Author(s): Blessy Jayamon, Bindu Krishna Kosireddy, Vinod Kumar Mugada, Satya Sai Srinivas Allada, Srinivasa Rao Yarguntla

Email(s): blessyjayamon18@gmail.com

DOI: 10.52711/2231-5659.2024.00019   

Address: Blessy Jayamon1*, Bindu Krishna Kosireddy1, Vinod Kumar Mugada1, Satya Sai Srinivas Allada1, Srinivasa Rao Yarguntla2
1Department of Pharmacy Practice, Vignan Institute of Pharmaceutical Technology, Visakhapatnam, Andhra Pradesh, India.
2Department of Pharmaceutics, Vignan Institute of Pharmaceutical Technology, Visakhapatnam, Andhra Pradesh, India.
*Corresponding Author

Published In:   Volume - 14,      Issue - 2,     Year - 2024


ABSTRACT:
Kikuchi-Fujimoto disease (KFD) is a rare form of lymphadenitis that primarily affects young women in Japan and other parts of Asia. It is caused by unknown agents, possibly viruses that trigger an autoimmune response in genetically susceptible individuals. KFD is often misdiagnosed due to its resemblance to other benign and malignant conditions, including SLE-related lymphadenitis and lymphoma. Diagnosis of KFD requires a lymph node biopsy, which reveals characteristic features such as histiocytic necrotizing lymphadenitis. Additional diagnostic tests, including skin biopsy, MRI, and cerebrospinal fluid analysis, can aid in confirming the diagnosis. KFD is self-limiting, and most patients recover within a few months with symptomatic treatment. However, early intervention with corticosteroids and hydroxychloroquine is crucial for effective management, particularly in cases with extra-nodal involvement or neurological symptoms. Lymph node removal can also be an effective therapeutic measure, and Hemophagocytic lymphohistiocytosis (HLH), a potential complication of KFD, is managed with a combination of immunoglobulins and steroids. While KFD is a benign condition, its diagnosis and treatment can be challenging, requiring close monitoring and follow-up.


Cite this article:
Blessy Jayamon, Bindu Krishna Kosireddy, Vinod Kumar Mugada, Satya Sai Srinivas Allada, Srinivasa Rao Yarguntla. Kikuchi-Fujimoto Disease: A Rare Lymphadenitis with Diagnostic Challenges and Treatment Considerations. Asian Journal of Research in Pharmaceutical Sciences. 2024; 14(2):129-6. doi: 10.52711/2231-5659.2024.00019

Cite(Electronic):
Blessy Jayamon, Bindu Krishna Kosireddy, Vinod Kumar Mugada, Satya Sai Srinivas Allada, Srinivasa Rao Yarguntla. Kikuchi-Fujimoto Disease: A Rare Lymphadenitis with Diagnostic Challenges and Treatment Considerations. Asian Journal of Research in Pharmaceutical Sciences. 2024; 14(2):129-6. doi: 10.52711/2231-5659.2024.00019   Available on: https://ajpsonline.com/AbstractView.aspx?PID=2024-14-2-3


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Asian Journal of Research in Pharmaceutical Sciences (AJPSci) is an international, peer-reviewed journal, devoted to pharmaceutical sciences....... Read more >>>

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DOI: 10.52711/2231-5659 


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