit1*, Dibyendu Shil2, Ramesh Kumari Dasgupta3, Sanglap Mallick1, Saptarshi Mukherjee4
1Department of Pharmaceutics, Mata Gujri College of Pharmacy, Mata Gujari University, Kishanganj, Bihar, 855107, India.
2Department of Pharmacognosy, Mata Gujri College of Pharmacy, Mata Gujari University, Kishanganj, Bihar, 855107, India.
3Department of Pharmaceutical Chemistry, Mata Gujri College of Pharmacy, Mata Gujari University, Kishanganj, Bihar, 855107, India.
4Department of Pharmaceutical Technology, University of North Bengal, Raja Ramohanpur, Darjeeling-734013, India.
*Corresponding Author

Published In:   Volume - 13,      Issue - 4,     Year - 2023


ABSTRACT:
The majority of the active pharmaceutical components have issues with poor solubility, bioavailability, chemical stability, and moisture absorption. Pharmaceutical crystals are a reliable way to change the aforementioned physicochemical properties of drugs without changing their pharmacological behaviour. However, the success of these approaches depends on the physical and chemical properties of the molecules being developed. The development of drug products with superior physicochemical characteristics, such as melting point, tablet ability, solubility, stability, bioavailability, and permeability, while preserving the pharmacological properties of the active pharmaceutical ingredient is greatly facilitated by co-crystallization of drug substances. All the components of a cocrystal, which is a stoichiometric homogeneous multicomponent system connected by non-covalent interactions, are solid under ambient conditions.


Cite this article:
Tanmay Jit, Dibyendu Shil, Ramesh Kumari Dasgupta, Sanglap Mallick, Saptarshi Mukherjee. Cocrystal: A Review on the Design and Preparation of Pharmaceutical Cocrystals. Asian Journal of Research in Pharmaceutical Sciences. 2023; 13(4):296-2. doi: 10.52711/2231-5659.2023.00050

Cite(Electronic):
Tanmay Jit, Dibyendu Shil, Ramesh Kumari Dasgupta, Sanglap Mallick, Saptarshi Mukherjee. Cocrystal: A Review on the Design and Preparation of Pharmaceutical Cocrystals. Asian Journal of Research in Pharmaceutical Sciences. 2023; 13(4):296-2. doi: 10.52711/2231-5659.2023.00050   Available on: https://ajpsonline.com/AbstractView.aspx?PID=2023-13-4-5


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