Author(s): Nawale Sejal Navnath

Email(s): Nawalesejal227@gmail.com

DOI: 10.52711/2231-5659.2024.00030   

Address: Nawale Sejal Navnath
Pravara Rural College of Pharmacy, Pravaranagar
*Corresponding Author

Published In:   Volume - 14,      Issue - 2,     Year - 2024


ABSTRACT:
Known by many as the “tree of life” or the “miracle tree,” Moringa oleifera is a remarkable herbal plant with a wide range of therapeutic and non-medicinal effects. Historically, M. oleifera has been used to treat a wide range of illnesses, including cancer, heart disease, liver disease, ulcers, pain, and inflammation. Pharmacological investigations have validated the hepatoprotective, cardioprotective, and anti-inflammatory properties present in extracts obtained from different sections of the Moringa oleifera plant. Remarkably, more than a hundred chemicals have been described thus far, and bioactive components have been found in every portion of the plant. Among other things, the plant has high concentrations of alkaloids, flavonoids, anthraquinones, vitamins, glycosides, and terpenes. Furthermore, strong hepatoprotective, anticancer, antihypertensive, antioxidant, and nutritional properties have been revealed by the discovery of unique compounds in the plant, such as muramoside A&B and niazimin A&B. This review highlights the long-standing and noteworthy benefits of moringa, exploring its pharmacological properties, phytopharmaceutical formulations, clinical assessments, toxicity profile, and other uses. In order to encourage additional study, it also seeks to clarify the plant’s economic and phytopharmaceutical uses. The review notes that despite this thorough examination, many traditional use of moringa remain untested by science. As a result, the study recommends more investigation to decipher the plant’s physiological processes with the goal of identifying and isolating the active or cooperative chemicals responsible for its therapeutic qualities.


Cite this article:
Nawale Sejal Navnath. Moringa oleifera: A Review on Medicinal properties and their Commercial Applications. Asian Journal of Research in Pharmaceutical Sciences. 2024; 14(2):125-8. doi: 10.52711/2231-5659.2024.00030

Cite(Electronic):
Nawale Sejal Navnath. Moringa oleifera: A Review on Medicinal properties and their Commercial Applications. Asian Journal of Research in Pharmaceutical Sciences. 2024; 14(2):125-8. doi: 10.52711/2231-5659.2024.00030   Available on: https://ajpsonline.com/AbstractView.aspx?PID=2024-14-2-14


