Author(s): Sanyam Sharma, Rahul Sharma, Kamya Goyal, Shammy Jindal


DOI: 10.5958/2231-5659.2021.00009.6   

Address: Sanyam Sharma1, Rahul Sharma1, Kamya Goyal2, Shammy Jindal2,3*
1Research Scholar, Laureate Institute of Pharmacy, Kathog, Jawalamukhi, Himachal Pradesh 176031, India.
2Associate Professor, Laureate Institute of Pharmacy, Kathog, Jawalamukhi, Himachal Pradesh 176031, India.
3 Research Scholar, Amity Institute of Pharmacy, Amity University, Uttar Pradesh, Sector-125, Noida 201303, India.
*Corresponding Author

Published In:   Volume - 11,      Issue - 1,     Year - 2021

Psoriasis is an inflammatory, auto immune disorder of the skin affecting 2 to 3% of people globally. It mainly affects all of the body parts especially hands, foot and limbs. In psoriasis, body starts to make new skin cells more rapidly than normal leads to the development of raised skin patches and tissues on the skin. Various kinds of treatment options are available for the treatment of psoriasis but they all are associated with various kinds of side effects. There is research gap between the use of various herbs and crude drugs used in the treatment of psoriasis with various dosage forms. Till now reviews are not available with treatment of psoriasis with herbal formulation. In this review, our objective is to cover the treatment options available for the treatment of psoriasis with the potential of herbs used for the psoriasis. In this review, we summarized a list of herbal plants which are known to have potential antipsoriatic activity and can be used for the treatment of psoriasis. But, most of the available literature of herbals are lacking clinical outcome of efficacy of herbals in treating the psoriasis. In the last, we can say that herbs from various natural origin can be used in the treatment of psoriasis as compared to synthetic drugs. This review will help or motivate the researcher for the evaluation of antipsoriatic potential of these herbs with all the safety features and help them to use this information for the development of herbal dosage forms that can effectively used for the management and treatment of psoriasis.

Cite this article:
Sanyam Sharma, Rahul Sharma, Kamya Goyal, Shammy Jindal. Potential of herbal treatment of Psoriasis: A Laconic Review. doi: 10.5958/2231-5659.2021.00009.6

1.      Po LW. Clinical measures of disease severity and outcome in psoriasis: a critical appraisal of their quality. British Journal of Dermatology. 1999 Aug;141(2):185-91. DOI: 10.1046/j.1365-2133.1999.02963x.

2.      Jindal S, Awasthi R, Singare D, Kulkarni GT. Potential Of Herbal Nanocarrier Formulation For The Treatment Of Psoriasis. International Journal of Pharmacy & Life Sciences. 2019 Jun 1;10(6).,+Awasthi+R,+Singare+D,+Kulkarni+GT.+Potential+Of+Herbal+Nanocarrier+Formulation+For+The+Treatment+Of+Psoriasis.+International+Journal+of+Pharmacy+%26+Life+Sciences.+2019+Jun+1%3B10(6).&hl=en&as_sdt=0,5

3.      Parisi R, Symmons DP, Griffiths CE, Ashcroft DM. Global epidemiology of psoriasis: a systematic review of incidence and prevalence. Journal of Investigative Dermatology. 2013, 1;133(2):377-85. https://

4.      Sanford JA, Gallo RL. Functions of the skin microbiota in health and disease. InSeminars in immunology 2013, 30 (Vol. 25, No. 5, pp. 370-377). Academic Press. j.smim.2013.09.005

5.      Capon F. The genetic basis of psoriasis. International Journal of Molecular Sciences. 2017;18(12):2526. ijms18122526

6.      Finlay AY, Khan G. Dermatology Life Quality Index (DLQI)—a simple practical measure for routine clinical use. Clinical and experimental dermatology. 1994;19(3):210-6.

7.      Jindal S, Awasthi R, Singhare D, Kulkarni GT. Topical delivery of Tacrolimus using liposome containing gel: An emerging and synergistic approach in management of psoriasis. Medical Hypotheses. 2020 May 15:109838. j.mehy.2020.109838

8.      Eghlileb AM, Davies EE, Finlay AY. Psoriasis has a major secondary impact on the lives of family members and partners. British Journal of Dermatology. 2007;156(6):1245-50.

