Volume No. :   9

Issue No. :  2

Year :  2019

ISSN Print :  2231-5640

ISSN Online :  2231-5659


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A Review on effectiveness of different Antiepileptic Drugs in Pediatric Febrile Seizures



Address:   Anusha Mendem*, Mamatha Arma, Vinodkumar Mugada, Raj Kiran Kolakota
Department of Pharmacy Practice, Vignan Institute of Pharmaceutical Technology, Duvvada, AP, India
*Corresponding Author
DOI No: 10.5958/2231-5659.2019.00013.4

ABSTRACT:
Febrile convulsions (FCs) are defined as seizures that occur in children between 6 months and 5 years of age, associated with fever but without intracranial infection or defined causes. The risk of developing epilepsy from a simple FC is 1.0–2.4%, and from a complex FC is 4.1–6.0%. The aim of the study was to assess the effectiveness of antiepileptic drugs in pediatric seizures. The data bases searched are pub med, trip database, science direct and Cochrane library The Type of study is observational studies and randomized control trails. In this study considerable Study population are Infant (1 month) to 6 yrs children. Intervention related to effective treatment of antiepileptic drugs in pediatrics. Patients with only febrile seizures and there treatment are included. Interventional studies are excluded. Children above 6 yrs age and adults are excluded. Patients other than febrile seizures are also excluded. In continuous anticonvulsant therapy, Phenobarbitone is most effective in prevalence of reoccurrence of febrile seizures, Valproic acid is least effective, Carbamazepine and phenytoin does not show any effective. In intermittent anticonvulsant therapy Diazepam is most effective. The effective dugs of antiepileptic drugs in pediatric seizures, Benzodiazepines given intravenously, liquid Diazepam is a safe, effective, and rational alternative. Phenobarbital is effective in recurrence of simple febrile seizures.
KEYWORDS:
Pediatrics, febrile seizures, antiepileptic drugs.
Cite:
Anusha Mendem, Mamatha Arma, Vinodkumar Mugada, Raj Kiran Kolakota. A Review on effectiveness of different Antiepileptic Drugs in Pediatric Febrile Seizures. Asian J. Res. Pharm. Sci. 2019; 9(2):85-90.
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