Volume No. :   1

Issue No. :  2

Year :  2011

ISSN Print :  2231-5640

ISSN Online :  2231-5659


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Wound Healing Activity of Bauhinia purpurea in Albino Wistar Rats



Address:   K. Vijayabhaskar1, Macharla Sravanprasad2, Goli.venkateshwarlu1, P. Suvarna Devi3, K. Hemanth Kumar4 and J. Sunil5
1Venkateshwara Institute of Pharmaceutical Sciences, Nalgonda, Andhra Pradesh-508001.
2GBN Institute of Pharmacy, Ghatkeshar, RR District, Andhra Pradesh-501301.
3Saipranavi College of Pharmacy, Keesara, RR district Andhra Pradesh-501301.
4Shanta College of Pharmacy, Huzurabad, Karimnagar, Andhra Pradesh-505884
5Anurag College of Pharmacy, Kodada, Nalgonda, Andhra Pradesh-501301
*Corresponding Author
DOI No:

ABSTRACT:
The entire wound healing process is a complex series of events that begins at the moment of injury and can continue for months to years. The stages of wound healing are inflammatory phase, proliferation phase, fibroblastic phase and maturation phase. The objective of our study is to investigate wound healing activity of the methanolic leaf extract of of Bauhinia purpurea Linn in rats.. The leaf extract of Bauhinia purpurea (200 mg/kg/day) was evaluated for its wound healing activity in albino rats using excision and incision wound models. Bauhinia purpurea leaf extract treated animals exhibit 83.42 % reduction in wound area when compared to controls which was 76.22 %. The extract treated wounds are found to epithelize faster as compared to controls. Significant (p<0.001) increase in granuloma breaking strength (485±34.64) was observed. The povidone iodine ointment was used as standard.
KEYWORDS:
Bauhinia purpurea, Wound healing, Excision wound, Incision wound, Povidone iodine.
Cite:
K. Vijayabhaskar, Macharla Sravanprasad, Goli.venkateshwarlu, P. Suvarna Devi, K. Hemanth Kumar, J. Sunil. Wound Healing Activity of Bauhinia purpurea in Albino Wistar Rats. Asian J. Res. Pharm. Sci. 1(2): April-June 2011; Page 47-49.
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