9.      Schadler ED, Ortel B, Mehlis SL. Biologics for the primary care physician: review and treatment of psoriasis. Disease-a-Month. 2019; 1;65(3):51-90. 2018.06.001

10.   Rendon A, Schäkel K. Psoriasis pathogenesis and treatment. International journal of molecular sciences. 2019;20(6):1475.

11.   Avila R, Pugh DG, Slocumb CH, Winkelmann RK. Psoriatic arthritis: a roentgenologic study. Radiology. 1960;75(5):691-702.

12.   Nevitt GJ, Hutchinson PE. Psoriasis in the community: prevalence, severity and patients' beliefs and attitudes towards the disease. British Journal of Dermatology. 1996;135(4):533-7.

13.   Benhadou F, Mintoff D, Schnebert B, Thio HB. Psoriasis and microbiota: a systematic review. Diseases. 2018;6(2):47.

14.   Davidovici BB, Sattar N, Jörg PC, Puig L, Emery P, Barker JN, Van De Kerkhof P, Ståhle M, Nestle FO, Girolomoni G, Krueger JG. Psoriasis and systemic inflammatory diseases: potential mechanistic links between skin disease and co-morbid conditions. Journal of Investigative Dermatology. 2010;1;130(7):1785-96.

15.   Fortune DG, Richards HL, Kirby B, Bowcock S, Main CJ, Griffiths CE. A cognitive‐behavioural symptom management programme as an adjunct in psoriasis therapy. British Journal of Dermatology. 2002;146(3):458-65.

16.   Nirbhavane P, Sharma G, Verma S, Jadon RS, Singh B, Katare OP. Nail Psoriasis Treatment: Insights into Current Progress and Future Trends. Critical Reviews™ in Therapeutic Drug Carrier Systems. 2020;37(2). 10.1615/CritRevTherDrugCarrierSyst.2020029259

17.   Unissa R, Kumar PM, Pasha M, Begum S, Maheswari B. Psoriasis: A Comprehensive Review. Asian Journal of Research in Pharmaceutical Science. 2019;9(1):29-38.

18.   Badanthadka M, D’Souza L. Imiquimod-Induced Psoriasis Mice Model: A Promising Tool for Psoriasis Research?. Research Journal of Pharmacy and Technology. 2020 Jul 28;13(7):3508-15.

19.   Sumithra M, Majeed AM, Chitra V. Cell Lines and Animal Models of Psoriasis. Research Journal of Pharmacy and Technology. 2020;13(3):1601-8.

20.   Kavitha S. Pharmacognostical Evaluation and Standardisation of Ayurvedic Formulation Patoladi Kwatha Churna for Psoriasis. Research Journal of Pharmacy and Technology. 2020;13(3):1171-4.

21.   Taha MM, Al-Asady ZT. Evaluation of the Effectiveness of Antioxidants and TNF-α in Iraqi Patients with Psoriasis treated with Etanercept. Research Journal of Pharmacy and Technology. 2019;12(2):665-8.

22.   Sukare P, Bhattacharya R. Herbal plant used in Treatment of Psoriasis-A Systematic Review. Research Journal of Pharmacognosy and Phytochemistry. 2020;12(1):57-62.

23.   Staubach P, Zimmer S. Plaque psoriasis–more than a skin disorder. MedizinischeMonatsschrift fur Pharmazeuten. 2017;40(6):231-3. PMID: 29979560

24.   Blauvelt A. T-helper 17 cells in psoriatic plaques and additional genetic links between IL-23 and psoriasis. Journal of Investigative Dermatology. 2008; 1;128(5):1064-7.

25.   Asumalahti K, Ameen M, Suomela S, Hagforsen E, Michaelsson G, Evans J, Munro M, Veal C, Allen M, Leman J, Burden AD. Genetic analysis of PSORS1 distinguishes guttate psoriasis and palmoplantarpustulosis. Journal of investigative dermatology. 2003;1;120(4):627-32. DOI: 10.1046/j.1523-1747.2003.12094.x.

26.   KO HC, JWA SW, Song M, KIM MB, KWON KS. Clinical course of guttate psoriasis: Long‐term follow‐up study. The Journal of dermatology. 2010;37(10):894-9. DOI: 10.1111/j.1346-8138.2010.00871.x.

