Author(s): Vidya Ashok Kheradkar, Jameel Ahmed S. Mulla

Email(s): jameelahmed5@rediffmail.com

DOI: 10.52711/2231-5659.2023.00020   

Address: Vidya Ashok Kheradkar, Jameel Ahmed S. Mulla*
Department of Pharmaceutics, Shree Santkrupa College of Pharmacy, Ghogaon, Karad, MS-415111, India.
*Corresponding Author

Published In:   Volume - 13,      Issue - 2,     Year - 2023


ABSTRACT:
Nanotechnology includes nanosuspensions. Nanotechnology has become a huge area in the world of medicine. An appealing and promising approach to address the lipophilic like bio-available and poor solvability concerning the pharmaceuticals is nanosuspension. The majority of recently developed medications have poor water solubility. Drug formulation is usually complicated by medicines' limited water solubility. There are numerous standard methods for improving the solubility of pharmaceuticals that are poorly soluble, including Media Milling, Homogenization, precipitation technique, et cetera. A new approach in medication development is the development disintegrable medicinal formulations using nanotechnology. Particle sizes used in nanotechnology range are from 1 to 1000 nm. The increase in dissolving rate that results from drug particle size reduction into the submicron region naturally improves bioavailability. An efficient new method for improving the dissolution of low soluble in water medicines is nanosuspension technology. A nanosuspension improves the safety and effectiveness of a medicine by addressing issues with lipophilic like bio-available and poor solvability, as well as by changing the pharmacokinetics.


Cite this article:
Vidya Ashok Kheradkar, Jameel Ahmed S. Mulla. Nanosuspension: A Novel Technology for Drug Delivery. Asian Journal of Research in Pharmaceutical Sciences. 2023; 13(2):106-0. doi: 10.52711/2231-5659.2023.00020

Cite(Electronic):
Vidya Ashok Kheradkar, Jameel Ahmed S. Mulla. Nanosuspension: A Novel Technology for Drug Delivery. Asian Journal of Research in Pharmaceutical Sciences. 2023; 13(2):106-0. doi: 10.52711/2231-5659.2023.00020   Available on: https://ajpsonline.com/AbstractView.aspx?PID=2023-13-2-6


