A Critical Analysis of Medicinal plants for Anti-Depressant action with their Phyto-Constituent and Mechanism of Action

Shanti Bhushan Mishra; Priya Mishra

doi:10.52711/2231-5659.2024.00004

Asian Journal of Research in Pharmaceutical Sciences

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2231-5659 (Online)
2231-5640 (Print)

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A Critical Analysis of Medicinal plants for Anti-Depressant action with their Phyto-Constituent and Mechanism of Action

Author(s): Shanti Bhushan Mishra, Priya Mishra

Email(s): shantipharma15@gmail.com

DOI: 10.52711/2231-5659.2024.00004

Address: Shanti Bhushan Mishra1*, Priya Mishra2
1Department of Pharmacognosy, United Institute of Pharmacy, Prayagraj 211010, India.
2Department of Pharmacology, United Institute of Pharmacy, Prayagraj 211010, India.
*Corresponding Author

Published In: Volume - 14, Issue - 1, Year - 2024

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ABSTRACT:
Depression or stress refers to a state of sad feelings and loss of interest in pleasurable activities characterized by retardation of thoughts and actions, appetite and weight changes, restlessness as well as in sleep disturbance. All the current evidences implicate alteration in the firing pattern of a subset of biogenic amines in the central nervous system. There are adequate number of synthetic drugs used to treat depression as standard treatment for clinically depressed patient, however only 30% of patients respond satisfactorily to the existing medicines and the remaining do not attain full recovery. Many scientists are investigating on herbal drugs for mitigating this disorder that shown antidepressant properties by virtue of synergistic effect of their phyto constituents. In this review article we emphasize to give an outline of certain medicinal plants with their constituents and mechanism of action which have been explored for their antidepressant action.

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Cite this article:
Shanti Bhushan Mishra, Priya Mishra. A Critical Analysis of Medicinal plants for Anti-Depressant action with their Phyto-Constituent and Mechanism of Action. Asian Journal of Research in Pharmaceutical Sciences. Sci. 2024; 14(1):19-6. doi: 10.52711/2231-5659.2024.00004

Cite(Electronic):
Shanti Bhushan Mishra, Priya Mishra. A Critical Analysis of Medicinal plants for Anti-Depressant action with their Phyto-Constituent and Mechanism of Action. Asian Journal of Research in Pharmaceutical Sciences. Sci. 2024; 14(1):19-6. doi: 10.52711/2231-5659.2024.00004 Available on: https://ajpsonline.com/AbstractView.aspx?PID=2024-14-1-4