27.   Navarini AA, Burden AD, Capon F, Mrowietz U, Puig L, Köks S, Kingo K, Smith C, Barker JN, ERASPEN Network, Bachelez H. European consensus statement on phenotypes of pustular psoriasis. Journal of the European Academy of Dermatology and Venereology. 2017;31(11):1792-9. DOI: 10.1111/jdv.14386

28.   Sommer DM, Jenisch S, Suchan M, Christophers E, Weichenthal M. Increased prevalence of the metabolic syndrome in patients with moderate to severe psoriasis. Archives of dermatological research. 2007; 1;298(7):321. DOI: 10.1007/s00403-006-0703-z.

29.   Benjegerdes KE, Hyde K, Kivelevitch D, Mansouri B. Pustular psoriasis: pathophysiology and current treatment perspectives. Psoriasis (Auckland, NZ). 2016;6:131. DOI: 10.2147/PTT.S98954

30.   Micali G, Verzì AE, Giuffrida G, Panebianco E, Musumeci ML, Lacarrubba F. Inverse Psoriasis: From Diagnosis to Current Treatment Options. Clinical, Cosmetic and Investigational Dermatology. 2019; 12:953. DOI: 10.2147/CCID.S189000

31.   Singh RK, Lee KM, Ucmak D, Brodsky M, Atanelov Z, Farahnik B, Abrouk M, Nakamura M, Zhu TH, Liao W. Erythrodermic psoriasis: pathophysiology and current treatment perspectives. Psoriasis (Auckland, NZ). 2016;6: 93. DOI: 10.2147/PTT.S101232

32.   Ayala-Fontánez N, Soler DC, McCormick TS. Current knowledge on psoriasis and autoimmune diseases. Psoriasis (Auckland, NZ). 2016;6: 7. DOI: 10.2147/PTT.S64950

33.   Kormeili T, Lowe NJ, Yamauchi PS. Psoriasis: immunopathogenesis and evolving immunomodulators and systemic therapies; US experiences. British Journal of Dermatology. 2004;151(1):3-15. DOI: 10.1111/j.1365-2133.2004.06009.x.

34.   Berekmeri A, Mahmood F, Wittmann M, Helliwell P. Tofacitinib for the treatment of psoriasis and psoriatic arthritis. Expert review of clinical immunology. 2018;2;14(9):719-30. DOI: 10.1080/1744666X.2018.1512404.

35.   Surjushe A, Vasani R, Saple DG. Aloe vera: a short review. Indian journal of dermatology. 2008;53(4):163. DOI: 10.4103/0019-5154.44785.

36.   Saelee C, Thongrakard V, Tencomnao T. Effects of Thai medicinal herb extracts with anti-psoriatic activity on the expression on NF-κB signaling biomarkers in HaCaT keratinocytes. Molecules. 2011;16(5):3908-32. DOI: 10.3390/molecules16053908.

37.   Rout SK, Anwar S, Tripathy BC. Nanosilver Coated Coir Based Dielectric Materials with High K and Low Df for Embedded Capacitors and Insulating Material Applications–A Greener Approach. ACS Sustainable Chemistry & Engineering. 2019 21;7(4):3824-37.

38.   Parlapally S, Cherukupalli N, Bhumireddy SR, Sripadi P, Anisetti R, Giri CC, Khareedu VR, Reddy Vudem D. Chemical profiling and anti-psoriatic activity of methanolic extract of Andrographisnallamalayana JL Ellis. Natural Product Research. 2016; 2;30(11):1256-61. DOI: 10.1080/14786419.2015.1054825

39.   Qin JZ, Chaturvedi V, Denning MF, Choubey D, Diaz MO, Nickoloff BJ. Role of NF-κB in the apoptotic-resistant phenotype of keratinocytes. Journal of Biological Chemistry. 1999; 31;274(53):37957-64. DOI: 10.1074/jbc.274.53.37957

40.   Pandey SS, Jha AK, Kaur V. Aqueous extract of neem leaves in treatment of Psoriasis vulgaris. Indian Journal of Dermatology, Venereology, and Leprology. 1994; 1;60(2):63.

