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Asian Journal of Research in Pharmaceutical Sciences
ISSN: 2231-5659(Online), 2231-5640(Print)
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Antihepatotoxicity of Hygrophila auriculata on CCl4 Induced Hepatotoxicity in Rats
T.S. Dhanaraj*, R. Gowthami, S. Rajlakshmi and K. Murugaiah
PG & Research Department of Biochemistry, Enathi Rajappaa College, Enathi, Pattukkottai, Thanjavur Dt., Tamil Nadu, India - 614 615
The objective of this study was to investigate the hepatoprotective activity of crude aqueous extract of leaves of Hygrophila auriculata against CCl4 induced hepatotoxicity. The leaves was dried in shade, they were powdered and Extracted with aqueous. The biochemical markers of hepatic damage like tested as MDA, GSH, Protein, Bilirubin, SGOT, ALP and SGPT recorded a significant alteration in CCl4 treated rats. However treatment with Hygrophila auriculata restored the level to near normal was observed. The potential hepatoprotective activity of Hygrophila auriculata is due to the presence of phytochemical constitution such as flavonoids and polyphenolic compounds present in plant.
Hepatoprotective, CCl 4 – Induced, Hygrophila auriculata.
T.S. Dhanaraj, R. Gowthami, S. Rajlakshmi, K. Murugaiah. Antihepatotoxicity of Hygrophila auriculata on CCl4 Induced Hepatotoxicity in Rats. Asian J. Res. Pharm. Sci. 2(4): Oct.-Dec. 2012; Page 140-142.
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