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Asian Journal of Research in Pharmaceutical Sciences
ISSN: 2231-5659(Online), 2231-5640(Print)
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Antistress activity of aqueous extract of leaves of Centella asiatica. Linn by in vivo methods.
P. Thamarai Selvi
M. Senthil Kumar
P. Thamarai Selvi*, M. Senthil Kumar, T. Kathiravan, R. Rajesh, J. Megala, S. Sravani
Department of Pharmacology, Annai Veilankanni’s Pharmacy College, Chennai-15, India.
The antistress activity of aqueous extract of Centella asiatica. Linn leaves (Umbelliferae) were studied at doses of 100mg and 200mg/kg against tail suspension test. A dose dependent reduction in immobility time was observed in TST. Imipramine (30mg/kg, i.p) was selected as reference standard. The extract also significantly potentiate the Phenobarbitone induced sleeping time in mice. The findings from the present investigation indicates the extract has significant antistress as shown by its effects on different experimentally induced animal models.
Centella asiatica, Antistress, Tail suspension test, Phenobarbitone induced sleeping time.
P. Thamarai Selvi, M. Senthil Kumar, T. Kathiravan, R. Rajesh, J. Megala, S. Sravani. Antistress activity of aqueous extract of leaves of Centella asiatica. Linn by in vivo methods. Asian J. Res. Pharm. Sci. 2(3): July-Sept. 2012; Page 91-94.
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