Volume No. :   5

Issue No. :  1

Year :  2015

ISSN Print :  2231-5640

ISSN Online :  2231-5659


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Pleiotropic Effects of Statins



Address:   Puja S. Gaikwad1*, Dhanshri U.Gadhave1, Nayna V. Pimpodkar2, Trushali A. Mandhare1
1Lecturer, College of Pharmacy (D.Pharm) Degaon, Satara, (MH) India- 415 004.
2Principal, College of Pharmacy (D.Pharm) Degaon, Satara, (MH) India- 415 004.
*Corresponding Author
DOI No: 10.5958/2231-5659.2015.00009.0

ABSTRACT:
Statins are the most commonly prescribed drugs worldwide, are cholesterol lowering agents used to manage and prevent cardiovascular and coronary heart diseases. Recently a multifaceted actions in different physiological and pathological conditions has been also proposed for statins such as antiiflammation, neuroprotection etc. Statins have been shown to act through cholesterol dependant & independent mechanisms which are able to affect several tissue functions and modulate specific signal transduction pathways. Here we review the pharmacology of statins, providing a comprehensive update of the current knowledge of their effects on tissues, biological processes & pathological conditions; but statins are now becoming recognized as powerful anti-inflammatory agents that exert beneficial effects beyond low density lipoprotein cholesterol reduction.
KEYWORDS:
Pleiotropic Effects of Statins.
Cite:
Puja S. Gaikwad, Dhanshri U.Gadhave, Nayna V. Pimpodkar, Trushali A. Mandhare. Pleiotropic Effects of Statins. Asian J. Res. Pharm. Sci. 5(1): Jan.-March 2015; Page 55-58.
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