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Asian Journal of Research in Pharmaceutical Sciences
ISSN: 2231-5659(Online), 2231-5640(Print)
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Importance and Utility of Vagina as a Route for Drug Delivery System
Tapan Kishor Nayak
Amit Roy, Ananta Choudhury*, Tapan Kishor Nayak
Columbia Institute of Pharmacy, Tekari, Raipur (493111)
The purpose of this review article is to highlight the importance of vaginal drug delivery system. Several studies proven that vagina is an effective route for drug administration intended for local action as well as systemic action. This route offers many advantages due to its large permeation area, permeability to large molecular weight drugs, rich vascularization, avoidance of first pass metabolism and relatively low enzymatic activity. Through this route steroidal compounds, spermicidal agents are already delivered to obtain suitable therapeutics action for prolong period of time with minimal side effects. Recently the vaginal route has been investigated for peptide and protein drug delivery. In this review we focused on different aspects related to vaginal drug delivery systems along with their anatomy physiology and factors affecting drug absorption from the vaginal route.
Vagina, Intravaginal route, peptide and protein drug delivery.
Amit Roy, Ananta Choudhury, Tapan Kishor Nayak. Importance and Utility of Vagina as a Route for Drug Delivery System. Asian J. Res. Pharm. Sci. 4(2): April-June 2014; Page 86-92.
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