REFERENCES:
1.    Goel S, Sachdeva M, Agarwal V. Nanosuspension technology: recent patents on drug delivery and their characterizations. Recent patents on drug delivery & formulation. 2019 Jun 1;13(2):91-104.
2.    Arora D, Khurana B, Rath G, Nanda S, Goyal AK. Recent advances in nanosuspension technology for drug delivery. Current Pharmaceutical Design. 2018 Jun 1;24(21):2403-15.
3.    Shah DP, Patel B, Shah C. Nanosuspension technology: A innovative slant for drug delivery system and permeability enhancer for poorly water soluble drugs. Journal of Drug Delivery and Therapeutics. 2015 Jan 13;5(1):10-23.
4.    Khandbahale SV. A review-Nanosuspension technology in drug delivery system. Asian Journal of Pharmaceutical Research. 2019;9(2):130-8.
5.    Kumar Singh S, Vaidya Y, Gulati M, Bhattacharya S, Garg V, Kumar Pandey N. Nanosuspension: principles, perspectives and practices. Current drug delivery. 2016 Dec 1;13(8):1222-46.
6.    Afifi SA, Hassan MA, Abdelhameed AS, Elkhodairy KA. Nanosuspension: an emerging trend for bioavailability enhancement of etodolac. International journal of polymer science. 2015 Jan 1;2015.
7.    Aher SS, Malsane ST, Saudagar RB. Nanosuspension: an overview. Int J Curr Pharm Res. 2017 Jun 28;9(3):19-23.
8.    Patel HM, Patel BB, Shah CN. Nanosuspension: a novel approach to enhance solubility of poorly water soluble drugs-a review. Int J Adv Pharm. 2016;5(2):21-9.
9.    Vedaga SB, Gondkar SB,. Saudagar R.B Nanosuspension: An emerging trend to improve solubility of poorly water soluble drugs. Journal of Drug Delivery & Therapeutics. 2019; 9(3):549-553.
10.    Rinku Jayaprakash, K. Krishnakumar, B. Dineshkumar, Rejin Jose, Smitha K Nair Nanosuspension in Drug Delivery-A Review Scholars Academic Journal of Pharmacy (SAJP) 2016; 5(5): 138-141.
11.    Chen A, Shi Y, Yan Z, Hao H, Zhang Y, Zhong J, Hou H. Dosage form developments of nanosuspension drug delivery system for oral administration route. Current pharmaceutical design. 2015 Sep 1;21(29):4355-65.
12.    Yadollahi R, Vasilev K, Simovic S. Nanosuspension technologies for delivery of poorly soluble drugs. Journal of Nanomaterials. 2015 Jun 1;2015.
13.    Mathew M, Krishnakumar K, Dineshkumar B, Nair SK. Antibiotics nanosuspension: A review. Journal of Drug Delivery and Therapeutics. 2017 Mar 15;7(2):128-31.
14.    Sahu BP, Hazarika H, Bharadwaj R, Loying P, Baishya R, Dash S, Das MK. Curcumin-docetaxel co-loaded nanosuspension for enhanced anti-breast cancer activity. Expert opinion on drug delivery. 2016 Aug 2;13(8):1065-74.
15.    Wang L, Du J, Zhou Y, Wang Y. Safety of nanosuspensions in drug delivery. Nanomedicine: Nanotechnology, Biology and Medicine. 2017 Feb 1;13(2):455-69.
16.    I Jethara S, D Patel A, R Patel M, S Patel M, R Patel K. Recent survey on nanosuspension: a patent overview. Recent Patents on Drug Delivery & Formulation. 2015 Apr 1;9(1):65-78.
17.    Kulkarni RR, Phadtare DG, Saudagar RB. A novel approach towards nanosuspension. Asian Journal of Pharmaceutical Research. 2015;5(4):186-94.
18.    Parekh KK, Paun JS, Soniwala MM. Formulation and evaluation of nanosuspension to improve solubility and dissolution of diacerein. International Journal of Pharmaceutical Sciences and Research. 2017 Apr 1;8(4):1643.
19.    Vadje SS, Surwase RK, Shinde ME, Patil KR, Pagare SB. Nanosuspension: A Novel Technology for the Drug Delivery System.
20.    Du J, Li X, Zhao H, Zhou Y, Wang L, Tian S, Wang Y. Nanosuspensions of poorly water-soluble drugs prepared by bottom-up technologies. International journal of pharmaceutics. 2015 Nov 30;495(2):738-49.
21.    Azimullah S, Sudhakar CK, Kumar P, Patil A, Usman MR, Usman MZ, Jain BV. Nanosuspensions as a promising approach to enhance bioavailability of poorly soluble drugs: An update. Journal of Drug Delivery and Therapeutics. 2019 Mar 20;9(2):574-82.
22.    Rajashri R. Kulkarni, Dipti G. Phadtare, Ravindra B. Saudagar. A Novel Approach Towards Nanosuspension. Asian J. Pharm. Res. 5(4): 2015;186-194.
23.    Sarika V. Khandbahale. A Review- Nanosuspension Technology in Drug Delivery System. Asian J. Pharm. Res. 2019; 9(2): 130-138.
24.    Smita S. Aher, Sagar T. Malsane, R. B. Saudagar. Nanosuspension: An Overview. Asian J. Res. Pharm. Sci. 2017; 7(2):81-86.
25.    Pawar Pravin, Yadav Adhikrao, Gharge Varsha. Different Techniques for Preparation of Nanosuspension with Reference to its Characterisation and various Applications - A Review. Asian J. Res. Pharm. Sci. 2018; 8(4): 210-216.
26.    Paun J.S., Tank H.M. Nanosuspension: An Emerging Trend for Bioavailability Enhancement of Poorly Soluble Drugs. Asian J. Pharm. Tech. 2(4): Oct. - Dec. 2012; Page 157-168.
27.    Ashok. P, Meyyanathan. S. N, R. Vadivelan, Jawahar. N. Nanosuspensions by Solid Lipid Nanoparticles method for the Formulation and in vitro/in vivo characterization of Nifedipine. Asian J. Res. Pharm. Sci. 2021; 11(1):1-6.
28.    Atul Phatak, Pallavi Jorwekar, P.D. Chaudhari. Nanosuspensions: A Promising Nanocarrier Drug Delivery System. Research J. Pharma. Dosage Forms and Tech. 2011; 3(5): 176-182 .
29.    Phatak Atul A., Chaudhari Praveen D. Development and Evaluation of Nanogel as a Carrier for Transdermal Delivery of Aceclofenac. Asian J. Pharm. Tech. 2(4): Oct. - Dec. 2012; Page 125-132.
30.    S. D. Mankar, Anjali Dama, M. S. Bhosale, Dr. S. S. Sidhheshwar. Design, Development, Characterization of Solid Lipid Nanoparticles for Oral Administration. Research J. Science and Tech. 2020; 12(1):79-95.
31.    Prashant S. Wake, M. D. Kshirsagar. Design and Characterization of Solid Lipid Nanoparticle Based Transdermal Drug Delivery System. Asian J. Res. Pharm. Sci. 2017; 7(2): 87-91.
32.    Dudhwala Y, Dedania R, Ramani V. Nanosuspension: Novel Approach for Drug Delivery. Journal of Integrated Pharmaceutical Sciences. 2021;1(1):37-58.
33.    Saddam H, Abdul Baquee A, Jiban D. Nanosuspension: a promising drug delivery system for poorly water soluble drug and enhanced bioavailability. Int J Pharm Sci and Res. 2020;10(11):4822-32.
34.    Jassim ZE, Rajab NA. Review on preparation, characterization, and pharmaceutical application of nanosuspension as an approach of solubility and dissolution enhancement. J Pharm Res. 2018;12:771-4.
35.    Geetha G, Poojitha U, Khan KA. Various techniques for preparation of nanosuspension-A Review. International Journal of Pharma Research & Review. 2014 Sep;3(9):30-7.