REFERENCES:
1.   P. Thamarai Selvi, M. Senthil Kumar, R. Rajesh, T. Kathiravan. Antidepressant activity of ethanolic extract of leaves of Centella asiatica. Linn by In vivo methods. Asian J. Res. Pharm. Sci. 2012; 2(2): 76-79.
2.   Uppala PK, Murali Krishna B, Kumar KA, Ramji V. Experimental Evaluation of Antidepressant activity of Aqueous and Methanolic Leaf and Shoot Extracts of Ageratum conyzoides Linn in Mice. Asian J. Pharm. Res. 2016; 6(3): 153-158. doi: 10.5958/2231-5691.2016.00022.8.
3.   Rabiei Z, Rabiei S. A review on antidepressant effect of medicinal plants. Bangladesh J Pharmacol. 2017; 12: 1-11.
4.   Avani Shewale, N. S. Naikwade, P. L. Ladda. Antidepressant activity of Chrysanthemum morifolium Linn in mice. Asian J. Res. Pharm. Sci. 2019; 9(4): 260-266. doi: 10.5958/2231-5659.2019.00040.7
5.   Kamalipour M, Akhondzadeh S, Rezazadeh S. Herbal medicines in the treatment of depression and anxiety. J Med Plants. 2008; 7: 1-6.
6.   Maes M, Galecki P, Chang Y, Berk M. A review on the oxidative and nitrosative stress (O & NS) pathways in major depression and their possible contribution to the (neuro) degenerative processes in that illness. Prog Neuropsychopharmacol Biol Psychiatry. 2011; 35: 676–92.
7.   Richelson E. Pharmacology of antidepressants-characteristic of the ideal drug. Mayo Clin Proceed. 1994; 69: 1069-81.
8.   Sheline YI, Gado MH, Kraemer HC. Untreated depression and hippocampal volume loss. American Journal of Psychiatry. 2003 Aug 1;160(8):1516-8.
9.   Teo AR, Choi H, Valenstein M. Social relationships and depression: ten-year follow-up from a nationally representative study. PloS one. 2013 Apr 30;8(4):e62396.
10.   Vreeburg SA, Hoogendijk WJ, van Pelt J, DeRijk RH, Verhagen JC, van Dyck R, Smit JH, Zitman FG, Penninx BW. Major depressive disorder and hypothalamic-pituitary-adrenal axis activity: results from a large cohort study. Archives of general psychiatry. 2009 Jun 1;66(6):617-26.
11.   Lampe IK, Hulshoff Pol HE, Janssen J, Schnack HG, Kahn RS, Heeren TJ. Association of depression duration with reduction of global cerebral gray matter volume in female patients with recurrent major depressive disorder. American Journal of Psychiatry. 2003 Nov 1;160(11):2052-4.
12.   Taylor WD, MacFALL JR, Payne ME, McQUOID DR, Steffens DC, Provenzale JM, Krishnan KR. Orbitofrontal cortex volume in late life depression: influence of hyperintense lesions and genetic polymorphisms. Psychological Medicine. 2007 Dec;37(12):1763-73.
13.   Delgado PL, Miller HL, Salomon RM, Licinio J, Krystal JH, Moreno FA, Heninger GR, Charney DS. Tryptophan-depletion challenge in depressed patients treated with desipramine or fluoxetine: implications for the role of serotonin in the mechanism of antidepressant action. Biological psychiatry. 1999 Jul 15;46(2):212-20.
14.   Martínez P, Vöhringer PA, Rojas G. Barreiras de acesso a tratamento para mães com depressão pós-parto em centros de atenção primária: Um modelo preditivo. Rev Lat Am Enfermagem. (2016) 24:e2675. doi: 10.1590/1518-8345.0982.2675
15.   Nie Z, Vairavan S, Narayan VA, Ye J, Li QS. Predictive modeling of treatment resistant depression using data from STARD and an independent clinical study. PLoS ONE. (2018) 13:e0197268. doi: 10.1371/journal.pone.0197268
16.   Colaianna M, Schiavone S, Zotti M, Tucci P, Morgese MG, Bäckdahl L, et al. Neuroendocrine profile in a rat model of psychosocial stress: relation to oxidative stress. Antioxida Redox Signal. (2013) 18:1385–99. doi: 10.1089/ars.2012.4569
17.   Lu J, Zhou H, Meng D, Zhang J, Pan K, Wan B, et al. Tanshinone IIA Improves depression-like behavior in mice by activating the ERK-CREB-BDNF signaling pathway. Neuroscience. (2020) 430:1–11. doi: 10.1016/j.neuroscience.2020.01.026
18.   McVey Neufeld KA, Bienenstock J, Bharwani A, Champagne-Jorgensen K, Mao YK, West C, et al. Oral selective serotonin reuptake inhibitors activate vagus nerve dependent gut-brain signalling. Sci Rep. (2019) 9:14290. doi: 10.1038/s41598-019-50807-8
19.   P. Thamarai Selvi, M. Senthil Kumar, R. Rajesh, T. Kathiravan. Antidepressant activity of ethanolic extract of leaves of Centella asiatica. Linn by In vivo methods. Asian J. Res. Pharm. Sci. 2(2): April-June 2012; Page 76-79.
20.   Ferdous A. Jabir, Sundus K. Hamzah. Evaluation of Anti-Depressant Activity of Petroleum Ether Extract of Rosa centifolia in Swiss Albino Mice. Research J. Pharm. and Tech 2018; 11(5):2000-2005. doi: 10.5958/0974-360X.2018.00372.4
21.   Anantha Lakshmi J, Satyavthi D. Evaluation of Anti-Depressant and MAO Inhibitory Activity of Rhodiola rhodantha rhizome methanolic extract. Research J. Pharm. and Tech. 8(3): Mar., 2015; Page 310-315. doi: 10.5958/0974-360X.2015.00051.7
22.   Dheeraj Ahirwar, Bharti Ahirwar. Antidepressant effect of Nigella sativa in stress-induced depression. Research J. Pharm. and Tech. 2020; 13(4):1611-1614.
23.   Sudhir Patil, Prakash Nargatti, Tabassum Shikalgar, Nilofar Naikwade. Evaluation of Antidepressant activity of Ficus carica leaves extract in experimental animals. Research J. Pharm. and Tech 2021; 14(3):1267-1273.
24.   Kishu Tripathi. Herbs for Depression: A Review. Research J. Science and Tech. 2009; 1(2): 55-62.

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DOI: 10.52711/2231-5659