REFERENCES:
1.    J.L.Rockwood, B.G. Anderson, D.A. Casamatta. Potential uses of Moringa oleifera and an examination of antibiotic efficacy conferred by M. oleifera Seed and leaf extracts using crude extraction techniques available to underserved indigenous populations. Int. J. Phytothearpy Res.  2013; 3: 61–71.
2.    J.N. Kasolo, G.S. Bimenya, L. Ojok, J. Ochieng, J.W. Ogwal-okeng. Phytochemicals and uses of Moringa oleifera leaves in Ugandan rural Communities. J. Med. Plants Res. 2010; 4: 753–757.
3.    T. Mutiara Titi, E.S.W. Estiasih. Effect lactagoguemoringa leaves (Moringa Oleifera Lam) powder in rats. J. Basic Appl. Sci. Res. 2013; 3: 430–434.
4.    M.E. Cerf. Beta cell dysfunction and insulin resistance. Front. Endocrinol. 2013; 4: 1–12.
5.    S.M. Divi, R. Bellamkonda, S.K. Dasireddy. Evaluation of antidiabetic And antihyperlipedemic potential of aqueous extract of Moringa oleifera In fructose fed insulin resistant and STZ induced diabetic wistar rats: a Comparative study. Asian J. Pharm. Clin. Res. 2012; 5: 67–72.
6.    E. Wright, J.L. Scism-Bacon, L.C. Glass. Oxidative stress in type 2 diabetes: the role of fasting and postprandial glycaemia. Int. J. Clin. Pract. 2006; 60: 308–314.
7.    H. Kaneto, Y. Kajimoto, J. Miyagawa, T. Matsuoka, Y. Fujitani, Y. Umayahara, T. Hanafusa, Y. Matsuzawa, Y. Yamasaki, M. Hori. Beneficial effects Of antioxidantsin diabetes: possible protection of pancreatic-cells against Glucose toxicity. Diabetes. 1999; 48: 2398–2406.
8.    M. Prentki, C.J. Nolan. Islet  cell failure in type 2 diabetes. J. Clin. Invest. 2006; 116: 1802–1812.
9.    N. Kamalakkannan, P.S.M. Prince. Antihyperglycaemic and antioxidant Effect of rutin, a polyphenolic flavonoid, in streptozotocin-induced diabetic Wistar rats. Basic Clin. Pharmacol. Toxicol. 2006; 98: 97–103.
10.    D. Aronson, E.J. Rayfield. How hyperglycemia promotes atherosclerosis: Molecular mechanisms. Cardiovasc. Diabetol. 2002; 1: 1.
11.    P. Chumark, P. Khunawat, Y. Sanvarinda, S. Phornchirasilp, N.P. Morales, L. Phivthongngam, P. Ratanchamnong, S. Srisawat, K.U. Pongrapeeporn. The in vitro and ex vivo antioxidant properties, hypolipidaemic and Antiatherosclerotic activities of water extract of Moringa oleifera Lam. Leaves. J. Ethnopharmacol. 2008; 116: 439–446.
12.    M. Mbikay. Therapeutic potential of Moringa oleifera leaves in chronic Hyperglycemia and dyslipidemia: a review. Front. Pharmacol. 2012; 3: 1–12.
13.    A.L. Al-Malki, H.A. El Rabey. The antidiabetic effect of low doses of Moringa oleifera Lam. Seeds on streptozotocin induced diabetes and diabetic nephropathy in male rats. Biomed. Res. Int. 2015: 1–13.
14.    S. Lalas, J. Tsaknis. Characterization of Moringa oleifera seed oil variety Periyakulam-1. J. Food Compos. Anal. 2002; 15: 65–77
15.    P Jayasri M Sreeja N Keerthi J Yeshashwini J Praveen. Moringa oleifera: A review on nutritive importance and its potential use as nutraceutical plant. J Med Plants Stud. 2021921522
16.    P Sharma J Wichaphon W Klangpetch. Antimicrobial and antioxidant activities of defatted Moringa oleifera seed meal extract obtained by ultrasound-assisted extraction and application as a natural antimicrobial coating for raw chicken sausages. Int J Food Microbiol. 2020; 3322 10877010.1016/j.ijfoodmicro.2020.108770
17.    A Anzano B De Falco M Ammar A Ricciardelli L Grauso M Sabbah. Chemical Analysis and Antimicrobial Activity of Moringa oleifera Lam Leaves and Seeds. Mol. 20222724892010.3390/molecules27248920
18.    BL Dinesha U Nidoni CT Ramachandra N Naik KB Sankalpa. Effect of extraction methods on physicochemical, nutritional, antinutritional, antioxidant and antimicrobial activity of Moringa (Moringa oleifera Lam.) seed kernel oil. J Appl Nat Sci. 2018; 10128795
19.    JS Moodley SBN Krishna K Pillay P Govender. Green synthesis of silver nanoparticles from Moringa oleifera leaf extracts and its antimicrobial potential.  Adv Nat Sci Nanosci Nanotechnol. 2018; 9119
20.    EJ Park S Cheenpracha LC Chang TP Kondratyuk JM Pezzuto. Inhibition of lipopolysaccharide-induced cyclooxygenase-2 and inducible nitric oxide synthase expression by 4-[(2’-O-acetyl-α-L-rhamnosyloxy) benzyl]isothiocyanate from Moringa oleifera. Nutr Cancer. 201163697182
21.    DA Boggs JR Palmer LA Wise D Spiegelman MJ Stampfer L. Adams-Campbell Fruit and vegetable intake in relation to risk of breast cancer in the black women’s health study. Am J Epidemiol. 201017211126879
22.    JH Fowke FL Chung JF Qi D Cai Q. Conaway Urinary isothiocyanate levels, Brassica, and human breast cancer. Cancer Res. 2003631439806
23.    JW Fahey AT Zalcmann P Talalay. The chemical diversity and distribution of glucosinolates and isothiocyanates among plants. Phytochemistry. 2001561551
24.    N Chhikara A Kaur S Mann MK Garg SA Sofi A Panghal.  Bioactive compounds, associated health benefits and safety considerations of Moringa oleifera L.: an updated review. Nutr Food Sci. 202151225577
25.    P Pagadala V Shankar. Moringa olifera: Constituents and protective effects on organ systems. Physiol Pharmacol. 20202428290
26.    S. Lalas, J. Tsaknis. Characterization of Moringa oleifera seed oil variety Periyakulam-1. J. Food Compos. Anal. 2002; 15: 65–77.
27.    J. Fahey. Moringa oleifera: a review of the medical evidence for its nutritional, therapeutic, and prophylactic properties.  Trees Life J. 2005; 1.
28.    M. Lurling, W. Beekman. Anticyanobacterial activity of Moringa oleifera Seeds. J. Appl. Phycol. 2010; 23: 503–510.
29.    M.E. Sengupta, B. Keraita, A. Olsen, O.K. Boateng, S.M. Thamsborg, G.R. Pálsdóttir, A. Dalsgaard. Use of Moringa oleifera seed extracts to Reduce helminth egg numbers and turbidity in irrigation water. Water Res. 2012; 46: 3646–3656.
30.    S. Suhartini, N. Hidayat, E. Rosaliana. Influence of powdered Moringa oleifera seeds and natural filter media on the characteristics of tapioca Starch wastewater. Int. J. Recycl. Org. Waste Agric. 2013; 2: 1–11.
31.    K. Ravikumar, A.K. Sheeja. Heavy metal removal from water using Moringa oleifera seed coagulant and double filtration. Int. J. Sci. Eng.Res. 2013; 4: 10–13.
32.    T.R. Santos, M.F. Silva, L. Nishi, A.M. Vieira, M.R. Klein, M.B. Andrade, M.F. Vieira, R. Bergamasco. Development of a magnetic coagulant based On Moringa oleifera seed extract for water treatment. Env. Sci. Pollut. Res. 2016:  1–9.
33.    A.K. Arise, R.O. Arise, M.O. Sanusi, O.T. Esan, S.A. Oyeyinka. Effect of Moringa oleifera flower fortification on the nutritional quality and sensory Properties of weaning food. Croat. J. Food Sci. Technol. 2014; 6: 65–71.
34.    O.E. Adejumo, A.L. Kolapo, A.O. Folarin. Moringa oleifera Lam. (Moringaceae) grown in Nigeria: in vitro antisickling activity on deoxygenated erythrocyte cells. J. Pharm. Bioall. Sci. 2012; 4: 118–122.

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