P. Kumaravel, AK. Prabhakaran, G. Melchias, A. Edward, P. Natarajan, S. Sathishkumar
P. Kumaravel1*, AK. Prabhakaran1, G. Melchias2, A. Edward3, P. Natarajan1, S. Sathishkumar1
1Department of Biotechnology, Vysya College, Salem- 636 103, Tamil Nadu, India.
2Department of Botany, St. Joseph's College, Tiruchirappalli- 620 002, Tamil Nadu, India.
3Department of Biotechnology, St. Joseph's College, Tiruchirappalli- 620 002, Tamil Nadu, India.
Volume - 4,
Issue - 1,
Year - 2014
Monosodium glutamate was administrated subcutaneously to wistar rats for 60 days and circadian rhythms of Nitric oxide and Vitamin-C were studied. Advanced acrophase of nitric oxide and delayed acrophase of antioxidants were found in experimental groups as compared with control rats. Constant light exposed rats showed increased mesor of nitric oxide and decreased mesor of antioxidants. Ampiltude and mesor values of these rhythms were found to be altered in experimental group rats. Constant light and monosodium glutamate treated rats shows cortical edema and microcyclic degeneration in brain was observed.
Cite this article:
P. Kumaravel, AK. Prabhakaran, G. Melchias, A. Edward, P. Natarajan, S. Sathishkum. Monosodium glutamate exposure alters histopathological and biochemical variables in rats under constant light. Asian J. Res. Pharm. Sci. 4(1): Jan.-Mar. 2014; Page 01-04.