Author(s): Sangar Omkar S., Patil Aishwarya C., Payghan Santosh A.

Email(s): omkarsangar100@gmail.com

DOI: 10.52711/2231-5659.2022.00003   

Address: Sangar Omkar S.*, Patil Aishwarya C., Payghan Santosh A.
Department of Pharmaceutics, Vasantidevi Patil Institute of Pharmacy, Kodoli, Tal- Panhala, Dist – Kolhapur (MH)
*Corresponding Author

Published In:   Volume - 12,      Issue - 1,     Year - 2022


ABSTRACT:
Nanoparticles can offer important advantages over the administration of conventional drugs in terms of high stability, high specificity, high drug transport capacity, controlled release capacity, possibility of use in different routes of administration and the ability to administer drugs both hydrophilic and hydrophobic molecules. Nanoparticles are being used for various purposes, from medical treatments, use in various branches of the production industry such as solar and for energy storage, to a wide incorporation obsessed with various everyday materials such as cosmetics or dress, optical devices, catalytic, bactericidal, electronics, sensor technology, biological labelling and treatment of some cancers. Nanoparticles can be chemically or biologically synthesized. This review focuses on the need to develop nanoparticles, advantages, disadvantages, synthesis, properties, applications of nanoparticles exist in different forms. Nanoparticles are very capable in selective tumour contact cancer therapy due to their small size and modifiability. These particles consist of pure active pharmaceutical ingredients and are stabilized regularly with surfactant. Nanoparticles are tiny materials that have particle sizes in the range of 1 to 1000 nm.


Cite this article:
Sangar Omkar S., Patil Aishwarya C., Payghan Santosh A.. Nanoparticles: As a Nano based Drug Delivery System. Asian Journal of Research in Pharmaceutical Sciences. 2022; 12(1):11-6. doi: 10.52711/2231-5659.2022.00003

Cite(Electronic):
Sangar Omkar S., Patil Aishwarya C., Payghan Santosh A.. Nanoparticles: As a Nano based Drug Delivery System. Asian Journal of Research in Pharmaceutical Sciences. 2022; 12(1):11-6. doi: 10.52711/2231-5659.2022.00003   Available on: https://ajpsonline.com/AbstractView.aspx?PID=2022-12-1-3


