Volume No. :   1

Issue No. :  1

Year :  2011

ISSN Print :  2231-5640

ISSN Online :  2231-5659


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Biomarkers: An Emerging Tool for Diagnosis of a Disease and Drug Development



Address:   Pradeep Sahu1*, Neha Pinkalwar1, Ravindra Dhar Dubey1, Shweta Paroha2, Shilpi Chatterjee1 and Tanushree Chatterjee1
1Institute of Pharmacy, RITEE, Chhatauna, Mandir Hasaud, Raipur, Chhattisgarh, India.
2Siddhi Vinayaka Institute of Technical Sciences, Mangla, Bilaspur, Chhattisgarh, India.
*Corresponding Author
DOI No:

ABSTRACT:
Biomarkers provide a dynamic and powerful approach to understanding the spectrum of disease with applications in observational and analytic epidemiology, randomized clinical trials, screening and diagnosis and prognosis. Defined as alterations in the constituents of tissues or body fluids, these markers offer the means for homogeneous classification of a disease and risk factors, and the can extend our base information about the underlying pathogenesis of disease. A prerequisite for the clinical use of biomarker is elucidation of the specific indication, standardization of analytical methods, characterization of analytical features, incremental yield of different markers for given clinical indications. Biomarkers can also reflect the entire spectrum of disease from the earliest manifestations to the terminal stages. The major use of biomarkers in clinical investigation.
KEYWORDS:
Diagnosis, Biomarker, Drug developments, Disease, Clinical Investigation.
Cite:
Pradeep Sahu, Neha Pinkalwar, Ravindra Dhar Dubey, Shweta Paroha, Shilpi Chatterjee, Tanushree Chatterjee. Biomarkers: An Emerging Tool for Diagnosis of a Disease and Drug Development. Asian J. Res. Pharm. Sci. 1(1): Jan.-Mar. 2011; Page 09-16.
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