Author(s): V Jhansipriya Marabathuni, P. Dinesh, R. Ravikumar, P. Yamini, P. Sai Kiran, Sd. P.Hussain, Ch. M.M. Prasada Rao

Email(s): raj_mujoriya@live.com

DOI: 10.5958/2231-5659.2017.00015.7   

Address: V Jhansipriya Marabathuni1*, P. Dinesh1, R. Ravikumar1, P. Yamini1, P. Sai Kiran1, Sd. P.Hussain1, Ch. M.M. Prasada Rao
1Department of Pharmaceutics, Bellamkonda Institute of Technology and Sciences, Podili.
2Department of Pharm. Chemistry, QIS College of Pharmacy, Ongole
*Corresponding Author

Published In:   Volume - 7,      Issue - 2,     Year - 2017


ABSTRACT:
The buccal region of the oral cavity is an attractive target for administration of the drug of choice. Sustained release formulations have been developed and are gaining in popularity and medical acceptance. To increase bioavailability and prevent first pass metabolism of drug, Amlodipine besylate was embedded in sustained released buccal patch over period of 6 hour. The objective of present work was to characterize the effect of chitosan with PVP K-30 on water soluble drug by preparing mucoadhesive buccal patch. Each formulated batch was subjected to various evaluation parameters. The swelling percentage was found to be function of solubility of drug and PVP K-30. The mucoadhesive strength, vapour transmission and in-vitro released of water soluble drug through water insoluble chitosan base matrix were found satisfactorily. The AMB shows some suitability with those polymers.


Cite this article:
V Jhansipriya Marabathuni, P. Dinesh, R. Ravikumar, P. Yamini, P. Sai Kiran, Sd. P.Hussain, Ch. M.M. Prasada Rao. Chitosan Based Sustained Release Mucoadhesive Buccal Patches Containing Amlodipine Besylate (AMB). Asian J. Res. Pharm. Sci. 2017; 7(2): 97-104. doi: 10.5958/2231-5659.2017.00015.7


Recomonded Articles:

Author(s): Lakshmi Prasanna J., Deepthi B., Rama Rao N.

DOI:         Access: Open Access Read More

Author(s): Saudagar R. B., Sarika V. Khandbahale

DOI: 10.5958/2231-5659.2017.00005.4         Access: Open Access Read More

Author(s): AK Mohiuddin

DOI: 10.5958/2231-5659.2019.00004.3         Access: Closed Access Read More

Author(s): Girishchandra R. Mandake, Indrajit S. Patil, Omkar A Patil, Manoj M. Nitalikar, Shriniwas K Mohite

DOI: 10.5958/2231-5659.2018.00012.7         Access: Open Access Read More

Author(s): Pratibha Gavarkar, Pramod Patil, Akshay Sutar, Shridhar Rasal, Dyaneshwar Surwase

DOI: 10.5958/2231-5659.2016.00029.1         Access: Open Access Read More

Author(s): Pramod Patil, Someshwara Rao B, Suresh V Kulkarni, Basavaraj, Chetan Surpur , Anand Ammanage

DOI:         Access: Open Access Read More

Author(s): Roshani Bhalerao, Akshay Patil, Dinesh Rishipathak, Sanjay Kshirsagar

DOI: 10.5958/2231-5659.2017.00029.7         Access: Open Access Read More

Author(s): Deepak Prashar, Dharmesh Sharma

DOI:         Access: Open Access Read More

Author(s): Sana Banu, Syeda Ayesha Farheen

DOI: 10.5958/2231-5659.2019.00015.8         Access: Closed Access Read More

Author(s): Aduema W., Amah A. K, Wariso A.C

DOI: 10.5958/2231-5659.2018.00001.2         Access: Open Access Read More

Author(s): Sourabh S. Baghel, Sonal Dangi, Prashant Soni, Priya Singh, Yogesh Shivhare

DOI:         Access: Open Access Read More

Author(s): Rajendra Jangde

DOI:         Access: Open Access Read More

Author(s): D.M. Shinkar, Aarif S. Khatik, R.B. Saudagar

DOI: 10.5958/2231-5659.2016.00022.9         Access: Open Access Read More

Author(s): Sudhir Sawant, Ramesh Yamgar

DOI:         Access: Open Access Read More

Author(s): S. More, T. Ghadge, S. Dhole

DOI:         Access: Open Access Read More

Author(s): Mohammad Yaqub Khan, Irfan Aziz, Imtiyaz Ahmad, Maryada Roy

DOI: 10.5958/2231-5659.2015.00029.6         Access: Open Access Read More

Author(s): Swapnil R. Lahamage, Avinash B. Darekar, Ravindra B. Saudagar

DOI: 10.5958/2231-5659.2016.00008.4         Access: Open Access Read More

Asian Journal of Research in Pharmaceutical Sciences (AJPSci) is an international, peer-reviewed journal, devoted to pharmaceutical sciences....... Read more >>>

RNI: Not Available                     
DOI: 10.5958/2231-5659 


Recent Articles




Tags