Recomonded Articles:

Author(s): Mohd. Yaqub Khan, Maryada Roy, Brijesh Kumar Saroj, Sudhakar Dubey, Vineet Kumar Sharma

DOI: 10.5958/2231-5659.2015.00019.3         Access: Open Access Read More

Author(s): Sarika V. Khandbahale, Kanchan R. Pagar, Rupali. V. Khankari

DOI: 10.5958/2231-5659.2019.00018.3         Access: Open Access Read More

Author(s): Priyanka M. Salve, Shital V. Sonawane, Mayuri B. Patil, Rajendra K. Surawase

DOI: 10.52711/2231-5659.2021.00037         Access: Open Access Read More

Author(s): Mohd. Yaqub Khan, Maryada Roy, Imtiyaz Ahmad, Irfan Aziz, Manju Panday

DOI: 10.5958/2231-5659.2015.00024.7         Access: Open Access Read More

Author(s): Vishal Kumar, Attish Bhardwaj, Navdeep Singh, Kamya Goyal, Shammy Jindal

DOI: 10.52711/2231-5659.2021.00038         Access: Open Access Read More

Author(s): Dibyajyoti Saha, Milan Hait, Mayukh Jana, Suprodip Mandal, Utpal Jana

DOI:         Access: Open Access Read More

Author(s): Saudagar R. B., Sarika V. Khandbahale

DOI: 10.5958/2231-5659.2017.00005.4         Access: Open Access Read More

Author(s): K.Vijaya Sri, Guda Santhoshini, D. Ravi Sankar, K.Niharika

DOI: 10.5958/2231-5659.2018.00005.X         Access: Open Access Read More

Author(s): Pradnya M. Khandagale, Bhushan Bhairav, R. B. Saudagar

DOI: 10.5958/2231-5659.2016.00038.2         Access: Open Access Read More

Author(s): Aprajita Shifali, Pravin Kumar, Vinay Pandit

DOI: 10.5958/2231-5659.2021.00012.6         Access: Open Access Read More

Author(s): Rajashri R. Kulkarni, Dipti G. Phadtare, Ravindra B. Saudagar

DOI: 10.5958/2231-5659.2016.00019.9         Access: Open Access Read More

Author(s): Sable Kundan Dattatraya, Sable Kiran Dattatray, Kathwate Ganesh Sunil, Mane Snehal Suryakant

DOI: 10.5958/2231-5659.2020.00027.2         Access: Open Access Read More

Author(s): Girishchandra R. Mandake, Indrajit S. Patil, Omkar A Patil, Manoj M. Nitalikar, Shriniwas K Mohite

DOI: 10.5958/2231-5659.2018.00012.7         Access: Open Access Read More

Author(s): Vrushali R. Kadam, M. P. Patil, Vrushali V. Pawar, Sanjay Kshirsagar

DOI: 10.5958/2231-5659.2017.00030.3         Access: Open Access Read More

Author(s): Ismail Hussain, Ravikumar, Narayanaswamy VB, Injamamul Haque, Mohibul Hoque

DOI: 10.5958/2231-5659.2016.00030.8         Access: Open Access Read More

Author(s): S. S. Shuka, Bina Gidwani, R. Pandey, S. P. Rao, V. Singh, Amber Vyas

DOI:         Access: Open Access Read More

Author(s): Pradeep Sahu, Neha Pinkalwar, Ravindra Dhar Dubey, Shweta Paroha, Shilpi Chatterjee, Tanushree Chatterjee

DOI:         Access: Open Access Read More

Author(s): Ch. Nagadev, M. Durga Srinivasa Rao, P. Venkatesh, D. Hepcykalarani, R. Prema

DOI: 10.5958/2231-5659.2020.00021.1         Access: Open Access Read More

Author(s): Viral Patel

DOI:         Access: Open Access Read More

Author(s): Surekha Baghel, Bina Gidwani, Chanchal Deep Kaur

DOI: 10.5958/2231-5659.2017.00009.1         Access: Open Access Read More

Asian Journal of Research in Pharmaceutical Sciences (AJPSci) is an international, peer-reviewed journal, devoted to pharmaceutical sciences....... Read more >>>

RNI: Not Available                     
DOI: 10.52711/2231-5659 


Recent Articles




Tags