Author(s): Bindesh Thakkar, Kartavya Pawar, Rahul Patil, Ashwini Bhoir, Payaam Vohra

Email(s): payaamvohra@gmail.com

DOI: 10.52711/2231-5659.2024.00010   

Address: Bindesh Thakkar1, Kartavya Pawar1, Rahul Patil1, Ashwini Bhoir1, Payaam Vohra2*
1Konkan Gyanpeeth Rahul Dharkar College of Pharmacy and Research Instiute, Karjat - 410201, India.
2Department of Pharmacology, NIPER SAS Nagar, Punjab, India.
*Corresponding Author

Published In:   Volume - 14,      Issue - 1,     Year - 2024


ABSTRACT:
Liquisolid Technology aims to make drug entities more soluble that have low solubility and low permeability, through the cosolvency theory in a reasonably simple setup that doesn't require expensive technology. A non-volatile solvent is used to dissolve a medicine into molecular dispersion, which is then converted into a powder that has the appearance of being dry and is easily compressible. Extrudates are produced from the material by extrusion using an extruder. To create spherical particles known as Pellets, the extrudates are placed beneath the spheronizer. These pellets or granules can be filled in capsules or can be compacted into tablets according to their dose and can be utilized. Various evaluation parameters like Carr`s Index, Angle of Repose, FTIR, etc was studied. Overall, the study demonstrated that the liqui-pellet might improve a liquisolid formulation's poor flowability, which is thought to be a significant development in the concept's commercial viability. The current review aims to unfurl the utilization of liquisolid technology as a potential drug delivery system for BCS class 2 and 3 drugs.


Cite this article:
Bindesh Thakkar, Kartavya Pawar, Rahul Patil, Ashwini Bhoir, Payaam Vohra. Liquisolids: A Modernistic approach in Drug Delivery System. Asian Journal of Research in Pharmaceutical Sciences. Sci. 2024; 14(1):63-0. doi: 10.52711/2231-5659.2024.00010

Cite(Electronic):
Bindesh Thakkar, Kartavya Pawar, Rahul Patil, Ashwini Bhoir, Payaam Vohra. Liquisolids: A Modernistic approach in Drug Delivery System. Asian Journal of Research in Pharmaceutical Sciences. Sci. 2024; 14(1):63-0. doi: 10.52711/2231-5659.2024.00010   Available on: https://ajpsonline.com/AbstractView.aspx?PID=2024-14-1-10


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