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Asian Journal of Research in Pharmaceutical Sciences
ISSN: 2231-5659(Online), 2231-5640(Print)
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Superdisintegrants: A Review
Rohan S. Gadakh
D.M. Shinkar1*, Rohan S. Gadakh1, R.B. Saudagar2
1Department of Pharmaceutics, R.G. Sapkal College of Pharmacy, Anjaneri, Nashik.
2Department of Pharmaceutical Chemistry, R.G. Sapkal College of Pharmacy, Anjaneri, Nashik.
Disintegrants are the substances that causes the rapid disintegration of the capsules or tablets into smaller particles that dissolves more rapidly than in the absence of the disintegrants. On the other hand superdisintegrants, are used to improve the efficacy of solid dosage forms. This is achieved by decreasing the disintegration time which in turn enhances drug dissolution rate. Superdisintegrants categories such as synthetic, semi-synthetic, natural and coprocessed blends etc. They are used in mouth dissolving tablet as well as conventional tablet to overcome the limitations of this dosage form. Superdisintegrants are generally used at a low conc. in the solid dosage form. The present review comprises the various kinds of Superdisintegrants like natural and synthetic which are being used in the formulation.
Superdisintegrants, Disintegrants, Fast release, swelling, wetting.
D.M. Shinkar, Rohan S. Gadakh, R.B. Saudagar. Superdisintegrants: A Review. Asian J. Res. Pharm. Sci. 2016; 6(2): 107-112.
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