Author(s): Kishan D. Patel, Chhaganbhai N. Patel, Grishma M. Patel

Email(s): kishan_birju@yahoo.com

DOI: 10.5958/2231-5659.2015.00001.6   

Address: Kishan D. Patel1*, Chhaganbhai N. Patel2, Grishma M. Patel3
1Shree S. K. Patel College of Pharmaceutical Education & Research, Gujarat, India.
2Shri Sarvajanic Pharmacy College, Gujarat, India.
3K. B. Institute of Pharmaceutical Education & Research, Gujarat, India.
*Corresponding Author

Published In:   Volume - 5,      Issue - 1,     Year - 2015


ABSTRACT:
A new series of 4-((2,4-dioxathiazolidin-5-ylidine)methyl)substituted benzene sulphonamide was prepared. The purity of the new compounds was checked by TLC and elucidation of their structures was confirmed by IR, 1H-NMR and mass spectroscopy. All the target compounds were evaluated for their in vivo antidiabetic activity on male Wistar rats by Oral Glucose Tolerance Test (OGTT) method using pioglitazone as standard. Amongst all, compound K17 and K18 exhibited more prominent antidiabetic activity. The results were statistically verified for its significance.


Cite this article:
Kishan D. Patel, Chhaganbhai N. Patel, Grishma M. Patel. Synthesis and Antidiabetic Activity of Novel 4-((2,4-Dioxothiazolidin-5-ylidene)methyl)Substituted Benzene Sulphonamide. Asian J. Res. Pharm. Sci. 5(1): Jan.-March 2015; Page 1-7. doi: 10.5958/2231-5659.2015.00001.6


Recomonded Articles:

Author(s): Mohd. Yaqub Khan, Maryada Roy, Imtiyaz Ahmad, Irfan Aziz, Manju Panday

DOI: 10.5958/2231-5659.2015.00024.7         Access: Open Access Read More

Author(s): Namdeo Shinde, Nagesh Aloorkar, Ajit Kulkarni, Bhaskar Bangar, Suyog Sulake, Pratik Kumbhar

DOI:         Access: Open Access Read More

Author(s): Rajashri R. Kulkarni, Dipti G. Phadtare, Ravindra B. Saudagar

DOI: 10.5958/2231-5659.2016.00019.9         Access: Open Access Read More

Author(s): Muhammed Jameel VP, Ravikumar, Narayanaswamy VB

DOI: 10.5958/2231-5659.2016.00017.5         Access: Open Access Read More

Author(s): AK Mohiuddin

DOI: 10.5958/2231-5659.2019.00004.3         Access: Closed Access Read More

Author(s): Ismail Hussain, Ravikumar, Narayanaswamy VB, Injamamul Haque, Mohibul Hoque

DOI: 10.5958/2231-5659.2016.00030.8         Access: Open Access Read More

Author(s): Darekar A. B. , Zope Janhavi S. , Saudagar R. B.

DOI: 10.5958/2231-5659.2016.00013.8         Access: Open Access Read More

Author(s): Girishchandra R. Mandake, Indrajit S. Patil, Omkar A Patil, Manoj M. Nitalikar, Shriniwas K Mohite

DOI: 10.5958/2231-5659.2018.00012.7         Access: Open Access Read More

Author(s): Sushil D. Patil, Prajkta Varpe, Sayali Chaure, Siddharth B. Bhalerao, Sanjay Kshirsagar

DOI: 10.5958/2231-5659.2017.00034.0         Access: Open Access Read More

Author(s): Rohan R. Vakhariya, Swati S. Talokar, V. R. Salunkhe, C. S. Magdum

DOI: 10.5958/2231-5659.2017.00008.X         Access: Open Access Read More

Author(s): P. Thamarai Selvi, M. Senthil Kumar, R. Rajesh, T. Kathiravan

DOI:         Access: Open Access Read More

Author(s): Priya Rahade, Sandeep Sonawane, Atharva Bhalerao, Sanjay Kshirsagar

DOI:         Access: Open Access Read More

Author(s): K. Vijayabhaskar, Macharla Sravanprasad, Goli.venkateshwarlu, P. Suvarna Devi, K. Hemanth Kumar, J. Sunil

DOI:         Access: Open Access Read More

Author(s): Roshani Bhalerao, Akshay Patil, Dinesh Rishipathak, Sanjay Kshirsagar

DOI: 10.5958/2231-5659.2017.00029.7         Access: Open Access Read More

Asian Journal of Research in Pharmaceutical Sciences (AJPSci) is an international, peer-reviewed journal, devoted to pharmaceutical sciences....... Read more >>>

RNI: Not Available                     
DOI: 10.5958/2231-5659 


Recent Articles




Tags