Three Allied Herbal Aid used in Dentistry


Dr Deepak Prashar

Department of Pharmacy, LR Institute of Pharmacy, Solan (H.P), India

*Corresponding Author E-mail:



There are large numbers of herbal dental products used in the present scenario. In dentistry these products are used as an alternate in association with regular products. The efficiency of these products is being accomplished through number of randomized clinical trials (RCT) and pharmacognostic specifications. The present diminutive review focuses on the three allied herbal aid used in dentistry.


KEYWORDS: Herbal, Herbal Aids, Dental, Allied.




In dentistry numbers of products are available in the market. All these products and formulations are available OTC and hence its economical outcomes are more. Toothpaste, mouthwashes, dentifrices, gargles etc have become an important prospect of our daily life. All these available resources in dentistry are more related to cosmeceuticals than pharmaceuticals. In the present scenario, the formulations based on herbals are much more accepted by the consumers. The present review tries to highlight the three available allied herbs which are directly or indirectly boons the dentistry.



There is a great importance of these herbal aids in pharmacy preparations and its dental utilization. The parts used and the chemical constituents utilized in these agents are enormolous.



Dental Therapy with Allied Herbs:

·         Trachyspermum ammi (Ajowan): Khan et al.,1 through their study isolated the novel compound (4aS, 5R, 8aS) 5, 8a-di-1-propyl-octahydronaphthalen-1-(2H)-one, from the seeds of T. ammi which has the anti-caries activity against the Streptococcus mutans. Javed et al.,2 also reported through their studies about the anti-microbial properties of the constituents of ajowan which prove to be useful in dentistry.

·         Aloe barbadensis (Aloe vera): Mangaiyarkarasi et al.,3 highlightened the utilization of Aloe vera in dentistry. Choonhakarn et al.,4 concluded through his randomized controlled trial studies that A. vera gel can be considered a safe alternative treatment for patients with oral lichen planus (OLP).   Donato et al.,5 identified the anti-inflammatory and wound healing activity of A. vera due to mannose-6 phosphate presence which can be used for the treatment of plaque-induced gingivitis.  Babaee et al.,6 conducted a double-blind clinical trial with 2% A. vera oral gel. The results of the studies presented that at this concentration the gel can prevent the recurrent aphthous stomatitis. Poor et al.,7 prepared SaliCept Patch obtained from the clear inner gel of A. vera. It is a freeze-dried pledget that contains Acemannan Hydrogel. This preparation proves to be effective in the treatment of alveolar osteitis. 

·          Propolis (Honey): Propolis based preparations have wide range of applications in the dentistry. Coutinho8, studied the honeybee propolis extract useful in periodontal treatment. A study carried out by Zare et al.,9 on Root canal disinfection using propolis proved that it is effective against Enterococcus faecalis and is an effective antimicrobial intra-canal agent. This is the best herbal alternate for the root canal infection. 5% Brazilian green propolis Pereira et al.,10 showed considerable decrease in gingival and plaque index in the alcohol free mouth wash preparation. Moreover, the preparation does not cause any side effect on hard and soft tissues of the mouth. Moraweic et al.,11 underwent the study to check effect of propolis containing toothpaste on patients suffering from periodontal problems allied with implants usage. The study presented the positive approach in overcoming gingivitis triggered by gingival plaque. Kouidhi et al.,12 highlightened the anti-cariogenic, anti-biofilms and anti-proliferative effects of different cell lines using the Tunisian propolis ethanol extract.


Table 1: Specifies the Pharmacognostic and Pharmaco-Chemical Characteristics of Allied Herbs.

Plant Name

Biological name


Chemical Constituents

Common Name


Trachyspermum ammi


·    Monoterpenes (p- cymene, γ-terpinene, β-pinene, β-phellandrene, myrcene, α- pinene, α-terpinene, α-thujene, β-selinene)

·    Phenol derivatives (thymol, terpinene-4-ol, carvacrol, terpinolene, trans-sabinenhydrate, linalool and α-terpineol)

bishop's weed

Aloe vera

Aloe barbadensis


·    Polysaccharides (pectins, hemicelluloses, glucomannan, acemannan, and mannose derivatives)

·    Amino acids

·    Lipids

·    Sterols (lupeol, campesterol, and β-sitosterol)

·    Tannins

Chinese Aloe, Indian Aloe, True Aloe, Barbados Aloe, Burn Aloe, First Aid Plant


 Apis millifera


·    Carbohydrates present are the monosaccharides fructose (38.2%) and glucose (31%); and disaccharides (~9%) sucrose, maltose, isomaltose, maltulose, turanose and kojibiose.




