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Asian Journal of Research in Pharmaceutical Sciences
ISSN: 2231-5659(Online), 2231-5640(Print)
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Preparation and In Vitro Charactersation of Fast Disintigrating Tablets of Cimetidine
Ramya Sri Sura
N.M. Vageesh1*, D Rafian1, U. Govindamma1, Ramya Sri Sura2
1St.Johns College of Pharmaceutical Sciences, Yerakota, Yemmiganur , Kurnool (Dist) , Andhra Pradesh
2Department of Pharmaceutics, OU Ph.D Scholar, Osmania University, Hyderabad
The present study was carried out to develop Fast Disintegration Tablets of Cimetidine. Kollidon, Vivasol, Tulsion 330 powder were used as Super Disintegrants. The blend of all the formulations showed good flow properties such as angle of repose, bulk density, tapped density. The prepared tablets were shown good post compression parameters and they passed all the quality control evaluation parameters as per I.P limits. Among all the formulations F7 formulation showed maximum % drug release i.e., 98.62% in 60 min hence it is considered as optimized formulation.
Cimetidine, Kollidon, Vivasol, Tulsion 330 and Fast Disintegration tablets.
N.M. Vageesh, D Rafian, U. Govindamma, Ramya Sri Sura. Preparation and In Vitro Charactersation of Fast Disintigrating Tablets of Cimetidine. Asian J. Res. Pharm. Sci. 2017; 7(3):141-148.
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