41.   Damevska K, Neloska L, Nikolovska S, Gocev G, Duma S. Complementary and alternative medicine use among patients with psoriasis. Dermatologic therapy. 2014;27(5):281-3. DOI: 10.1111/dth.12139

42.   Kapoor B, Kaur G, Gupta M, Gupta R. Indian medicinal plants useful in treatment of gout: a review for current status and future prospective. Asian J. Pharm. Clin. Res. 2017; 10:407. DOI:

43.   Bylka W, Znajdek-Awiżeń P, Studzińska-Sroka E, Brzezińska M. Centellaasiatica in cosmetology. Advances in Dermatology and Allergology/PostȩpyDermatologii I Alergologii. 2013;30(1):46. DOI: 10.5114/pdia.2013.33378.

44.   Amenta R, Camarda L, Di Stefano V, Lentini F, Venza F. Traditional medicine as a source of new therapeutic agents against psoriasis. Fitoterapia. 2000; 1;71: S13-20. DOI: 10.1016/s0367-326x(00)00172-6.

45.   Sunil Bavaskar, Mayur Bhurat, Vikram Mahale, Nasir Mohammad, Yogesh patil. Cassia fistula Linn. –A Phytopharmacological Review. Research J. Pharmacognosy and Phytochemistry 2011; 3(1): 10-13.

46.   Pattan SR, Dighe NS, Nirmal SA, Chavan PA, Bhawar SB, Jadhao N, Dighe SB. An Overview of Cassia fistula: Chemistry and Pharmacological Profile. Research Journal of Pharmacognosy and Phytochemistry. 2009;1(3):143-5.

47.   Rahman MA, Islam MS. Antioxidant, antibacterial and cytotoxic effects of the phytochemicals of whole Leucasaspera extract. Asian Pacific journal of tropical biomedicine. 2013;3(4):273. DOI: 10.1016/S2221-1691(13)60062-3.

48.   Dighe NS, Pattan SR, Nirmal SA, Dhasade VV, Dake SG, Shelar MU, Hole MB, Gaware V. A Review on Phytochemical and Pharmacological Profile of Cassia tora Linn. Research Journal of Pharmacognosy and Phytochemistry. 2009;1(3):173-6.

49.   Sabale P, Modi A, Sabale V. Curcuma longa Linn. A phytochemical and phytopharmacological review. Research Journal of Pharmacognosy and Phytochemistry. 2013;5(2):59-68.

50.   Reuter J, Wölfle U, Weckesser S, Schempp C. Which plant for which skin disease? Part 1: Atopic dermatitis, psoriasis, acne, condyloma and herpes simplex. JDDG: Journal der Deutschen DermatologischenGesellschaft. 2010;8(10):788-96. DOI: 10.1111/j.1610-0387.2010.07496.x.

51.   Daniyal M, Akram M, Zainab R, Munir N, Shah SM, Liu B, Wang W, Riaz M, Jabeen F. Progress and prospects in the management of psoriasis and developments in phyto‐therapeutic modalities. Dermatologic therapy. 2019;32(3):e12866. DOI: 10.1111/dth.12866. Epub 2019 Mar 18.

52.   Prasad V, Jain V, Girish D, Dorle AK. Wound-healing property of Momordicacharantia L. fruit powder. Journal of Herbal Pharmacotherapy. 2006;1;6(3-4):105-15. DOI: 10.1080/j157v06n03_05.

53.   Tse WP, Che CT, Liu K, Lin ZX. Evaluation of the anti-proliferative properties of selected psoriasis-treating Chinese medicines on cultured HaCaT cells. Journal of ethnopharmacology. 2006; 3;108(1):133-41. DOI: 10.1016/j.jep.2006.04.023. Epub 2006 May 5.

54.   Ross SM. Milk thistle (Silybummarianum): an ancient botanical medicine for modern times. Holistic nursing practice. 2008; 1;22(5):299-300. DOI: 10.1097/01.HNP.0000334924.77174.6d.

55.   Parlapally S, Cherukupalli N, Bhumireddy SR, Sripadi P, Anisetti R, Giri CC, Khareedu VR, Reddy Vudem D. Chemical profiling and anti-psoriatic activity of methanolic extract of Andrographisnallamalayana JL Ellis. Natural Product Research. 2016;2;30(11):1256-61. DOI: 10.1080/14786419.2015.1054825

56.   Wun C. Complementary Medicine-Navigating Volume Three. Journal of Complementary Medicine: CM, The. 2005;4(1):84. <;dn=893661027452168;res=IELHEA>

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