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Asian Journal of Research in Pharmaceutical Sciences
ISSN: 2231-5659(Online), 2231-5640(Print)
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Development and Validation of Stability Indicating RP-HPLC Method for Piracetam
Sushil D. Patil
Siddharth B. Bhalerao
Sushil D. Patil1*, Prajkta Varpe2, Sayali Chaure2, Siddharth B. Bhalerao2, Sanjay Kshirsagar2
1*Department of Pharmaceutical Chemistry, MET's Institute of Pharmacy, Bhujbal Knowledge City, Adgaon Nashik, Maharashtra, India.
2Savitribai Phule Pune University, Pune, Maharshtra state, India
A simple, rapid and validated HPLC method was developed for determination of Piracetam in film coated tablets. A Grace C18 (250mm x 4.6ID, Particle size: 5 micron) RP-18 column with a mobile phase consisting of Methanol: Water (20:80v/v) was used. Quantitative evaluation was performed at 205 nm. The HPLC method is selective, precise and accurate and can be used for routine analysis of preparations in pharmaceutical industry quality control laboratories.
RP-HPLC, Force Degradation study, Piracetam.
Sushil D. Patil, Prajkta Varpe, Sayali Chaure, Siddharth B. Bhalerao, Sanjay Kshirsagar. Development and Validation of Stability Indicating RP-HPLC Method for Piracetam. Asian J. Res. Pharm. Sci. 2017; 7(4):215-221.
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