REFERENCE:
1.    Santosh J Pawar, Pruthviraj S Pawar, Sachin B Jadhav, Alkunte AS, Patil SM. Nanocapsules as a Novel Drug Delivery System. Research J. Pharma. Dosage Forms and Tech. 2010; 2(2):146-155.
2.    De Berardis B, Civitelli G, Condello M, Lista P, Pozzi R, Arancia G, Meschini, S. Exposure of ZnO nanoparticles causes oxidative stress and cytotoxicity in human colon carcinoma cells. 2010; 246 (3): 116-127. published by google
3.    Sarika V. Khandbahale, R. B. Saudagar. Nanoparticle- A Review. Asian J. Res. Pharm. Sci. 2017; 7(3):162-172.
4.    J. Madhusudhanan, M. Indumathi, S. Ammu. A Novel System for Drug Delivery Using Nanoparticle. Asian J. Pharm. Tech. 2013; Vol. 3: Issue 4, Pg 137-141.
5.    Lewinski N, Colvin V, Drezek R. Cytotoxicity of nanoparticles. a little. 2008;4(1):26–49. Published by Google
6.    Langer R. Biomaterials in drug delivery and tissue building one laboratory experience. Acc Chem Res 2000; 33: 94-101.
7.    National nanotechnology system. Available at http://www.nano.gov/Html/facts/EHS.htm (accessed 2004).
8.    Masciangioli, T.; Zhang, W. X. Environmental Technologies at the Nanoscale; Environ. Sci. Technol. 2003, 37, 102a-108a.
9.    Colvin, V. Point of Impact: Where Technology Collides with Society, Business, and Personal Lives; Technol. Rev. 2003, 106, 71-73.
10.    Vila A., Tobio M., Alonso MJ. Design of biodegradable particles for protein delivery. Journal of Control Release. 2002: 78:15-24.
11.    A novel controlled release formulation for the anticancer drug paclitaxel, PLGA nanoparticles containing vitamin-E TPGS.  Journal of Control Release. 2003; 86:33-48.
12.    Sapra P., Tyagi P., Allen TM. Ligand targeted liposomes in cancer treatment. Current Drug Delivery. 2005; 2:369-381.
13.    Gaur A., Mindha A., Bhatiya AL. Nanotechnology in Medical Sciences. Asian Journal of Pharmaceutics. 2008; 80-85.
14.    Mohanraj VJ., Chen Y. Nanoparticles a review. Tropical Journal of Pharmaceutical Research. 2006; 5: 561-573.
15.    Hett A. Nanotechnology: small matters, many unknown. Swiss Re, risk Perception Series, Zurich 2004.
16.    Kolher M., Nanotechnology, An introduction of nano-structuring. Wiley-VCH. 2007; 2.  
17.    Dendrimers as quantised building blocks for nanoscale synthetic Organic Chemistry. 2004; 37:39-57.
18.    Abhijit Ray. Fullerence (C60) Molecule – A Review. Asian J. Pharm. Res. 2(2): April-June 2012; Page 47-50.
19.    Wiener EC., Brothers H., Gansow OA. Dendrimers- based metal chelates. Magnetic Resonance in Medicine. 1994; 31:1-8.
20.    Li Y., Cheng Y. design, synthesis and potent pharmaceutical application of glycodendrimers: a mini review. Current Drug Discovery Technology. 2007; 4: 246-254.
21.    Cheng Y., Wang J., Rao T. Pharmaceutical application of dendrimers: promising nanocarriers for drug delivery. 2008; 13: 1447-1471.
22.    Mecke A., Ramamurthy A., Baker JR. Direct observation of lipid bilayer disruption by poly dendrimers. Chemistry and Physics of Lipids. 2004; 132:3-14.
23.    Larson DR., Williams RM., Clark SW., Wise FW. Water soluble quantum dots for multiphoton florescence imaging in vivo. Science. 2003; 300:1434-1436.
24.    Indranil Singh. A Review on in-Vivo Imaging of Cancer Cells by Bioconjugated Quantum Dots. Asian J. Pharm. Res. 2018; 8(4): 243-248
25.    Kreuter J. nanoparticles in colloidal drug delivery system, J, K, Ed. Marcel Dekker New York. 1994; 219-342.
26.    Redhead HM., Devis SS. Drug delivery in poly nanoparticles surface modified with poloxamer 407 and poloxamine 908: Journal of Control Release. 2001; 70:353-363.
27.    Betancor, L., Bioinspired enzyme encapsulation for biocatalysis. Trends in Biotechnology. 2008; 26:566-572.
28.    Molpeceres J., Aberturas MR., Guzman M. Biodegradable nanoparticles as a delivery system for cyclosporine: preparation and characterization. J Microencapsul. 2000; 17: 599-614.
29.    DeAssis DN., Mosqueira VC., Vilela JM., Andrade M.S., Cardoso VN. Release profiles and morphological characterization by atomic force microscopy and photon correlation spectroscopy of 99m Technetium – fluconazole Nano Capsules. Int J Pharm. 2008; 349: 152 – 160.
30.    Muhlen AZ., Muhlen EZ., Mehnert W. atomic force microscopy studies of solid lipid nanoparticles. Pharmaceutical Research. 1996; 13:1411-1416.
31.    Polakovic M., Gorner T., Gref R., Dellacherie E. Lidocaine loaded biodegradable nanospheres. Modelling of drug release. Journal of Control Release. 1999; 60:169-177. http://dx.doi.org/10.1016/S0168- 3659(99)00012-7
32.    Scholes PD., Davis SS., Wats JF., Vert M., Davies MC. Detection and determination of surface level of poloxamer and PVA surfactant on biodegradable nanospheres. Journal of Control Release. 1999; 59:261-278.
33.    Alexis, F., Pridgen, E., Molnar, L.K., Farrokhzad, O.C., 2008.  Factors affecting the clearance and biodistribution of polymeric nanoparticles. Mol. Pharm. 5, 505–515.
34.    Margolis JA., Hoffman JM., Herfkens RJ., Jeffrey RB., Quon A., Gambhir SS. Molecular imaging techniques in body imaging.  Radiology. 2007; 2:245, 333-356. http://dx.doi.org/10.1148/ radiol.2452061117 PMid:17940297
35.    Weissleder R. Scaling down imaging: molecular mapping of cancer in mice. Nature Reviews Cancer. 2002; 2:11-18.
36.    Aabasaheb B. Tambve, Prakash D. Jadhav, Mayur N. Ghotkar, Ashwinkumar S. Chougule, Smita P. Borkar. A Review on Nanoparticles. Asian J. Pharm. Tech. 2020; 10(2):118-120.
37.    Pradeep Sahu, Swati Chaturvedi, Ravindra Dhar Dubey, Shweta Paroha, Shilpi Chatterjee, Tanushree Chatterjee. Nanoparticles- Drug Delivery System in Cancer Therapy. Research J. Pharma. Dosage Forms and Tech. 2011; 3(2): 33-41.
38.    Hiral A. Makadia, Ami Y. Bhatt, Ramesh B. Parmar, Ms. Jalpa S. Paun, H.M. Tank. Self-nano Emulsifying Drug Delivery System (SNEDDS): Future Aspects. Asian J. Pharm. Res. 3(1): Jan.-Mar. 2013; Page 20-26.


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