Author(s): D B Thorat, Shivkumar B, Nagendra Rao, Mohankumar K M

Email(s): dattatraya_thorat@rediffmail.com , shivkumarb@gmail.com , nagendra.rao@gmail.com , kmohankumar124@gmail.com

DOI: 10.52711/2231-5659.2021.00034   

Address: D B Thorat1, Shivkumar B2, Nagendra Rao2, Mohankumar K M2
1PRES Institute of Pharmacy, Loni, Tal - Rahata, Dist - Ahmednagar (M S), India.
2SCS College of Pharmacy, Harpanhalli, Dhavangiri, District (K S), India.
*Corresponding Author

Published In:   Volume - 11,      Issue - 3,     Year - 2021


ABSTRACT:
Ten different 2, 7-disubstituted [1, 3, 4]-thiadiazolo [2, 3-b] quinazolin-5(4H)-ones were synthesized by action of 3-amino-2-mercaptoquinazolin-4(3H)-ones with various aliphatic and aromatic acid chloride in the presence of phosphorousoxy chloride. The newly synthesized compounds have been characterized by their analytical and spectral (IR, 1HNMR and Mass) properties. Further, they have been screened for their anti-inflammatory (in vitro and in vivo) by standard method.


Cite this article:
D B Thorat, Shivkumar B, Nagendra Rao, Mohankumar K M. Synthesis and Evaluation of new 4(3H)-quinazolinones derivatives as potential Anti-Inflammatory agents. Asian Journal of Research in Pharmaceutical Sciences. 2021; 11(3):213-8. doi: 10.52711/2231-5659.2021.00034

Cite(Electronic):
D B Thorat, Shivkumar B, Nagendra Rao, Mohankumar K M. Synthesis and Evaluation of new 4(3H)-quinazolinones derivatives as potential Anti-Inflammatory agents. Asian Journal of Research in Pharmaceutical Sciences. 2021; 11(3):213-8. doi: 10.52711/2231-5659.2021.00034   Available on: https://ajpsonline.com/AbstractView.aspx?PID=2021-11-3-6


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