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Asian Journal of Research in Pharmaceutical Sciences
ISSN: 2231-5659(Online), 2231-5640(Print)
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Centrally Acting Analgesic Activity and CNS Depressant Activity of Cajanus cajan Linn
Sandeep B. Patil
Chandrakant S. Magdum
Vikas B. Awale
Sandeep B. Patil1*, Nilofar S.Naikwade1, Chandrakant S. Magdum2 and Vikas B. Awale3
1Department of Pharmacology, Appasaheb Birnale College of Pharmacy, South Shivaji Nagar, Sangli.
2 Department of Pharmaceutical chemistry Rajarambapu College of Pharmacy, Kasegaon, Sangli.
3 Department of Botany, Dr. Patangrao Kadam Mahavidyalya, Sangli, Maharashtra .
Cajanus cajan Linn which is synonymous to cajanus indicus is given different names like Red Gram. Pigeon Pea, Congo Pea and “Tur” by the local people of India. The plant is an erect shrub which grows height of 1.5 to 3 meters with many branches. The leaves are pinnately trifoliate and the leaflets are oblong-lanceolate and entire. The analgesic potency of aqueous extract of the leaves of Cajanus cajan Linn.and CNS depressant activity was investigated using animal model. Result showed that aq. extract of Cajanus cajan Linn. increased pain threshold in mice using hot plate methods and CNS depressant activity in mice by using actophotometer model. It is concluded that the Aqueous extract of Cajanus cajan Linn. can demonstrate strong analgesic and CNS depressant potency comparable in a times and dose dependant manner to a non steroidal anti-inflammatory drugs and benzodiazepines drug respectively.
Cajanus cajan Linn, analgesic activity, CNS Depressant activity
Sandeep B. Patil, Nilofar S.Naikwade, Chandrakant S. Magdum, Vikas B. Awale. Centrally Acting Analgesic Activity and CNS Depressant Activity of Cajanus cajan Linn. Asian J. Res. Pharm. Sci. 1(2): April-June 2011; Page 50-51.
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