Fig 1: Three allied herbs used in dentistry




From the present work it can be concluded that Trachyspermum ammi, Aloe barbadensis and propolis can prove to be healthy herbal Aid in the dentistry. These agents along with other can be utilized in dentistry in an economical manner. Further, more clinical trials and pharmacological prospects can be studied for more rationalized approach.  



1.      Khan R, Zakir M, Khanam Z, Shakil S, Khan AU. Novel compound from Trachyspermum ammi (Ajowan caraway) seeds with antibiofilm and antiadherence activities against Streptococcus mutans: a potential chemotherapeutic agent against dental caries. J Appl Microbiol. 2010; 109(6): 2151-2159.

2.      Javed S, Ahmad AS, Muhammad SH, Aysha U, Rauf A, Sobia M. Nutritional, phytochemical potential and pharmacological evaluation of Nigella Sativa (Kalonji) and Trachyspermum Ammi (Ajwain). J Med Plat Res. 2012; 6(5): 768-775.

1.      3. Mangaiyarkarasi SP, Manigandan T, Elumalai M, Priyanka KC, Kaur RP. Benefits of Aloe vera in dentistry.  J Pharm Bioallied Sci. 2015; 7(Suppl 1): S255–S259.

3.      Choonhakarn C, Busaracome P, Sripanidkulchai B, Sarakarn P. The efficacy of Aloe vera gel in the treatment of oral lichen planus: A randomized controlled trial. Br J Dermatol. 2008; 158: 573–577.

4.      Donato JJ, Hartman GM, Haas RC. Anti-inflammatory and wound healing activity of a growth substance in Aloe vera. Davis RH, J Am Podiatr Med Assoc. 1994; 84(2):77-81.

5.      Babaee N, Zabihi E, Mohseni S, Moghadamnia AA. Evaluation of the therapeutic effects of Aloe vera gel on minor recurrent aphthous stomatitis. Dent Res J (Isfahan). 2012; 9(4): 381-385.

6.      Poor MR, Hall JE, Poor AS. Reduction in the incidence of alveolar osteitis in patients treated with the SaliCept patch, containing Acemannan hydrogel. J Oral Maxillofac Surg. 2002; 60(4): 374-379.

7.      Coutinho A. Honeybee propolis extract in periodontal treatment: A clinical and microbiological study of propolis in periodontal treatment. Indian J Dent Res. 2012; 23: 294.

8.      Zare JM, Toubayani H, Rezaei M. Propolis: A new alternative for root canal disinfection. Iran Endod J.  2012; 7:127-133.

9.      Pereira EM, da Silva JL, Silva FF, De Luca MP, Ferreira EF, Lorentz TC. Clinical evidence of the efficacy of a mouthwash containing propolis for the control of plaque and gingivitis: A phase II study. Evid Based Complement Alternat Med. 2011; 2011:750249.

10.   Moraweic T, Dziedzic A, Niedzielska I, Mertas A, Tanasiewicz M, Skaba D. The biological activity of propolis-containing toothpaste on oral health environment in patients who underwent implant-supported prosthodontics rehabilitation. Evid Based Complement Alternat Med. 2013; 15:704947.

11.   Kouidhi B, Zmantar T, Bakhrouf A. Anti-cariogenic and antibiofilms activity of Tunisian propolis extract and its potential protective effect against cancer cells proliferation. Anaerobe 2010; 16:566-571.





Received on 01.10.2019            Modified on 25.10.2019

Accepted on 15.11.2019            © A&V Publications All right reserved

Asian J. Res. Pharm. Sci. 2019; 9(4):288-290.

DOI: 10.5958/2231-5659.2019.00046.8